Roshan Lall Gupta’s Recent Advances in Surgery (Volume 16) Puneet
INDEX
Page numbers followed by b refer to box, f refer to figure, fc refer to flowchart, and t refer to table.
A
Abdomen
plain X-ray 93
regions 223
reveals encapsulation 171
ultrasonography of 94
Abdominal
carcinomatosis, treatment of 231
compartment syndrome 56
distension 91
lymphadenopathy 179
pain 91, 172
tuberculosis 97, 165
Abemaciclib 292
Ablation
techniques 38
therapies 38, 207
Acetic acid 114
Acid-fast bacilli 172
Acquired immunodeficiency syndrome 172
Actinomycin D 241
Adenocarcinoma 109, 193
risk of 116
Adenosine
deaminase 179
triphosphate 240
Adrenal gland
ipsilateral 204, 205
removal of 205
Adriamycin 5-fluorouracil 273
Agarose gel electrophoresis 175
Alkylating agents 220
American College of Chest Physicians 146
American College of Gastroenterology 116
American Diabetes Association 179
American Joint Committee on Cancer 202
American Society of Clinical Oncology 76, 245, 283
American Society of Colon and Rectal Surgeons 76
Americas Hepato-Pancreato-Biliary Association 30
Amikacin 182
Amyloidosis 199
Anastomotic stricture 90
Anastrozole 286, 288, 290
Anemia 199
Angioembolization 204, 210
bone of 210
role of 208
Angiogenesis 37, 249, 274, 275
Angiosarcoma 246
Anomalous pancreaticobiliary ductal junction 57
Anthracyclines 241, 273, 274
Antiangiogenic agent 245
Antibiogram 53
Anti-epidermal growth factor receptor, case of 244
Antiestrogen
drug 281
type of 292
Antiproliferative activity 274
Antireflux surgery 118
Anti-resorptive action 284
Antiretroviral therapy 182
Antitubercular
drugs 181
treatment 169
Apoptosis 23
Appendiceal mucinous neoplasm 221
Appendiceal origin 219, 233
Appendix 8
Argon
beam coagulator 13
plasma coagulation 119, 121
pumped dye laser 20
Arimidex-nolvadex 288
Aromatic amino acids 115
Aromatization 286
Arterial
hemorrhage 54
oxygen, partial pressure of 48
Arteriovenous fistula 263
Arteriovenous malformation 249, 253, 255, 256
clinical staging system for 254t
rapid progression of 254
therapy of 263
Ascariasis 90
obstruction due to 98
Ascites
high density 177
malignant 230
Ascitic fluid 172
analysis 179
Aspergilloma, cases of complex 152
Aspirin 123
Atezolizumab 275
Atlanta classification 48
Atrial flutter, recurrent 22
Atrial tachycardia 22
multifocal 22
Austrian Breast and Colorectal Cancer Study Group 288
Autofluorescence 115
Autosonix system 16
Axillary lymph node 272
dissection 290
Axitinib 213
B
Bacillus Calmette-Guérin vaccination 173
Back pain, chronic lower 22
Bacteria, mucosal translocation of 92
Bacterial translocation 172
Balloon-diffusing fibers 122
Bannayan-Rilay-Ruvalcaba syndrome 256
Barium meal 169f
Barium studies 176b
Barrett's esophagus 108
advanced imaging for 114
clinical features 110
diagnosis 110
endoscopic image of 111f
epidemiology 108
histological diagnosis 111
management 116
natural history of disease 109
risk factors 109
role of biomarkers 113
screening guidelines for 116
therapy of 117
treatment of 120t
trials 113, 114
Vienna classification for 112t
Basal-like breast cancer 270
Bedaquiline 186
Belmont hyperthermia pump 228f
Bevacizumab 37, 38, 75, 212, 274, 275, 293
Biophysics 5
Bipolar current, effects red area 12f
Bipolar electrosurgery 11
modified 15
Birt-Hogg-Dubé syndrome 194
Bladder catheter 57
Blebectomy for pneumothorax 149
Bleomycin 210, 262
Blood brain barrier 241
Blue rubber bleb nevus syndrome 251, 259
Body and tail lesions 133
Body mass index 109, 116
Bone tumors 24
Bowel
decompression, role of 96
edema 91, 94
hypoperfusion 93
ischemia ensues 91
large 93
obstruction: small and large, clinical features of 92t
small 93
Brachiocephalic vein 156
Brachytherapy 75
BRCA mutant tumors 276
Breast cancer
free interval 288
hormone therapy for 280
antiestrogen therapy in 282
emerging 293
endocrine therapy, used in 286
estrogen exposure as a risk-factor 282
evolution of 281
hormone receptor positivit 283
modalities of 284
resistance to 291
CDK 4/6 inhibitors 292
large proportion of 280
major molecular subtypes of 269t
mammographic diagnosis of 271
molecular classification of 268
progesterone receptors in 283
quadruple-negative 276
resistance protein 241
TNM staging 269
triple-negative 268276
concept of 276
imaging studies 271
immunotherapy 275
natural history of 271
prevalence of 270
prognosis of 272
radiotherapy in 275
surgery in 272
synonymous with basal-like breast cancer 270
targeted therapy in 273
treatment in 272
Breast conserving surgery 272
Breast tumors 281
British Society of Gastroenterology 111
British Thoracic Society 182
Bronchial blocker 150
Bronchogenic cyst 149
Bullectomy 149
C
Cabozantinib 213
Cachexia 199
Cancer
Care Ontario 76
related intestinal obstruction, management of 101
specific mortality 205
specific survival 210
stem cells 244
war on 246
Candida species 53
Capacitive coupling 6
Capecitabine 74, 274, 276
plus oxaliplatin 38
Capillary
arteriovenous malformation 255
lymphatic-arteriovenous malformation 255
lymphaticovenous malformation 255
malformation 249, 252, 254, 255, 256
therapy of 262
Capsule endoscopy 178
Carbohydrate antigen 199 130
Carbon dioxide, partial pressure of 46
Carboplatin 242, 273, 274
versus docetaxel 273
Carcinoembryonic antigen 28, 65, 77
Cardiac defibrillation 3
Cardiac-specific mortality 206
Cardiovascular system 284, 285
Cavitational
fragmentation 17
ultrasonic aspirating device 17
Cecal, management of 100
Cecostomy 104
Cecum, head of 67
Celiac plexus neurolysis 141
Cell adhesion-mediated drug resistance 243
Cell death 24
receptor-ligand-1 244
Central caseous necrosis 180
Central nervous system, metastases 268
Cerebral cavernous malformation 251
Certain familial syndromes 192
Cetuximab 37, 38, 76
multidisciplinary concept 37
Chemical photosensitizer 262
Chemoprevention 123
agents, role of 124
Chemoradiotherapy
after initial chemotherapy 140
neoadjuvant 135, 136, 290
Chemoresistant
cancers, treatment of 246
cells 244
clones 244
Chemotherapy 36
adjuvant intraperitoneal and systemic 229
by killing chemosensitive clones 244
early postoperative intraperitoneal 229
intraoperative HIPEC plus intravenous 229
neoadjuvant intraperitoneal plus intravenous 228
pharmacokinetic properties of 239
Chest wall invasion 150
Chicken intestine 176
Cholangitis 135
incidence of 141
Cholecystectomy 57, 226
Chorioretinopathy 253
Chromoendoscopy 114
Cisplatin 241, 242, 273, 274
Cisplatinum 210, 273
Clinical Outcomes of Surgical Therapy trial 77
Clinical risk score 36
Clonal evolution 244
Clots, removal of 97
Cold spray anesthetics 24
Colectomies 226
Collagen, presence of 115
College of American Pathologists 283
Colo Rectal Endoscopic Stenting trial 73
Colon cancer
adjuvant and neoadjuvant therapy 74
approach to patients with metastatic disease 73
computed tomography of chest 64
differences between right-and left-sided 63t
disseminated to ovaries 229
epidemiology, changing trends 62
involving adjacent organs 229
low anastomotic leak rate in right 71
management of 62
ongoing research impact future practice 78
open versus laparoscopic surgery for 69
preoperative
investigations 63
management 65
role for
positron emission tomography 64
radiation therapy in 75
surgery for 66
surveillance 76
use of monoclonal antibodies 76
Colon head, ascending of 67
Colonic
decompression 104
lesions 171
obstruction 90
resection 74
stenting 101
Colonography 63
Colonoscopic 179
decompression 104
Colonoscopy 223
versus computed tomography colonography 63
Colorectal
cancer 27
investigation to detect 63
metastatic 27
screening down 62
liver metastases 64
defining resectability 30
factors influencing the treatment strategy 30
lesions 28
majority of 27
management of 27
MRI 29f
surgical management of 30
malignancy 90
surgery 98
Compensatory anti-inflammatory response syndrome 46
Confocal laser endomicroscopy 114
probe-based 115
Conglomerate mass 172
Constipation 92
Contrast-enhanced computed tomography 28, 43
Coregulators 282
Corneal burn 21
Cough 199
Coupling
capacitive 9, 10f, 11
direct 9, 9f
C-reactive protein 151
Crohn's disease 90, 97, 102, 169, 178, 183
Cryoablation 119, 207
Cryotherapy 23, 24, 121
uses of 24
Crystal violet 114
Current density 4
Cyclic vomiting syndrome 47
Cyclin-dependent kinase 285, 291
Cyclophosphamide 273
Cystic masses 200
Cystitis 184
Cystoduodenostomy 50
Cystogastrostomy 50
Cytochrome P450 enzymes 241
Cytokeratin 223
Cytoreductive nephrectomy 209, 210
Cytoreductive surgery 220, 223, 225
Cytoreductive surgery and HIPEC
complications of 230
contraindications to 230
indications for the combined treatment 229
role of 231
Cytosponge: trefoil factor-3 113
D
Debulking
procedure 73
surgery 219
Deep vein thromboembolism 66
Dehydrated alcohol 141
Demodulated currents 7
Deoxyribonucleic acid 242
damage repair 242
Depression 286
Diaphragmatic
pinch 110
plication 149
Diatrizoate meglumine 94
Diatrizoate sodium 94
Diffusion weighted images 221
Dihydropyrimidine dehydrogenase 78
Dilated small bowel loops 175
Disease-free survival 288
benefit 74
Disease-specific survival 36
Distal gastrectomy 226
Distal pancreatectomy 138
pancreaticoduodenectomy 54
Diverticulitis 90
DNA crosslinking agents 276
Docetaxel 274
Double balloon enteroscopic 103, 178
Double wall sign 93
Doxorubicin 211, 225, 240, 242, 262
Drug delivery system 78
Drug-eluting beads preloaded with irinotecan 38
Drug resistance
in cancer 239
chemotherapy sensitivity 245
different mechanisms of 240
looking into future 246
mechanisms of 240f
overcoming resistance: challenging present dogmas 245
principles of 239
reaching the moon 246
tumor microenvironment 243
strains 186
tumor subpopulation 240
Drug sensitivity test 173
Ductal carcinoma in situ 285
Duodenal mobilization 100
Duodenojejunostomy 100
Duodenum, head of 67
Dysfunctional apoptosis 240, 243
Dyspepsia, symptoms of 168
Dysphagia detect 116
Dysplasia 111
high-grade 118
indefinite for 119
low-grade 112f, 118
Dyspnea 199
E
Early Breast Cancer Trialists’ Collaborative Group 281
Eastern Cooperative Oncology Group 139
Efavirenz 182
Elective colonic resection 72
Electrocautery 3
Electrolyte imbalance 92
Electrosurgery 2
in laparoscopic applications, use of 13
recent technological advances in 13
use of 7
Electrosurgical
device 9, 17
generator units 4
pencil works 3
Embolization technique 263
Embolotherapy 263
Emesis 91
Emphysema and lung volume reduction surgery 158
Empyema, early stage 152
Enchondroma 256
Endobronchial suction 150
Endocytosis 240
Endogenous biological substances 115
Endometrial carcinoma, risk of 284
Endopelvic fascia 66
Endoprosthesis 22
Endoscopic
ablative therapies 119
biopsy 169
diagnosis 110
mucosal resection 122
resection 122123
retrograde pancreatography 134
submucosal dissection 122123
transgastric and transduodenal drainage 50
ultrasonography 52, 131
ultrasound- fine-needle aspiration 179
Endoscopy 178, 223
findings surveillance 120
Endosuturing 159
Endotracheal intubation, introduction of 149
Endotracheal tube 150
Endovascular treatment 263
Endovenous
laser ablation 260
radiofrequency ablation 260
Energy sources, different 17f
Enhanced recovery after surgery protocols 65
Enteral stents for colonic obstruction 73
Enterobacteriaceae 53
Enterococcus 53
Enterocutaneous fistula 181, 183
Enteroliths 90
Enterovesical fistula 184
Enzyme aromatase, inhibitors of 286
Epidermal growth factor receptor 37, 76, 283
Epigastric pain 110, 130
Epilepsy 255
Epipodophyllotoxins 241
Epirubicin 273
Epithelial
appendix cancer 233
mesenchymal transition to 243
ovarian cancer 234
Epithelioid 233
tubercles 166
variants 234
Eribulin 276
Erlotinib 140, 241, 244
Erythrocyte sedimentation rate 199
Erythropoietin 212
Esophageal
leiomyoma enucleation 149
premalignant lesion 24
Esophagectomies 159
Esophagectomy 117, 149
in esophageal cancer 153
Esophagus 146, 149
Estrogen receptor-mediated
membrane signaling 283
mitochondrial 283
nuclear signaling 283
Estrogen response elements 282
Estrogen synthetase 286
Ethambutol 165, 181, 182
Ethanols 263
Ethylene-vinyl-alcohol-copolymer 263
European Institute of Oncology 269
European Organisation for Research and Treatment of Cancer 37
Everolimus 214, 275
Excimer laser, uses of 21
Exemestane trial 289
Extracellular stroma 243
Extraintestinal structures, obstruction of 55
F
Familial leiomyomatosis 194
Fecal
impaction 90
tagging, use of 64
Fecaluria 184
Fibrin degradation product 47
Fimbrial 8
Finney's strictureplasty 183
Fistulography 184
Flank mass 199
Fludeoxyglucose 131
Fluid resuscitation 95
Fluorescence
in-situ hybridization 175
resonance energy transfer 292
Fluorescent nanoparticles 78
Fluorodeoxyglucose 29f
positron emission tomography 65
Fluorophores 115
differential amounts of 115
Fluoroquinolones 182
Folinic acid plus either irinotecan 36
Follicle stimulating hormone 286
Football sign 93
Forced vital capacity 151
Foreign material 97
Fraction of inspired oxygen 48
Fuhrman's grading 198, 214
Fulguration 5
maximum pause in 5
Fulminant hepatitis 182
Fulvestrant 290
Fundoplication partial 118
G
Gallstone ileus 90
Galvanic current 3
Ganglia 141
Gastric
cancer, recurrent 219
emptying 66
folds, proximal margin of 110
outlet obstruction 168
Gastroduodenal artery 137
Gastroesophageal junction 108
Gastroesophageal reflux disease 108, 116
Gastrointestinal
obstruction 47, 55
tract, mucosal layer of 166
tuberculosis, cases of 180
Gastrojejunostomy 100, 135
Gastroparesis 66
Gefitinib 241, 244
Gelatinous ascites 233
Gemcitabine 134, 135, 140, 210, 211, 273
monotherapy 139
Gene expression pattern 269
Germline mutations 109
Gerota's fascia 204, 205
Gland, tail of 49
Glaucoma 255
Glissonian capsule removal 226
Glomuvenous malformation 251
Glutathione S-transferase 242
Gonadotropin releasing hormone 284
Goose neck deformity 176
Gorham stout syndrome 256
Goserelin 286, 290
Granulomatous ailment, chronic 165
Granulomatous inflammation 166, 177, 180
Greater omentum 220
Ground pad failures 6
Growth factor receptor pathways 291
H
Harmonic scalpel 16
Hartmann's procedure 71, 100, 101
Heineke-Mikulicz technique 183
Hemangioendothelioma 250
Hemangioma 250
Hemangiopericytoma 250
Hematemesis 110
Hematogenous
dissemination 166
spread to lungs 198
Hematoporphyrin derivative 20
Hemidiaphragm
left 226
right 226
Hemiparesis, form of 255
Hemodialysis 192
Hemodynamic instability 183
Hemoptysis 199
Hemorrhagic shock, acute 54
Hemostasis 6, 14
Hepatic parenchyma, sparing partial hepatectomy 32
Hepatic resection, technical aspects of 32
Hepatocellular carcinoma 24
Hepatoduodenal ligament, involvement of 226
Hepatosplenomegaly 177
Hereditary lymphedema, primary 253
Hereditary type papillary 194
Hernia
internal, management of 97
obstructed 96
Holmium laser 20
Holmium:Yag laser 21
Homeobox transcription factor 223
Homogeneous collection 49
Hormone
receptor positive 280, 285
replacement therapy 282
therapeutic agents and clinical usage 285t
therapy
adjuvant 287
neoadjuvant 290
Host immune components 211
Hounsfield units 200
Hour-glass stenosis 176
Human epidermal growth factor receptor 2 268, 284
Human immunodeficiency virus 165
Hyaluronate carboxymethylcellulose 98
Hydro-dissection 21
Hydrophilic nontoxic metabolite conjugates 242
Hydroxy-progesterone caproate 284
Hyperbaric oxygen therapy 97
Hypercalcemia 199
Hyperglycemia 48, 214
Hyperhidrosis 158
Hypersegmentation of barium column 176
Hypertension 192, 199
Hyperthermia 225
induced tissue changes 1
Hyperthermic
intraperitoneal chemotherapy 220, 223
rationale of 225
various techniques of 226
solution 226
Hypertrichosis-lymphedema-telangiectasia 253
Hypocalcemia 48
Hypodense
areas in around organ 177
lesions on portvenous phase 28
Hypofractionated 210
Hypokalemia 92
Hypophosphatemia 214
Hypoplastic deep veins 255
I
Iatrogenic factors 192
Ileocecal 182
region 176, 183
Ileorectal anastomosis 101
Ileostomy 71
Ileotransverse bypass is reserved 71
Imatinib resistance mutation analysis 245
Immune system 244
Immunoglobulin G4 57
Immunohistochemical staining 221, 283
Immunohistochemistry 193
Immunological factors 211
Immunomodulatory properties 211
Immunotherapy 210, 277
strategies, newer 211
Indigo carmine 114
Indocyanine green 159
Infected pancreatic necrosis 52
Inflammation, acute 97
Inflammatory bowel disease 90, 102, 179
Infraclavicular nodes 272
Infrared: near, advantages of 78
Infundibulopelvic 8
Iniparib 274, 275
Insulation failure 7
Insulin-like growth factor 1 283
Intensive care unit 47, 151
Interaortocaval lymph nodes 198
Interferon-gamma release assay 173
Interferons 211
Intergroup Exemestane Study 288
Interleukin-2 211
International Society for the Study of Vascular Anomalies classification 250t
International Society of Urological Pathology 198
International Study Group of Pancreatic Surgery 135
International Union for Cancer Control 202
Interstitial edematous pancreatitis 43
Intestinal
metaplasia 121
obstruction 89, 181
accuracy of diagnosis of 93
causes of 90t
choice of surgical procedures 101
classification of 89
clinical manifestations 91
diagnosis 92
large 92
management of 89, 95
pathophysiology 91
role of laparoscopy in management of 102
signs of 92
small 92
tuberculosis 175
ulcers 181
Intestine
non-viable 97
viable 97
Intra-abdominal adhesions
common causes of 97
grades of 90t
Intra-abdominal free fluid 178
Intracranial components 255
Intractable diarrhea 138
Intramucosal cancer 108, 112, 116
Intraperitoneal chemotherapy
regimens, types of 228
role of 220
use of 220
Intraperitoneal viscera 219
Intratumoral signal intensity 272
Intussusception 90
Invasive ductal carcinoma 285
Inverted umbrella sign 176
Irinotecan 36
Ironoxide nanocrystal contrast agent in MRI 78
Ischemia 23, 24
presence of 92
Isolated and grounded generator system 4
Isoniazid 165, 181, 182
Italian Tamoxifen Anastrozole 88
Ixabepilone 273
J
Japanese Society for Cancer of the Colon and Rectum 67
Jaundice 199
obstructive 134
Jejunal obstruction 55
K
Kinase receptor inhibitor 213
Kirsten rat sarcoma wild-type 38
Klebsiella 53
Klippel-Trenaunay syndrome 255, 256, 259
K-ras 73
Krukenberg tumor 230
L
Lactate dehydrogenase 93, 200
Laparoscopic
necrosectomy 54
procedures 15
surgery 6, 9, 24
oncological safety of 70, 79
use in 5
versus open colon cancer surgery 77
versus robotic surgery 70
Large intestine 10
Laser 18
beam, methods of release of 19
biophysical, principles of 19
generation, method of 18
properties of commonly used 9t
therapy 262
tissue interaction 20
unique properties of 18
Laxatives overuse 103
Letrozole 286, 288, 290
Leucovorin 36, 74
Leukemia 241
Leuprolide 286
Ligasure
instruments 15
vessel sealing system 15
Light Amplification through Stimulated Emission of Radiation 18
Liposomal 273
Liquefactive necrosis 166
Liver
abscess 184
first approach, systemic chemotherapy 32
function test 182
metastases 29f
approach to patient with synchronous 31
oncosurgery management of 32
synchronous versus metachronous 27
synchronously detected 34fc
unresectable, treatment options for 38
parenchyma 38
resection 38
Lobectomy 146, 149, 157, 159
Lobular carcinomas 291
Locoregional therapy 38
Loop colostomy 72
Low-molecular-weight heparins 141, 259
Luminal tumors 273
Lung 149
and breast cancers 241
and diaphragm 146
cancer
early stage 149
resection for 153
video-assisted thoracic surgery 153
volume reduction surgery 149
Lymph node 150
dissection 153, 209
involvement 178
tuberculosis 177
Lymphadenopathy 177
Lymphatic malformation 249, 252, 255, 256, 262
classification of 253b
therapy of 261
Lymphaticovenous malformation 255
Lymphedema 253
choanal atresia 253
distichiasis 253
Lympho-adipose tissue 67, 69
Lymphocyte 151t
Lymphoma 241
Lymphovascular invasion 77, 276
M
Macrocephaly 256
Macrocystic, treatment of 262
Maffucci syndrome 256
Magnetic resonance angiography 253
Malignancies, primary 231
Malignancy 178
spreads 223
Malignant peritoneal mesothelioma 233
Malnourished patients 99
Mantoux test 173
Marshall scoring system, modified 47, 48t
Maryland dissector 9f
Mediastinal biopsies 158
Mediastinal space for thymic surgery 156
Mediastinal tumors, posterior 149, 159
Mediastinum 146, 149
Megestrol acetate 284
Melted extracellular water 1
Memorial Sloan Kettering Cancer Center 36
Menopausal symptoms 286
Mental retardation syndrome 253
Mesenchymal components 249
Mesenteric artery syndrome, superior 90, 99, 130, 132
precipitating factors for 99
radiological criteria for diagnosing 99
surgical procedures 100
Mesenteric ischemia 91
Mesenteric lymph nodes 166
Mesenteric tubercles, multiple 180
Mesenteric vein, superior 67, 130, 137
Mesocolic excision
complete 68f
main component of 67
Mesorectal excision 66
Metabolic complications 48
Metachronous cancer, detect 76
Metachronous lesions 74
Metal
cannula system 12
stent, self-expanding 71, 135
Metaplastic mucosa causes 110
Metastasectomy 204
Metastatic breast cancer 280, 285
hormone therapy for 289
Metastatic colorectal tumor 76
Metastatic lesions 199
Methylation 242
Methylene blue 114
Microarray-based technology 268
Microsatellite instability 74
Microsomal enzymes metabolize 241
Microtubule stabilizer 273
Microvascular invasion 214
Microwave ablation 22
Minimal access retroperitoneal pancreatic necrosectomy 54
Minimally invasive technique 183
Minimally invasive thoracic surgery 146159
benefits of 151, 151b
benign indications for 152
contraindications 150
future prospects in 156
indications for 149
indications for diagnostic 149
indications for therapeutic 149
oncological aspect of 153, 155
principles of 150
technological advances in 158
thymoma for 155
Mitochondria 21
Mitomycin C 225, 228
Molecular
genetics 193
methods 173
subtype 269
Monoclonal
antibodies 212
antibody bevacizumab 76
Monopolar electrosurgery 11
Mucinous tumors 226
Mucosal integrity, loss of 91
Multidrug resistance 239
emergence of 165
Muscle strength 66
Mutation
detected 245
in the signaling pathway 76
of exon 2 76
Myalgias 286
Myasthenia gravis 155
thymectomy for 149
Mycobacteria detection, culture and drug sensitivity 174t
Mycobacterial culture 173
Mycobacterium tuberculosis 172
Myeloid leukemia, chronic 244
Myeloma cell 243
Myeloma upregulate 241
N
Nab-paclitaxel 134, 274
Nanotechnology 78
Nasogastric tube 91
National Comprehensive Cancer Network 28, 64, 76, 129, 146
National Surgical Adjuvant Breast and Bowel Project 281
Necrotic collection 52f
acute 50
Neodymium-doped:yttrium aluminum garnet 260
Neostigmine 104
Nephron-sparing
kidney cancers prostate cancer 24
surgery versus radical nephrectomy 206
Neuroblastoma RAS 73
Nicotinamide adenine dinucleotide hydrate 115
Nitroimidazole-oxazine PA-824 185, 186
Nonhomologous end joining pathway 242
Nonmetastatic hepatic dysfunction 199
Nonne-Milroy syndrome 253
Non-nucleoside reverse transcriptase inhibitor 182
Nonsteroidal anti-inflammatory drugs 110
Nuclear pleomorphism 268
Nuclear scintigraphy 200, 202
Nucleic acid amplification tests 173
Nucleotide excision repair 242
pathway 242
O
Obesity 192
Obstructed colonic cancer, management of 70
Odynophagia 110
Olaparib 274, 275
Oligometastatic disease 210
presence of 138
Oncotype-Dx 289
Ophthalmologic lasers, hallmark of 18
Oral contraceptive pills 282
Organ dysfunction syndrome, multiple 46, 47
risk of 46
Organ failure
assessment, sequential 47
multiple 44
persistent 46, 47
transient 46, 47
Orthopedic surgery 22
Osteolytic metastatic bone 199
Osteoporosis 286
Ovarian
cancer, recurrent 230
function suppression 287, 288
ligaments 8
tumors 101
Oxaliplatin 36, 75, 228, 273
P
Paclitaxel 274, 275
Pain 199
Pain and infection 252
Palbociclib 292
Palliative
care 140
interventions 204
measures, specific 140
Pancreas
divisum interfering 57
head of 49, 67
protocol 130
Pancreatic
abscess 47, 52
ascites 56
cancer, advanced 129
cancer, borderline resectable 129141
definitions 131
evaluation and workup 130
principles of management 134
prognosis 142
cancer, locally advanced 132f, 138, 139
cancer, surgical techniques for 138
fistula 138
necrosis 51f
parenchymal necrosis, presence of 44
pleural effusion 56
pseudocyst 49, 50f
resection 54
sphincterotomy 57
stump 138
tests 57
Pancreaticoduodenal arteries 54
Pancreaticoduodenectomy 138, 172
specimen 137f
Pancreatitis, acute 43
classification of 45fc
complications of 43, 46, 47t
phases of 45
recurrent 57
causes of 57
severity, classification of 44
severity, grades of 44t
systemic complications of 47
types of 43
Pancreatitis edematous 44
Pancreatitis, mild acute 44
Pancreatitis, moderately severe acute 44
Pancreatitis necrotizing 43
Pancreatitis, severe acute 44
Pancreatoduodenectomy 138
Panitumumab 37, 38, 76
Para-aminosalicylic acid 165
Paracolic gutters, left and right 226
Paraneoplastic
phenomenon 199
syndromes 199
Parathyroid hormone-like peptides 199
Parenchymal
dissection 21
organs 21
Parkes Weber syndrome 256
Partial nephrectomy 206, 207
Paustian's criteria 181
Pazopanib 213
Peak hepatic enhancement 130
Pegylated variety 273
Pembrolizumab 275
Peptide growth factor mediated 283
Percutaneous
catheter drainage 53
microwave ablation 23
sclerotherapy 264
Perianal fistulae 181, 184
Pericardium 233
Periduodenal lymph nodes 168
Perinephric
tissues 204
fat 205
Peripancreatic
arteries 130
collection 55f
fluid collection, acute 48, 49
necrotic 51
Perirenal hematomas 199
Peritoneal
adhesion 89
carcinomatosis 219
assessment of 224f
cases with mucinous 223
colorectal cancer 231
detection 221, 222t
diagnosis 220
gastric cancer 232
management of 223
ovarian cancer of 234
prevent of 232
staging, disease burden 223
cavity 57, 99
epithelial implants, multifocal 233
malignant mesothelioma, treatment choice for 234
mesothelioma 229, 233, 234
metastasis 74, 220
mucinous carcinomatosis 233
pseudomyxoma 229
sarcomatosis 230
Peritoneum 166, 233
Peritonitis 97
Peritumoral inflammation 72
Phenothiazines 103
Phosphoinositide 3-kinase inhibitors 293
Photoablative 19
Photochemical 20
Photodynamic therapy 119, 122, 262
Photokeratitis 21
Photothermal 20
Picibanil 262
Pinocytosis 240
Platelet-derived growth factor 212, 274
Platinum-based primary intraperitoneal chemotherapy 234
Pleura 149
serosal layer of 233
Pleural
biopsy 149
effusion 56, 158
Pleurodesis 149
Pneumaturia 184
Pneumonectomy 149
Pneumonitis 214
Poly (ADP-ribose) polymerase inhibitors 274
Poly-adenosine diphosphate 243
Polycythemia 199
account of 199
Polymerase chain reaction 175, 179
Porfimer sodium 122
Porphyrins 115
Portal fashion 147
Portal vein 130, 132, 133, 137
Portal venous phase 28, 130
Port-wine stains 254
Positron-emission tomography 77, 131, 222
role of 202
Postmenopausal
obesity, case of 282
women 288
Potassium 183
titanyl phosphate lasers 262
Potent multikinase inhibitor 274
Pouch of Douglas 226
Power cutting 17
Premenopausal women 288
Procarbazine 242
Progestins 284
like medroxy-progesterone acetate 284
Progressive disease, supportive care for 140
Prostaglandins 199
Prosurvival signals, external 240
Protective stoma, use of 71
Protein
calorie malnutrition 48
correlates 292
denaturation 15
Proteus syndrome 256, 261
Proton pump inhibitors, use of 109
Pseudoaneurysm-associated bleeding 54
Pseudocapsule 193
Pseudocysts 49, 50
contents of 52
pancreatic 54
reports of 56
Pseudomyxoma peritonei 219, 227f, 233
Pseudo-obstruction 103
causes of 103
old age 90
Pulmonary
aspergilloma 152
biopsies 158
fibrosis 262
nodules, resection of 158
Pulse mode 18
Pulsed current 3
Pure coagulation current 6
Purified protein derivative 173
Purse-string stenosis 176
Purtscher's retinopathy resulting 57
Purulent form 172
Pyogenic granuloma 250
Pyrazinamide 181, 182
Pyrexia 199
R
Radiation
in neoadjuvant setting 136
proctitis 90
therapy, intensity modulated 75
Radical nephrectomy 204, 206, 206f, 210
part of 205
procedure 205
Radical total pancreaticosplenectomy 137f
Radioembolization 28
Radiofrequency
ablation 22, 38, 119, 207, 208
current 2
output 14
Radioisotope renogram 202
Radiotherapy 139
Radiotherapy, conventional 210
versus stereotactic 136
Ranson's criteria 43
Rapamycin 275
mammalian target of 213, 274, 275, 291
mechanistic target of 259
Rectal cancer 29f
Regional lymphadenopathy 200
Renal
cell carcinoma 190, 206, 209f
bilateral 201f
clinical features 198
computed tomography 200
imaging 200
investigations 202
laboratory findings 200
magnetic resonance imaging 201
physical examination 199
epidemiology 191
etiology 191
familial subtypes 194t
grading systems 198t
histological, subtypes of 196t
immunotherapy 211
management 204
pathology 193
pulmonary metastases in 203f
recent advances in 190
role of genetic factors 192
staging 202
systemic therapy for advanced/metastatic 210
targeted therapies 212
TNM staging 203
treatment of
advanced 208, 209
localized 205
disease, end-stage 192
failure, acute 47
parenchyma 193
tumors 200
vein 204
Retinal damage 21
Retinoblastoma 24
Retrograde transvenous embolization technique 263
Retroperitoneal
hematoma 54, 103
lymph nodes 172
Retroperitoneoscopic approaches 207
Retroperitoneum 54, 57
Rhabdoid morphology 198
Ribociclib's 292
Ribose polymerase 243
Rifampicin 165, 181, 182
resistance 175
Rigler's sign 93
Robotic thoracic surgery 159
Roux-en-Y cystojejunostomy 50
S
Sarcomatoid
components 211
elements 214
variants 210
Schobinger classification 263
Sclerotherapy 259, 262
principle of 260
Segmentectomy 149, 157, 159
Selective ER
degraders 284
modulators 284
Semiclosed technique 226
Sentinel lymph node 290
Seprafilm 98
Serosal surfaces 219
Sertraline 246
Serum amino transferases 130
Servelle-Martorell syndrome 256
Short bowel syndrome 183
Sigmoid colectomy, specimen of 32
Sigmoid lesion, synchronous resection of 33
Sigmoid volvulus 100
Sigmoidopexy 100
Single strand DNA breast 274
Sinusoidal fashion 3
Sirolimus 261
role of 259
Skeletal pain 199
Skin
discoloration 252
malignancy 21
Small bowel
disease, extent of 225
feces sign 95
obstruction 89, 90
tuberculosis 182
Smart electrode technology 14
Smoking, cessation of 192
Sodium 183
Soft tissue densities 177
Sorafenib 212, 274, 275
Sparking and arcing 9
Spinal
deformity 99
metastatic sites 210
trauma 99
Spindle cell hemangioma 256
Splenectomy 55, 138, 226
Splenic
artery 54
artery embolization 55
vein thrombosis 54, 55
Spontaneous pneumothorax 158
Squamocolumnar junction 110
Staphylococcus aureus 53
Statins 123
Stauffer's syndrome 199
Stem cell transplantation 211
Stereotactic
body radiation therapy 38, 74, 140, 210
radiosurgery 210
Sternotomy, median 156
Steroid hormone 17-beta-estradiol 281
Stierlin sign 176
Stoma related complications 76
Stromal
cells 243
elements 282
Sturge-Weber syndrome 254, 256
Submucosa
cancer 112
lymphoid tissue 166
Subtotal colectomy
limitations with 72
versus segmental colectomy 72
Succinate dehydrogenase 194
Suck cut technique 122
Sulfotransferases 242
Sunitinib 213, 241, 274, 275
Supraclavicular
lymphadenopathy 200
tachycardia 22
Surgery
anterior mediastinal masses for 149
locally advanced pancreatic cancer for 140
sexual problems, after 76
Surgical
glove injury 6
practice, energy sources in 1
technique, good 97
Systemic chemotherapy 38
Systemic inflammatory response syndrome 45, 46b, 47
Systemic platinum-taxanes chemotherapy 234
T
Talc pleurodesis 158
Tamoxifen 281, 286, 287, 288, 289, 290, 292
Taxane-anthracycline combination 277
Taxanes 273
Temozolamide 242, 274
Temsirolimus 214
Testicular cancer 192
Thermal
injury 8
tissue effects 1
Thioridazine 246
Thoracolaparoscopic esophagectomy 153
Thoracoscopic
instruments 148
pericardial window 149
surgery 147
and video-assisted thoracic surgery, difference 147
equipment for 148
equipment required for 148
multiportal 157
ports for 147f
sympathectomy for hyperhidrosis 149
thymectomy 155
Thoracotomy
group 154
procedures 151
Thrombocytopenia 214
Thromboembolism 259
Thrombophlebitis, recurrent 255
Thymectomy 159
for thymoma 153
in myasthenic patients 158
Thymic horns 156
Thymidine phosphorylase 78, 242
Thymoma 149
early stage 156
Tissue
changes, temperature determined 2
injury 7
distal site 8f
during adhesionolysis 8f
management system 14
Tobacco consumption 192
Toldt's fascia, lifting of 68f
Topoisomerase II inhibitors 242
Topotecan 274
Total pancreatectomy 138
Transabdominal ultrasonography 43, 130
Transarterial chemoembolization 38
Transcriptase-polymerase chain reaction 283
Transmembrane domain exists 241
Transmembrane proteins 282
Transoral endoscopy 110
Trastuzumab monoclonal antibody therapy 272
Trefoil factor-3 113
Tricyclic antidepressants 103
Trocar cannula units 148
Tubercular ascitis 179
Tuberculin test 173
Tuberculosis 102, 165
abdominal 97, 165185
clinical presentation of 167t
criteria for diagnosis of 181
from Crohn's disease 170t
histopathology in 180
laboratory diagnosis 172
management of 181
pathophysiology of 166
role of
diagnostic laparoscopy 180
surgery 182
sites involvement of 166
colorectal 170
current diagnostic methods for 174t
esophageal 168
extrapulmonary 175
risk of 166
gastroduodenal 168, 182
in Asia and Africa 90
jejunal and ileocecal 168
lymph node 172
new modalities in management of 185t
peritoneal 171
solid organs of 172, 177
Tuberous sclerosis 192
Tubule formation 268
Tufted angioma 250
Tumor
borderline resectable 132, 133
cells 225
with sarcomatoid 198
central 38
derived 1,25-dihydroxycholecalciferol 199
detecting synchronous 65
extends 204
giant cells 198
heterogeneity 240, 244
locally advanced 138
marker 130, 221
microenvironment 244
non-metastatic 131
polyps 65
primary 31, 32
resection of 22
rupture primary resection 230
small 65
thrombus 198
unresectable 131
venous thrombus 200
Tunica vaginalis testi 233
Tyrosine kinase 275, 277
Tyrosine kinase inhibitor 213, 244, 274
U
UK Special Interest Group in Gastrointestinal and Abdominal Radiology 63
Ulcerohypertrophic variety 169
Ultracision, high power system 16
Ultracold liquid causes 23
Ultrasonic
cutting 16
dissectors 15
energy 15
Ultrasound, physics of 15
Ultrasurgical hook 16
Ureteral obstruction 199
Ureters 55
Urethral sling, mid 37
Uridine 5’-diphospho glucuronosyltransferases 242
US Food and Drug Administration 292
Uterosacral 8
V
Vagal-sparing esophagectomy 119
Vaginal prolapse repair 37
Valvulae conniventes 93
Vapor pulse coagulation 14
Vascular endothelial growth factor 76, 273
development of 212
pathway antagonists 212
Vascular malformation 249, 250, 251f, 264
associated with other anomalies 256b
chest wall involvement in 258f
classification of 250, 251b
combined therapy 255, 255b
diagnosis tool 256, 257
extensive involvement of trunk 251f
major vessels of 255
therapy of fast-flow 263
treatment 258
endovenous intervention 260
laser excision 260
medical management 259
sclerotherapy 259
surgical excision 260
Vascular organ 172
Vascular tumor 249, 250
Vasculogenesis 249
Veliparib 274, 275
Vena cava, inferior 55, 198, 199, 202, 209
Vena cavography, inferior 202
Venous
malformation 249, 250, 255, 256
elbow region of 261
therapy of 258
phase contrast-enhanced CT 28f
thromboembolism 141
tumor thrombus management of 208
Ventricular arrhythmias, types of 22
Video-assisted
fistula therapy 184
retroperitoneal debridement 54
thoracic surgery 146, 148
augmented reality in 159
instruments 148f
limitations of 151
ports 148f
three-dimensional 158
two-dimensional 158
uniportal 156
versus open thoracotomy, benefits of 150
Vienna classification 111
Vinblastine 210, 240
Vinca alkaloids 241
Vinorelbine 276
Virgin abdomen 96
Visceral organ tuberculosis 184
Voltage waveform 12
Volumetric laser endomicroscopy 115
Volvulus 90
Vomiting 91
von Hippel-Lindau disease 192194, 212
W
Walled-off necrosis 52
Water jet dissection, high-velocity 21
Whirl sign 95
Wilms tumor 191, 192
World Health Organization 155, 165, 193
Wound protector 148f
X
Xpert M. tuberculosis 175
Y
Yttrium-90
microspheres 75
selective internal radiotherapy 38
×
Chapter Notes

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