Early Clinical Exposure: A Case Based Approach in Clinical Physiology Manjinder Kaur, Naren Kurmi, Sangita Chauhan
INDEX
Page numbers followed by f refer to figure and t refer to table.
A
Abdominal examination 14
Aberrant conducting tissue 40f
Acetone breath 80
Achalasia cardia, pathophysiology of 32f
Acid neutralizing drugs 28
Acid peptic disease 26
etiology of 27f
Acidosis 76
Acne 71
Acromegaly 71
clinical features of 72f
Activated partial thromboplastin time 13
Acute mountain sickness 56
pathophysiology of 56f
Air conduction 105, 106
Aluminium salts 28
Alzheimer's brain 103f
Alzheimer's disease 102
Amenorrhea 88
primary 114
Anemia 5
classification of 2
clinical classification of 3t
etiological classification of 2t
grades of 3
hemolytic 8
morphological classification of 2, 2t
Anorexia 80
Antacids 28
Anticholinesterase drugs 17
Antihypertensive medication 75
Antisecretory drugs 28
mechanism of action of 28f
Apathy 1
Aphasia 100
types of 101t
Apoferritin 3
Appetite, loss of 1, 82
Atrioventricular
conduction block 38
nodal blocks 38
node 38
Autoimmune 76
thyroiditis 64
Azoospermia 115
B
Barium swallow 32f
Basal ganglia 95f
Beta-amyloid plaques cause 103
Bicarbonate therapy 81
Bird beak appearance 32f
Bleeding time 13
Blood
loss 2, 73
pressure 61
urea nitrogen 61
Blurred vision 24
Body
ache 54
fluids, loss of 45
Bone conduction 105, 106
Botulism, pathophysiology of 24f
Breast enlargement 90
Breath 54
severe shortness of 41
shortness of 41
Breathlessness 1, 41, 50
Brown tumor, physiological basis of 83f
Brown-Sequard syndrome 92
clinical features of 93f
Brushfield spots 112
C
Caisson's disease 54
pathophysiology of 54f
Carbohydrate metabolism 77
Cardiac failure 41
Cardiac muscle 38f
Cardiovascular system 23
Carpopedal spasm, physiological basis of 85f
Caudate nuclei 95
Central nervous system 23, 102
examination 58
Cerebellar ataxia 96
Cerebellar function test 100
Cerebellum, functional division of 97f
Cerebrocerebellum 96
Chest
heaviness 47
muscles 24
Cholesterol, serum 73
Chromosomal aberrations, physiology of 112
Chronic obstructive pulmonary disease 50, 52, 53
clinical features of 53f
pathophysiology of 52, 52f
Chronic renal failure 61, 61t, 62
pathophysiology of 62f
Clostridium botulinum 24
Cochlear implants 106
Cold
intolerance 63
weather 99, 99t
Color vision 107, 109
Concave lens, use of 107f
Concussion, severe 96
Conductive deafness 105
Confrontation test 107, 109, 110
Congestive cardiac failure
management of 44, 44f
pathophysiology of 42, 43f
Consciousness, loss of 100
Constipation 35, 63, 82
Convulsions 54
Cornea 108
Cortical sensations 94
Cortisol 73
Cranial nerve examination 100
Creatinine, serum 61
Crude touch, sensation of 92
Cry, excessive 10
Cushing's syndrome 73
clinical features of 74f
D
Deaf ear 105t
Death 23
Deep vein thrombosis 89
Dehydration, signs of 80
Dehydroepiandrosterone 73
Diabetes mellitus 75
juvenile 79
pathophysiology of 78f
primary 76
secondary 76
Diabetic ketoacidosis 79
clinical features of 80f
pathophysiology of 80
Diarrhea 5
Digestive tract 26
Diplopia 16
Distant vision 110
Divalent metal transporter 3
Dizziness 37, 56, 98
Double vision 16
Down's syndrome 112
pathophysiology of 113f
Dry skin 63
Duchenne muscular dystrophy 21
clinical features of 21f
pathophysiology of 21f
Duodenal ulcer 27, 27t
Dysarthria 101
Dyspnea, mild 47
E
Ear 105, 105t, 106
Echocardiography 42f
Edema, lower extremity 61
Electrodiagnostic repetitive nerve stimulation 17
Elevated fasting blood sugar, basis of 71
Embolism, pulmonary 89
Emesis 61
Endocrinal functions 90
Endocrine physiology 63
Enteric nervous system 35f
Enterochromaffin 28
Epigastrium 26
Erectile dysfunction 86
Erythroblastosis 11
fetalis 10
Erythroblasts 11
Extracorpuscular defects 8
Extreme tiredness 24
Eye 107f
F
Facial expressions 94
Facial hair 73
Far vision 107, 109
Fasting blood
glucose 75
sugar 73
Fat metabolism 77
Fatigability 16
Fatigue 56, 63
Ferro protein transporter 3
Fever 100
Fluent aphasia 101
Fluid replacement 81
Follicle stimulating hormone 89
Foodborne botulism 24
sources of 24
Fracture 96
G
G-6-PD deficiency 8
pathophysiology of 8, 9f
Gait, shuffling 94
Gastric 7
ulcer 27, 27t
Gastroesophageal reflux disease 30
pathophysiology of 31f
Gastrointestinal system 23, 26
Gastrointestinal tract 3, 3f, 5, 6f
organization of 35f
Giddiness 22
Global aphasia 101
Globus pallidus 95
Glomerular filtration rate 89
Glucosuria 76, 89
H
Hair cells, loss of 106
Hashimoto's thyroiditis 64
HCL, mechanism of secretion of 28f
Headache 56, 71, 107
Healthy neuromuscular junction 18f
Hearing
aids 106
loss 104, 106
conductive 104
test 105
Heart 38f
block 37
classification of 39f
first degree 38
second degree 38
third degree 38
types of 38
rate 1, 89
Heat
balance, methods of 98f
gain 99
loss 99
stroke 98
Helicobacter pylori infection 27
Hematology 1
Hemoglobin 1
beta-globin chain of 14
concentration of 3
electrophoresis 14
Hemolytic anemia 8
causes of 8t
Hemolytic disease, pathophysiology of 10, 11f
Hemophilia 12
A 13f
pathophysiology of 12f
Hemorrhage 45
intracranial 103
Hepatobiliary system 90
High performance liquid chromatography 14
Hirschsprung's disease 35
pathophysiology of 36f
Hirsutism 71
Hormone assay 87
Hot weather 99, 99t
Human chorionic somatomammotropin 90
Hydrops fetalis 10
Hyperglycemia 76, 77
Hyperkalemia 76
Hyperkinetic features, causes of 95
Hyperparathyroidism 83f
primary 82, 83
secondary 83
Hypertension 61
Hyperthyroidism 67
clinical features of 68f, 69f
pathophysiology of 67f
Hypertonia 94
Hypocalcemia 85f
Hypoparathyroidism, secondary 84
Hypothyroidism 63
Hypovolemic shock 45
causes of 45, 45t
management of 46f
pathophysiology of 46f
I
Icterus 14
gravis neonatorum 10
Immunity, passive 10
Immunological test 88f
Impulse, transmission of 18f, 38f
Indigestion 5
Infertility
male 86
primary 86
Insulin
deficiency of 77t
infusion of 80
lack of 79
physiological actions of 77f
Interstitial fluid 28
Intracorpuscular defects 8
Iodine deficiency 64
Iron
absorption of 3, 3f
deficiency anemia 1, 2
clinical features of 4f
pathophysiology of 4
Ishihara's color plates 107, 109
J
Jaeger's chart 107, 109
Jargon speech 101
Jaundice 10
obstructive 33
Joint pains 14
K
Kent bundle 40f
Ketosis 76
Kidneys 45
Klinefelter's syndrome 115
pathophysiology of 115f
Knee, hematoma of 12
Koilonychia 1
Kussmaul breathing 80
L
Lambert-Eaton syndrome, pathophysiology of 20f
Legs 24
Lens, curvature of 108
Lesions, effects of 111f
Lethargy 61
Libido, loss of 86
Lightheadedness 37
Limbs 100
Lipid profile 75
Lipoprotein lipase 77
Lithium 64
Logorrhea 101
Lower esophageal sphincter 89
Lower motor neuron 92
Lung disease, restrictive 53
Luteinizing hormone 89
M
Magnesium 28
Malaise 98
Mean corpuscular
hemoglobin concentration 1
volume 1
Menstrual cycles 67, 71
Mental retardation, mild degree of 112
Metabolism 77f
Micturition 58, 75
frequency of 75
Mini-mental state examination test 102
Mood swings 67
Motor
aphasia 101
examination 100
functions 94
loss 92
vehicle accident 96
Mountain sickness, acute 56
Murmur, systolic 1
Musculoskeletal physiology 16
Myasthenia gravis 16, 20f
pathophysiology of 19f
Myocardial infarction 47
Myopia 107
Myopic eye 107f
N
Nausea 47, 56, 61, 98
Near vision 107, 109
Neologism 101
Neostigmine 17
Nerve deafness 105
Nervousness 67
Neurogenic bladder 58
dysfunction, pathophysiology of 59f
Neuropathy, peripheral 5
Non-fluent aphasia 101
Nonsteroidal anti-inflammatory drugs 27
O
Obstructive jaundice 33
features of 34f
pathophysiology of 34
Obstructive lung disease 53
Oily skin 71
Orthodontics 112
P
Packed cell volume 1
Pain 8f, 26, 104
abdominal 80
retrosternal 30
Pallor 1, 14
Palpitations 40
Paraphasia 101
Parkinson disease 94
pathophysiology of 95
Peripheral blood film 1, 14
Phalanges, subperiosteal bone resorption of 82f
Phospholipid 12
Plasma
glucose level 77
volume, loss of 45
Poikilocytosis 8
Polychromasia 8
Polydipsia, physiological basis of 78f
Polyphagia, physiological basis of 78f
Polyuria 80
physiological basis of 78f
Post-thyroidectomy
hypoparathyroidism 84
hypothyroidism 85f
Potassium replacement 81
Pregnancy 88, 89f
normal 88
Presbycusis 106
Presbyopia 109
pathophysiology of 109f
Primary hyperparathyroidism 82, 83
clinical features of 83f
Primary hyperthyroidism 70
Prophylaxis 10
Proprioception 92
Prostaglandin analogs 29
Protein metabolism 77
Prothrombin time 13
Proton pump inhibitors 29
Proximal muscle weakness 16
Pruritus 61
Ptosis 16
Puffer fish 22f
Punctum proximum 109
Putamen 95
R
Rapid breathing 80
Reflexes, pupillary 107, 109
Refractive error, correction of 107f
Renal blood flow 89
Renal failure 61
acute 61, 61t, 62
chronic 61, 61t, 62
Renal function tests 75
Renal transplant, indications of 58
Repetitive speech, sudden onset of 100, 100f
Reproductive physiology 86
Respiratory physiology 50
Respiratory system 23, 89
examination of 50
Restlessness 100
Retina 107f
Rinne's test 105, 106
Road traffic accident 58
Romberg sign 97
S
Salt and pepper sign 82f
Schwabach test 105, 106
Semen analysis 87
normal 87t
Sensory
aphasia 101
ataxia 97
function 94
loss 92
Shock
hypovolemic 45
management of 46
stages of 45, 45t
Short stature 114
webbed neck 114
Sickle cell anemia 14
pathophysiology of 15f
Sickling test 14
Slight memory loss 63
Snare proteins, types of 25
Snellen's chart 107, 109
Snore 71
Sore throat 104
Special senses, physiology of 104
Speech 100, 101f
agrammatic 101
slow 63
Sperm
count 87
morphology 87
Spinal cord 58f
Spinocerebellum 96
Spirometer, parameter of 53
Spirometry 51, 51f
Stiffness 92
Stimulates hormone sensitive lipase 77
Stokes-Adams syndrome 38
Stress management 28
Striatum 95
Substantia nigra 95
Subthalamic nucleus 95
Supraventricular tachycardia 40
Sweating 99
excessive 71
Swollen knee 12
Synaptobrevin 25
Syncope 37, 40
Syntaxin 25
T
Tachycardia 50
Tachypnea 50
Tactile discrimination 92
Tanner stage 114
Tau proteins 103
Testosterone 73
levels 71
Tetrodotoxin poisoning 22
pathophysiology of 23f
Thyroid
Gland
abnormal 64
removal of 84
hormone secretion, regulation of 66f
nodule 84
synthesis, inborn errors of 64
Thyroidectomy 84
Total iron binding capacity 1
Touch sensation, loss of 92
Trans ferritin 3
Tremors 94
Tuning fork test 105t, 106t
Turner's syndrome 114
pathophysiology of 114f
U
Ulcer 29
Upper motor neuron 92
Urinary bladder 58
Urinary tract infection 89
V
Vasoactive crisis 15
Vestibulocerebellum 96
Vibration 92
Vision, field of 107, 109
Visual acuity 107, 109, 110
Visual disturbance 71
Visual pathway 110, 111f
Vitamin B12
absorption of 5, 6f
deficiency 5
causes of 7t
Vomiting 45, 98
W
Water loss 34
Weakness 16
signs of 100
Webbed neck 114
Weber test 105, 106
Weight
gain 63, 90
loss 30
Wolff-Parkinson-White syndrome 40, 40f
X
X chromosome 114, 115
X-ray
chest 51f
hand 82f
skull 82f
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