A
Abdominal compartment syndrome 186
Aconite 363
Acrylonitrile, copolymer of 176
Acute cardiac arrest 342
Acute coronary syndrome 233
Acute kidney injury 2, 3, 7, 12, 19, 27, 36, 39, 40, 45, 47, 83, 93, 104, 114, 119, 121, 133, 135, 136, 166, 180, 182, 182b, 203, 368
determination 369
hospital-acquired 16
incidence of 12
male-female ratio of 13
management of 14
network 136
septic 111
treatment of 36
Acyclovir 137
Additives 71
Adult capillary leak syndrome 316
Advisory alarms 101
Airway 358
Akin classification 12
Alcohols 115
Aldosterone levels 112
Alkalemia, metabolic 79
Alkalosis, metabolic 79
Alpha-1-acid glycoprotein 131
American Society for Parenteral and Enteral Nutrition 389
Amikacin 138
Aminocaproic acid 269
Aminophylline 157
Amnesia 304
Ampicillin 137
Anaphylaxis, acute 233
Anesthetists, cardiac 3
Aneurysm 339
Anion gap 97
Anthropometry 120
Antiarrhythmic agents 363
concentration-dependent 137
hydrophilic 126
lipophilic 126
prophylaxis 394
therapy
optimum 125
standard principles of 397
Anticonvulsants 157
Antiendotoxin neutralization therapy 170
Antiepileptics 363
Antifibrinolytics 269
Antifungals 132
Anti-inflammatory mediators 172
Antimalarial agents 363
Antimicrobial dosing, assessment of 125
Antineutrophil cytoplasmic antibodies 166
Antiplatelet drugs 269
Antistreptolysin-O antibody 182
Antithrombotic activity 276
Antivirals 132
Anuria 19
Anxiolysis 304
Aortic dissection 355
Arachidonic acid 265
Arterial pressure monitor 60
Arteriovenous system 334
Atrial natriuretic peptide hormone 369
Atrial pressure, left 409
Azithromycin 130
Azole antimycotics 132
Azotemia, prerenal 14
Aztreonam 137
B
Backflow cannula 346
Basal metabolic rate 213
Bilirubin 172
Bioelectrical impedance analysis 97
Bioimpedance vector analysis 97
Bispectral index 304
Biventricular assist device 404
Bladder perforation 185
Blalock-Taussig shunt, modified 416
ammonia level 89
conservation strategy 312
citrate complexes 79
gastrointestinal 386
low 334
measurement 283
turbulent 73
leak alarm 149
causes 149
troubleshooting 149
leak detector 59
loss 79
priming 259
products 329
pump 142
rheological properties 166
rheology 147
stasis of 73
stream infections 393
restricted use of 231
trauma 258
vessels 346
accidental puncture of 152
volume 242
intravascular 68
Bone marrow transplantation 180
Breathing 358
Brittle circulation 83
Bupropion 363
C
Calorie protein requirements 385
Canadian Critical Care Trial Group 311
Candida albicans 394
Carbamates 363
Carbamazepine 363
Carbapenems 134
Carbohydrate requirement 122
Cardiac disease 16
Cardiac resynchronization therapy 327
Cardiac support, connections for 371
Cardiac trauma, isolated 233
Cardiopulmonary function 87
Cardiothoracic surgeon 228
Cardiotoxic drugs 362
Cardiotoxic toxins 363
Cardiovascular toxicity 362
Catabolism, prevention of 183
Catheter
blockage 153
dislodgement 339
insertion 338
site
bleeding 338
infection 338
troubleshooting 100
Cefepime 138
Ceftazidime 138
Cellular cascade 169
Cellulose 25
Celphos 1
Centers for Disease Control and Prevention criteria 396
Central nervous system 158
Cerebral
cardiopulmonary resuscitation 343
edema 87
hypoxemia 208
hypoxia 202
near-infrared spectroscopy 289
perfusion pressure 113
Chelating agent 77
Chloramphenicol 126
Chloroquine 363
Chromosomal disorder 408
Chronic circulatory support system 359
Cilley test 328
Circuit 240
components 371
filter life 11
integrity 93
monitoring of 96
management 394
pressures 100
priming 260
suspected infection of 321
tubing rupture 355
accumulation 79
management of 79
anticoagulation 95
protocol 64t
based solutions 61
infusion, rate of 78
regional anticoagulation 69
titration of 78
use
contraindication of 380
indication of 380
Clot formation 339
Coagulase-negative staphylococci 394
Cocaine 363
Colchicine 363
Colloidal dispersion 132
Commercial hemoperfusion adsorbents 159t
Communication unit 57
Complex phenomenon 137
Computed tomography 288
Confusion assessment method 305
Continuous peripheral capillary oxygen saturation 285
Continuous renal replacement therapy 2, 7, 14, 20, 29, 34, 36, 37, 42, 43, 47, 49, 56, 58t, 61t, 64t, 66, 67t, 69, 71t, 72, 73, 74t, 83, 84, 84t, 88, 89, 90, 92, 93, 95, 97, 97t, 102, 104-106, 111-116, 119, 125-127, 127t, 136, 140, 151, 170, 172, 184, 188, 368, 371, 372, 372f, 373, 373f, 375, 375, 375f, 376, 377f-379f, 381
basic components of 57f
circuit 371
duration of 381
indications for 369
modes of 84
position of 382
prescription 188
process 57f
separate 374
termination of 104
types of 58t
Convective therapy 127
Conventional extracorporeal therapies 161
Cooler machine 242
Copper 123
Countercurrent flows 31f
Creatine phosphokinase 182
Critical care unit 29
Cyanide 363
Cytosorb technology 176
D
Dacron T-graft 200
Danaparoid 76
Danger-associated molecular pattern 171
D-dimer 273
Deaeration chamber 59
Deep vein thrombosis 252
Depression, cardiac 233
Desipramine 363
Desmopressin 269
Determine fluid balance 96
Device failure 339
Dexmedetomidine 303
Diabetes mellitus 155
Diabetic nephropathy 155
Dialysis
catheters 64t
continuous 371
dose/adequacy 51
duration of 187
filter fiber's clotting 147
fluid 374
method of clearance during 84t
modalities 42t
solution, temperature of 62
technicians 3
Diastolic dysfunction 325
Diazepam 25
Diethylenetriamine pentaacetic acid 182
Different arterial cannulation techniques 202t
Digitalis compounds 157
Disposable pressure transducers 283
Disseminated intravascular coagulation 15
Distal perfusion catheter 317
Dopamine 363
Downstream resistance 242
Doxycycline 130
Drug 363
charge 127
general principles 128
limitations 129
loading dose 128
maintenance dose 128
factors 126
lipophilic 157
molecule, size of 26
overdose/toxicity 233
protein 126
removal 127t
sequestration of 302
site-specific nephrotoxicity of 16f
toxicity 88
toxins 365
Dual-lumen jugular catheters 2
Dynamic outflow tract obstruction 325
Dysnatremia 40
E
Ebola virus disease, severe 177
Echinocandins 132
Effluent bag 146
Ejection fraction 324
Electrical impedance tomography 297
Embolism, pulmonary 233
Endogenous toxins, removal of 115
Enzymes 165
Ertapenem 53
Estimated glomerular filtration rate 136
European Medicine Agency 136
European Resuscitation Council Guidelines 350
Excessive pump suction 206
Exogenous toxins, removal of 115
Extracorporeal immunomodulation 67
Extracorporeal membrane oxygenation 7, 67, 83, 195, 197, 202t, 209, 212, 218f, 223f, 226, 227, 229, 231, 233-235, 238, 240, 242, 251, 264, 265f, 270, 275, 276, 282, 286t, 287, 291, 294, 295, 297, 301, 302, 302fc, 305, 306, 308, 311-313, 316, 321, 324, 327fc, 330fc, 333, 345, 353-355, 358-361, 363, 368-372, 372f-374f, 377f-379f, 381, 382, 385, 393, 396, 397, 403, 406-409, 412, 414t, 415, 415t, 417, 417t, 418
arteriovenous 355
cannula size 375
cannulation 409
carbon dioxide removal 333
cardiac issues in 353
catheter insertion 247f
component 217
independent of 374
physiology 218
pressure monitoring 283
priming of 259
operator 346
contraindications of 355t
controversies of 381
coordinator 228
devices, portable 345
director 228
disposables 248f
flow 414
induced hypertension 321
initiation safety checklist 262
machine 238
management 224
neurological
complications of 319
monitoring during 288
oxygenation 223
physiology of 282
pumps, hydrodynamic characteristics of 242t
sedation algorithm 305fc
sepsis 3
setup, typical 337
specialist 228
stages of 287t
system 239f
team 226
components of 226
formation of 227f
mobile 229
therapy 306
titration of sedation in 304
transfusion therapy during 308
treatment of infections on 397
ventilation strategies on 416
ventilator settings during 293fc
weaning 324
Extracorporeal treatment 151
F
Femoral vein, left 208
Fibrosis, retroperitoneal 16
Fick's law 20
adsorption 24
and circuit parameters 100
biocompatibility 24
clotting 148
flux 24
pressure 142
drop 142
extremely positive 146
surface area 25
thickness 24
First-generation devices 404
Fistula, severe bronchopleural 232
Fluconazole 138
Fluid
administration, predilution 94
balance 96
achieving 85
alarm 149
errors 99
negative 22
containing alkali 94
control unit 60
effluent 374
homeostasis 83
precision 94
prescription, stepwise 95
principles of 95
transfusion, restricted use of 231
urea nitrogen 96
volume of 185
Folate 123
Fontan procedure 417
Food and Drug Administration 136
G
Gamma-aminobutyric acid 304
Gastrointestinal complication 355
Gestational age 344
Glenn procedure, bidirectional 417
Glycopeptides 126
Glycosaminoglycan 177
Glycosides, cardiac 363
Graft dysfunction, primary 400
Gram-positive bacteria 186
Guillain-Barré syndrome 165
H
Harris-Benedict's equation 389
Heart 346
disease
congenital 199
ischemic 155
failure 87
acute decompensated 87
congestive 112
decompensated 112
right 199
rate 51
Heater machine 242
Heavy sedation 386
Hemoconcentration 73
continuous
arteriovenous 42
venoarterial 371
conventional intermittent 47
pediatric 187t
vascular catheters for 186t
urgent-start 151
Hemorrhage 258
intracranial 403
intraventricular 408
major 403
pulmonary 356
uncontrolled 344
vessel perforation with 207
Hemothorax 258
Henoch-Schönlein purpura 15
Heparan sulfate 177
anticoagulation action of 318
bolus 51
coated circuit 268
free method 63
infusion 329
method 63
protocol 63t
resistance 266
systemic 68
therapy 63
Heparinase thromboelastogram 266
Heterogeneous syndrome 17
High parasitic index 166
High positive end-expiratory pressure 291
Hospital cardiac arrest 347
Human albumin 172
Human cells 177
Hydrophobic membrane 371
Hypercalcemia, management of 79
Hypercapnia 331
Hypercatabolic state 152
Hypercytokinemia 171
Hyperfibrinolysis 318
Hypermagnesemia 40
Hypernatremia, management of 79
Hyperparasitemia 166
Hyperplasia, benign prostatic 15
Hypersensitivity 133
Hypertensive emergency 183
Hypertrophy, left ventricular 402
Hypervolemia, worsen 88
Hypoalbuminemia 16
Hypoperfusion 418
Hypophosphatemia 160
Hypoplastic left heart syndrome, Norwood stage I procedure for 418f
Hypotension 362
I
Imipramine 363
Immunohomeostasis 170
Immunological dysfunction 168
Inadequate systemic perfusion 418
Inadvertent arterial insertion 339
Induction trainings 9
Indwelling catheter 99
Infectious diseases 16
Inflammatory mediators 177
Inflow pressure 141
Influence adsorptive capacity 160
Infusion pump 374
Inspired oxygen fraction 364
Intensive care delirium screening checklist 306
Intensive care unit 1, 7, 13, 19, 36, 39, 47, 67, 140, 151, 152, 181, 228, 282, 303, 305, 306, 308, 385, 393
complications 153
nurse 228
Intermittent heparin bolus method 63
International Extracorporeal Life Support Organization 406
Intoxication, acute 362
Intracranial pressure, high 106
Intrinsic coagulation system 73
Ionized calcium levels 259
Ischuria renalis 12
Isotonic solution 182
Itraconazole 132
L
Large volume resuscitation, impact of 387
Lectin protein 177
implantation 199
distension 356
end-diastolic
pressure 409
volume 409
failure 325
rupture 356
thrombus formation 356
Leukocytapheresis 164
Leukocytes 163
Leukocytosis 321
Leukopenia 160
Lipemia 272
Lipopolysaccharides, removal of 171
Lipoprotein, low density 166
Liposomal dispersion 132
Lorazepam 304
Loss pulsatile flow 319
Low cardiac output, presence of 418
Lower tidal volume ventilation 339
Lymph circulation 171
M
Macrolides 126
Magnesium 62
Magnetic resonance imaging 288
Malaria 166
Meprobamate 363
Metabolic derangements 369
Metabolic monitoring 288
Metformin 37
Methicillin-resistant staphylococcus aureus, treatment of 133
Metronidazole 130
Microangiopathy, thrombotic 166
Microcirculatory flow 166
Mid-arm circumference 120
Midazolam 304
Monitor anticoagulation, tests to 271t
Monmouth junction 176
Mortality 53
Multifiltrate machine, pediatric filters for 188t
Multiorgan dysfunction syndrome 39
Multiorgan support therapy 168
Multiport venous cannula 252f
Myocardial dysfunction, severe 409
N
National Institutes of Health 291
National Kidney Foundation Kidney Disease Outcomes Quality Initiative 120
Neonatal respiratory extracorporeal membrane oxygenation 408
Nephropathy, HIV-associated 16
Nephrotoxic drugs, omission of 183
Nephrotoxicity, drug induced 15
Neurological disorders 86
Neurological injury, acute 113
Neuropathy, peripheral 133
Neutrophil gelatinase-associated lipocalin 106
New monitoring systems 297
N-methyl-D-aspartate 303
Nonsteroidal anti-inflammatory drugs 15
Norepinephrine uptake inhibitors 363
North South syndrome 256
Novalung interventional lung assist 337f
Nutritional requirements, estimation of 121
Nutritional support, adequate 88
O
Observational studies 295
Obstetrical diseases 16
Oozing 152
Oral nutritional supplementation 121
Organophosphates 363
Orthotopic liver transplantation 114
Outflow cannula 245
Overanticoagulation 318
OXiris hemofilter 176
P
Pancreatitis 231
Paraplegia 319
Pediatric intensive care unit 181
Perfusionists handling dialysis 3
Pericardial tamponade 325
Peristaltic pumps 242
advantages of 155
automated 153
catheters, types of 184f
continuous cyclic 134
current status of 151
disadvantages of 155
emergent-start 152
fluid 153
nocturnal intermittent 134
prescription
complications 185
modifications 185
monitoring 185
types of 134t
urgent-start 151
use of 45
Peritoneal pleural connections 45
Peritonitis 186
Pesticides 363
Pharmacokinetic parameters 125
Plant toxins 363
adjusting 86
concentrations 113
electrolyte 94
anticoagulant for 165
protein binding 126
capacity 126
refilling rate 68
remove from 23
renin activity 321
Pneumothorax 258
Poly-4-methyl pentene 335
Polycarbonate 60
Polycyclic antidepressants 363
Polycystic kidney disease, autosomal dominant 155
Polymethylpentene 242
Poor single ventricle function 418
Positive access pressure implies arterial cannulation 144
Positive pressure ventilation, low frequency 335
Postcardiac surgery, support 199
Postcardiotomy 409
Post-heart 199
Post-weaning 326
Prealbumin 120
Preblood pump 72
Priming, types of 259
PrismaFlex machines, pediatric filters for 188t
Pro-inflammatory forces 171
Propofol 304
Propranolol 25
Prostaglandin 76
Prothrombin time 270
Prune Belly syndrome 186
Pulsed high-volume hemofiltration 29
Pyridoxine 123
Q
QT interval prolongation 133
Quality improvement programs, development of 10
Quality-adjusted life year 348
Quinine 363
R
Randomized clinical trials 166
Rated flow, concept of 216f
Regional citrate 68
advantages 78
complications 79
method 63
principle and mechanism of action 77
technique 78
Regional heparin protamine anticoagulation 77
Regurgitation, mitral 325
Renal dysfunction 362
classification, pediatric risk of 180
criteria, pediatric risk of 181t
risk of 180
Renal elimination, degree of 127
Renal intensive care unit 153
Renal replacement therapy 1, 5, 7, 11, 13, 19, 23t, 25, 29, 33, 36, 39, 40, 44, 49t, 90t, 113, 119, 120t, 121, 125, 127, 151, 172, 180, 181, 183, 184, 364, 368, 381
aims of 40
circuit 141f
complications of 45
hardware regulation 9
hybrid 29
nonrenal indications for 37t
prescription of 26
programs 11
troubleshooting in 140
Renal vasoconstriction 15
Respiratory 98
acidosis 336
depression 362
embarrassment 186
extracorporeal membrane oxygenation
for neonates 408
indications for 409t
function, monitoring 287
monitoring 287
rate 296
therapist 228
Resuscitation
continuous cardiopulmonary 361
Retrograde reperfusion 239
Rhabdomyolysis 16
Rigid peritoneal dialysis catheter 185f
Ringer's lactate 182
Rodenticides 363
Roller pump 412
S
Second-generation devices 404
Seizures 362
Selenium 123
intra-abdominal 112
mediators, pleiotropia of 169
pathobiology of 168
pathogenesis of 168
with profound cardiac depression 233
Septostomy, atrial 356
Shunt 207
Sickle cell disease 166
Sieving coefficient 127
Skin fold thickness 120
Society of Critical Care Medicine 389
Solid organ transplant 167
Sorbent application, modes of 161t
Spinal cord infarct 319
Spontaneous awakening trials 305
Spontaneous breathing trials 305
Standard operating procedures 8
Steroids, use of 386
Stuivenberg hospital acute renal failure 53
Substitution fluid, part of 78
Swan-Ganz catheter 285
Sweep flow 215
Systemic infections, prevention of 395
T
Taxus 363
Tenckhoff type 184f
Tendon rupture 133
Tetracycline 126
Thebesian veins 254
Theranostic circuit devices 175
Therapy, timing of 174
Thiamine 123
Third-generation devices 404
Threshold modulation theory 171
Thrombocytapheresis 164
Thromboelastography 277
Thromboembolism 357
Tigecycline 130
Tissue
binding 158
factor pathway inhibitor 318
hypoperfusion 15
absence of 15
signs of 234
plasminogen activator 318
Toxic accumulation 183
Tranexamic acid 269
Tranquillizers 157
Transcatheter aortic valve implantation 236
Transcranial Doppler 288
Traumatic brain injury 106
Triglycerides 389
Triple cannulation 257
Trisodium citrate 78
Tubular drug handling 137
U
Ulinastatin 171
Ultra high-volume hemofiltration 29
Ultrasonic flow probes 283
Ultrasonography 414
Uremia, symptomatic 19
V
Valproic acid 37
Vascular cannulas 245
Vascular injury 317
Vascular structure, laceration of 258
Vasodilatation, systemic 15
Vasopressor support 386
Venoarterial extracorporeal membrane oxygenation 197, 198f, 201t, 202, 209, 218, 220, 221f, 232, 239, 251, 254, 255f, 257, 257f, 258f, 286, 287, 327, 342, 353, 354, 354f, 355, 358, 416
complications of 203b
physiology of 283
weaning 324
Venovenous extracorporeal membrane oxygenation 203, 204f, 205, 205t, 207, 207b, 208, 209, 220, 221, 222f, 227, 231, 239f, 251, 252, 253f, 257, 257f, 258f, 287, 292, 294, 327, 330, 354, 355, 361, 385
physiology of 282
system functions 231
Ventricular ejection fraction 366
Volume exchange transfusions 271