Handbook of Fungal Infections Kiran V Godse, Anant Patil
INDEX
Page numbers followed by, f refer to figure, and t refer to table.
A
Allylamines 52, 53, 59, 69, 72
Alopecia 62
Amorolfine 69
Amphotericin B 54, 70
colloidal dispersion 55
deoxycholate 52
lipid complex 52, 55
Anemia 55
Anidulafungin 52
Antibiotics, utilization of 34
Antifungal
agents 52, 63
classification of 52t, 53, 53t
pharmacology of 52
resistance 62
topical 81
Antimetabolites 53, 61
Archaea 33
Athlete's foot 14
Azoles 52, 53, 56, 59
mechanism of action of 56f
B
Bacteria 33
Balanitis 34, 37, 37f, 38, 39
types of 38
Balanoposthitis 37
Benzylamines 69
Bifonazole 69
Bone marrow suppression 62
Burning 34
Butenafine 69
Butoconazole 36
C
Candida 34
albicans 33, 55, 63
infections 16
krusei 63
neoformans 63
Candidal balanitis 38
Candidal intertrigo, systemic agents for 84
Candidemia 58
Candidiasis, topical agents for 73
Cardiac dysfunction 82
Caspofungin 52, 64
Castellani's paint 70
Cell membrane 53
Cell wall 53
Central nervous system 58
Cerebrospinal fluid 57
Chemical structure 52
Ciclopirox 53, 70
olamine 71, 72
Circinate balanitis 38
Clioquinol 53
Clotrimazole 36, 52, 69, 72
Corticosteroids 62
modified double-edged tinea 10f
topical 42, 43, 47
Cryptococcus neoformans 63
D
Dermatophyte 1
infection 12, 19
Dermatophytosis 1, 5, 7, 8t, 11, 16, 43
chronic 1, 4, 11f
current trends of 1
epidemiological studies of 3t
management of 67
recalcitrant 44
recurrent 4
Dermoscopy 20
Diabetes mellitus 35, 38, 45
Distal lateral subungual onychomycosis 19
Drug
interactions 59
resistance 84
E
Eberconazole 69
Echinocandins 52, 53, 60, 63
Econazole 69, 72
Efinaconazole 69
Electrolyte abnormalities 55
Epidermophyton floccosum 19
Erythematous papules, margin of 48f
Estrogen 35
F
Favus 17
Fenticonazole 69
Finger nail involvement 77
Fixed drug eruption 75
Fluconazole 36, 40, 52, 57, 63, 64, 69, 75, 78, 81, 82, 84
single dose 84
Flucytosine 53, 61
Fungal
culture 18
nail infections 19
Fungi 33
G
Gastrointestinal adverse events 55, 62
Glabrous dermatophytosis 3
Glans penis, inflammation of 37
Griseofulvin 52, 53, 61, 75, 80, 81
H
Hailey–Hailey disease 12
Hair 8
Hamycin 54
Headache 55
Heart failure, congestive 75
Hepatic dysfunction 82
Hepatotoxicity 62
Human immunodeficiency virus 45
Hydroxypyridinones 70
Hyperkeratotic lesions 71
Hyperpigmentation 23f, 29f
Hypersensitivity 57
Hypopigmentation 25f
I
Imidazoles 52, 56, 69, 72
Immunity, cell-mediated 44
Incognito 45
Indian Association of Dermatologists, Venereologists and Leprologists Task Force against Recalcitrant Tinea 67
Indian Expert Forum Consensus Group 67
Interdigital tinea pedis 15f
Iodoquinol 53
Isoconazole 72
Itching 34
Itraconazole 40, 52, 58, 64, 74, 77, 81, 82, 84
K
Keratinophilic fungi 1
Keratolytics, topical 72
Kerion 17
Ketoconazole 52, 57, 69, 72, 84
absorption of 57
L
Lacquer preparations 71
Lactation 68
Lichenification 28f
Liposomal amphotericin B 52, 55
Liver function test 75
Luliconazole 69
M
Majocchi's granuloma 11
Meatitis 40
Micaceous balanitis 38
Micafungin 52
Miconazole 36, 52, 69, 72
Microsporum
audouinii 46
canis 16
gypseum 9, 46
Mitotic inhibitor 53, 61
Monotherapy 68
topical 73
Morpholines 69
Mucocutaneous candidiasis 33, 58
Multiple site involvement 3
N
Naftifine 69
Nail 8
Naïve infections 68
Nephrotoxicity 55
Newer amphotericin B formulations 55
Nystatin 36, 52, 54, 55
O
Obesity 39
Onychomycosis 8, 71, 73
Oral contraceptives 35
Oral immunosuppressants 45
Oral itraconazole 81
Oxaboroles 70
Oxiconazole 69
P
Pediatric age group 68
Pharmacokinetics 62
Phimosis 38, 40
Pityriasis versicolor
systemic agents for 83
topical agents for 72
Polyene 5254, 70
antibiotics, fungicidal mechanism of 54f
Posaconazole 52, 64
Potassium
hydroxide mount 18, 18f
iodide 53
saturated solution of 53
Pregnancy 35, 68, 81
Pseudoepitheliomatous keratotic 38
Q
Quinoline derivative 53
R
Renal dysfunction 82
Renal function tests 82t
Ringworm infection 7
S
Scaly lesions 71
Sertaconazole 69
Skin 8
diseases 12
rashes 62
Sodium-glucose cotransporter-2 inhibitors, utilization of 35
Soreness 34
Steroids
modified tinea 11, 45, 48f
topical 42
Subacute cutaneous lupus erythematosus 75
SUBA-itraconazole 58
Superficial fungal infections 66, 68, 77
systemic agents for 73
treatment of 66, 67
Systemic antifungal
agents 74t
therapy 76
indications of 73
Systemic lupus erythematosus 13, 75
T
Tavaborole 70
Terbinafine 52, 60, 69, 72, 74, 79, 8183
mechanism of action of 60f
Terconazole 36
Tinea 7, 23f, 25f, 28f, 32f
barbae 8, 18
capitis 8, 16, 18f, 31f, 78, 79, 80
drug of choice for 80
inflammatory 17f
clinical presentations of 7
corporis 2, 3, 8, 9, 11, 12, 7780
et cruris 3
rounded erythematous scaly lesion of 9f
cruris 3, 8, 9, 12, 7780
et corporis 10
intensely itchy patch of 13f
faciei 8, 9, 12, 14f, 46, 7780
healing 29f
incognito 11, 45
treatment of 76
infection 7, 30f, 42
chronic 3
diagnosis of 20
recurrent 3
manuum 8, 9, 16
pedis 8, 14, 15, 73, 7780
progenetica 50f
pseudoimbricata 10, 46, 49f
pubogenetica 47
types of 8t
unguium 8, 19, 20, 77, 78, 79
drug of choice for 79
Tioconazole 36
Tolnaftate 70
Topical antifungal 81
agents 69t
therapy, indications of 68
Topical corticosteroids 42, 43, 47
role of 71
Trachyonychia 19
Triazoles 52, 57, 69
first-generation 57
second-generation 59
Trichophyton
concentricum 10, 46
interdigitale 14, 19, 85
mentagrophytes 2, 3, 9, 45
rubrum 2, 3, 9, 45, 85
tonsurans 46, 85
verrucosum 9
violaceum 9
U
Urinary catheterization 39
Urinary tract infections 57
V
Vaginal discharge 34
Viruses 33
Voriconazole 52, 64
Vulvovaginal candidiasis 34, 35f
treatment of 36
W
Whitfield ointment 70
Wood's lamp examination 17
X
Xerosis dryness 24f
Z
Zinc pyrithione 53
×
Chapter Notes

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Handbook of Fungal Infections
Handbook of Fungal Infections
Editor Kiran V Godse MD PhD FRCP (Glasgow) Professor Department of Dermatology Dr DY Patil Medical College, Navi Mumbai, Maharashtra, India Consultant Dermatologist Apollo Hospital, Navi Mumbai, Maharashtra, India Associate Editor Anant Patil MBBS MD Associate Professor Department of Pharmacology Dr DY Patil Medical College Navi Mumbai, Maharashtra, India Foreword VK Sashindran
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Handbook of Fungal Infections / Kiran V Godse
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Contributors
EDITOR
ASSOCIATE EDITOR
CONTRIBUTING AUTHORS
Foreword
In the last few years, there has been a dramatic increase in the number of chronic superficial fungal infections. Clinicians have to increasingly deal with chronic and recurrent infections. Another challenge is the widespread prevalence of drug-resistant infections. This book has been written expressly for general practitioners. The topics covered in this book include current trends of dermatophytosis in India, clinical presentations of tinea infection, color atlas of typical and atypical tinea infection, pharmacology of antifungal agent, misuse of topical steroids in tinea infections, and treatment guidelines for superficial fungal infections.
Dr Kiran V Godse and Dr Anant Patil have published three books in last 3 years (Urticaria: Interesting Cases, Interesting Cases in Atopic Dermatitis, and Pruritus and Handbook of Urticaria) as a part of the Global Allergy and Asthma European Network (GA2LEN) initiative. All those books have contributions from leading dermatologists from several countries. The simple language, high-quality images, and illuminating tables and charts enhance the quality of the book. I am confident that this book will serve to fulfill a great unmet need of general practitioners.
VK Sashindran MBBS MD DNB
Dean and Professor of Medicine
Dr DY Patil Medical College, Navi Mumbai
Former Professor and HOD Internal Medicine Armed Forces Medical College
Pune, Maharashtra, India
Preface
There has been alarming rise in the prevalence of chronic and recurrent dermatophytosis in India. With rising number and changing patterns, management of chronic and recurrent dermatophytosis may be challenging in many patients. It gives me an immense pleasure to present “Handbook of Fungal Infections” to the readers. The purpose of writing this handbook is to help family physicians, consultant physicians, and postgraduate students of dermatology better understand epidemiology, clinical presentations, and management of dermatophytosis. Experienced and expert authors have contributed chapters in this book. I am sure readers will find this book very useful in the clinical practice, considering its uniqueness in terms of concept and preparation. This reader-friendly handbook contains several clinical images and tables for easy understanding of the topic. I wish to thank the management of DY Patil Hospital, Nerul, Navi Mumbai, Maharashtra, India, for constant support. I also thank Dr Anant Patil for his support in coordinating collating all chapters and helping in the task of writing the book. I also thank my family, Dr Meenal, Dr Gauri, and Atharva for supporting my academics.
Kiran V Godse