Prelims

INDEX

ABCDEFGHIJKLMNOPQRSTUVWXYZ

Page numbers followed by f refer to figure, fc refer to flowchart, and t refer to table.

Abdomen, pigmentary lines of 125f

Abrasions 1628

Abrocitinib 2049

Abscess 74, 1688, 1688f, 1694

labial 460f

metastatic 1738

perianal 1689

Absidia 1871

Absorption, curves of 2074f

Abtropfung 1501

Acanthamoeba 461, 1885, 1886

Acanthaster planci 1617

Acantholysis, suprabasilar 84f

Acantholytic epidermolysis bullosa simplex 287, 644

Acanthosis 74, 537f

nigricans 922, 933, 933t, 934f, 1085, 1138

verrucous 502f

Acatalasemia 1332

Achilles tendon 262f

Acid beta-glucosidase 904

Acidemia 876

methylmalonic 875, 1446

propionic 876, 1446

Acidosis, metabolic 2035

Aciduria

erythematous methylmalonic 876f

methylmalonic 876

mevalonic 836

propionic 876

Acne 33, 764, 840, 1226, 1236f, 1237, 1243

classification of 1224t

conglobata 1237, 1237f

corticosteroids-induced 1242f

cosmetica 1241

cysts 1243f

differential diagnosis of 1229t

excoriée 1238, 1239f

formulation, topical 599f

free nevus 401

fulminans 1224, 1237, 1237f

hormonal therapy for 932

infantile 371f, 1236

inflammatory 1229f

keloidalis 1040f

nuchae 1039, 1203

midchildhood 1236

neonatal 138, 138f, 1235

neonatorum 138

nodular 1243f

occupational 1241

preadolescent 1236

propionibacterium 33, 858, 1118, 1202, 1225

severe 1228f

syndrome 764, 841f

variants 1235

venenata 1241

vulgaris 1230, 2052

Acneiform

eruptions 1671

papules 1866

Acquired immunodeficiency syndrome 458, 459t, 1015, 1278, 1381, 1571, 1765, 1772, 1824, 1923, 1989

Acral erythema, chemotherapy-induced 698, 698f

Acral erythemas 694

Acral hyperkeratosis, focal 275

Acral peeling skin syndrome 240, 643, 645f

Acral pseudolymphomatous angiokeratoma 1005, 1470

Acral skin 17f

Acrocyanosis 123, 694

Acrodermatitis 876

chronica atrophicans 1056, 1717

dysmetabolica 875, 875t

enteropathica 147f, 630, 878, 883, 884f

Acro-dermato-ungual-lacrimal-tooth syndrome 304, 305, 316, 317, 319

Acrodynia 697

Acrokeratoelastoidosis 275, 275f

Acromelanosis 125f

albo-punctata 1157

Acropustulosis 141, 141f

Actinic cheilitis 1552f

Actinic keratoses 1551, 1552, 1552f

Actinic prurigo 1643, 1643f, 1998

Actinodendron plumosum 1619

Actinomadura madurae 1856

Actinomyces 1705, 1709

israelii 1705

pelletieri 1856

Actinomycetales 1736, 1747

Actinomycosis 1705

Actinomycotic mycetoma 1857

Activated partial thromboplastin time 734

Acupuncture 2101

Acute allergic contact dermatitis 600f

Acute cutaneous lupus erythematosus 429, 784

Acute graft-versus-host disease 463, 465f, 466f, 467f, 469, 727

stages of 466t

Acute respiratory distress syndrome 1862

Acyl hydrocarbon receptor 508

Acylceramides 210f

Adalimumab 515, 2044

Adams-Oliver syndrome 184f, 374, 1169, 1169f

Addison's disease 371, 920, 921, 925, 925f, 1057, 1128, 1139, 1138, 1336, 2040

Adenine 56

Adeno-associated virus 2116, 2117

Adenomas, sebaceous 316

Adenomatous polyposis

coli 961

familial 956, 961, 1526, 1586

Adenosine deaminase 448, 755, 842, 847, 2122

deficiency of 699, 842, 842f

Adenosine triphosphate 322, 889, 1062, 1151

Adenosyl-cobalamin cofactor 875

Adenovirus 1446, 1762f, 1767, 1773, 2116, 2117

Adhesives 2070

plaster bandage 600f

Adipocytes

mature 1532f

phagocytosis of 1084f

Adipose lobules, panniculitis involving 1084f

Adipose tissue, tumors of 1538

Adjunctive therapy 590

Adnexae, tumors of 1479

Adrenal disorders 925

Adrenal gland 930

Adrenal insufficiency, primary 1138

Adrenal steroid biosynthesis 931f

Adrenarche, premature 931

Adrenocortical dysplasia homolog 344

Adrenoleukodystrophy 1139

Adverse drug reactions 156, 1664, 1675

classification of 1665t

Advisory Committee on Immunization Practices 1763

Aedes aegypti 171, 1767, 1768

Aedes albopictus 171, 1767, 1768

Aeromonas hydrophila 1614, 1616, 1619, 1620, 1697

African Programme for Onchocerciasis Control 1888

Agalsidase

alpha 904

beta 904

Agammaglobulinemia 444

Agranulocytosis, history of 2054

Aicardi–Goutières syndrome 170t, 695, 745, 841, 847, 1599

Air bag injury 1605

Airway involvement 1363

Alabaster pallor 918f

Alae nasi, hypoplastic 296

Alagille syndrome 963, 964

Alanine

aminotransferase 498

transaminase 1670, 1787, 2054

Albicans 1323

Albinism 1100, 1582

classical oculocutaneous 1098t

deafness syndrome 1154

oculocutaneous 373, 1098, 1098f, 1099–1101

Albright's hereditary osteodystrophy 59, 941, 1022, 1026, 1028f, 1544

Alcoholism 1691

Alcyonidium

diaphanum 1618

hirsutum 1618

Alemtuzumab 776

Alezzandrini syndrome 1101

Alkaline phosphatase 1670

Alkaptonuria 874

Allelic didymosis 385t

Allelic heterogeneity 61

Allelic twin-spotting phenomenon 1152

Allergen

immunotherapy 591

investigating 601t

Allergic contact dermatitis 43, 49, 107, 598, 600f, 601t, 604f, 605f, 620, 956, 1315f, 2000, 2066f

diffuse 604f

signs of 2066f

symptoms of 2066f

Allergies 239

multiple 289, 289f

Allescheria 1838

Alloknesis promotes 1975

All-trans-retinoic acid 761, 1980, 1981

Allylamines 1987, 1988

Aloe ferox 2098

Aloe vera 2097, 2098

Alopecia 74, 235f, 299, 945, 1167f, 1169f, 1177f, 1631

areata 70, 795, 1187, 1265, 1266, 1266f, 1284, 2004, 2023

congenital 292, 1165

early-onset 1165

lipedematous 1169

mucinosa 910, 1204

neonatal 128f, 1168

nonscarring 1185

patchy 240f, 1168, 1922f

permanent scarring 1828f

postnatal 127

postoperative 1193f

pressure induced 1193, 1610, 1610f

temporal triangular 1168f

temporary diffuse 1186f

totalis 369

traction 1193, 1194f

traumatic 1193

Alpha-1-antitrypsin 969

deficiency 965, 969, 1082, 2122

Alpha-2-antiplasmin 738

Alpha-galactosidase A 903, 904

deficiency 903

Alpha-hydroxy acids 1974

Alpha-interferon 1185

Alpha-linolenic acid 881

Alternaria 1278

Ambiguous genitalia 932f

Amblyomma

americanum 1652

maculatum 1715

Ambras syndrome 1177, 1178f

Amebiasis

disseminated free-living 1886

free-living 1885

neurological free-living 1886

Amebic meningoencephalitis, primary 1885

Amelanotic melanoma 1563

American Academy of Dermatology Guidelines 2031

American Academy of Pediatrics 496, 1763, 1903, 1971

American College of Rheumatology 812, 816f

Amino acid disorders 871

Aminoaciduria 622f

Aminoimidazole-4-carboxamide ribonucleotide 2029

Aminolevulinic acid 897, 1998, 2004

Amniocentesis 153

Amniotic band sequence 186

Amoxicillin 1671f

Amphotericin B 1851, 1987

lipid formulations of 1851

Amplitude modulation 2090

Amputees reactions 1612

Amyloid 912

A 913

light-chain 912, 913

Amyloidosis 912, 913f

classification of 913t

primary 912, 1525

Anagen effluvium 1187

Anal warts, external 1953

Anaphylatoxin 32, 36

Anaphylaxis 707

Anaplasma phagocytophilum 1716

Anaplasmosis, granulocytic 1652

Anaplastic large cell lymphoma 1464f

primary cutaneous 1463

Ancillary diagnostic methods 1562

Ancylostoma

braziliense 1889

caninum 1887

Androgenetic alopecia 1197, 1198f

Androgens 925, 929

excess

causes of 929t

disorders of 929

peripheral metabolism of 931

Androstenedione 930

Anemone stings 1619

Anergic leishmaniasis 1861

Anergy 40

Anesthesia 2105

general 2105

local 2105

Anesthetics 2105

local

injectable 2105

noninjectable 2105

topical noninjectable 2105

Anetoderma 155, 155f, 1048, 1055, 1441f

primary 1056

secondary 1056, 1056f, 1057t

Anetodermic pilomatricoma 1480f

Aneurysms 404

arterial 769

Angelman syndrome 373, 1101

Angiodysplasia 404

Angioedema 74, 702, 705, 711

acquired 712

hereditary 427, 430, 702, 712

Angioendothelioma

endovascular papillary 1379

papillary intralymphatic 1348, 1379

Angiofibroma 1519f

cutaneous 1519

Angiography 1390

Angiokeratoma 1420, 1421f

circumscriptum 1421

corporis diffusum 903, 1421

Angioleiomyoma 1541

Angiolipoma 1540

Angiolymphoid hyperplasia 1007, 1008, 1009f, 1378

Angioma, tufted 741, 1183, 1349, 1350, 1350f, 1376, 1377f

Angiosarcoma 1382

Angiotensin-converting enzyme 703, 989, 996, 1006, 1668, 1808, 2028

Angora hair nevus syndrome 404

Angular cheilitis 1313

Anhidrotic ectodermal dysplasia 1291

Ankyloblepharon 317f

ectodermal

defects 219, 305, 316, 317f

dysplasia 270

Ankylosing spondylitis 820

juvenile 820, 826

Annular elastolytic giant cell granuloma 984, 997

Annular pink-violaceous papules 1007f

Annular urticariform edematous lesions 676f

Anogenital warts 1799, 1953, 1955

Anonychia 1272, 1273f, 1273t, 1291

Anorexia 945

nervosa 1171

cutaneous manifestations of 945t

Antecubital fossa 590

Anterior cervical hypertrichosis 1180, 1180f

Anthralin 508, 1981

Anthrax 1705, 1722

toxin receptor 910

Anti-β2-glycoprotein antibodies 735

Antibiotics 591, 603, 2010, 2041, 2100

oral 1232

topical 1231

Antibody 1010

deficiency 144, 846, 847

mediated diseases 2035

testing 1810

Anticardiolipin 842

Anticoagulant therapy 735

Anticonvulsants 2041

Anti-cyclic citrullinated peptide 822

Anti-desmoglein 663

Antifungals 2018

agents 1988t

griseofulvin 1640

topical 1987

Antigen 47, 49, 50

detection 1947

mapping 91

presentation 39

types of 39f

presenting cells 32, 37, 42, 42f, 465, 724

Anti-gliadin-analogous fusion peptides 678

Antihistamines 590, 1455, 2066f

nonsedating 1975

Anti-inflammatory cytokines 820

Antimalarials 2032, 2034t

drugs, side effects of 2034t

potential uses of 2033t

Anti-malassezia agents 1974

Antimediator drugs, systemic 1456

Anti-melanoma differentiation-associated gene 5 817, 970

Antimicrobial peptides 31, 33, 577

Antimyeloperoxidase 967

Antineoplastic agents 1141

Antineutrophil cytoplasmic antibody 699, 748, 753, 855, 966, 967, 2037

Antinuclear antibody 429, 496, 710, 787, 795, 820, 823, 842, 852, 996, 1049, 1112, 1642, 1674

positive 2011

Antiparasitic agents 1990

Antiphospholipid antibody 788, 1056

syndrome 699, 735, 736f, 787

Antipneumococcal antibodies 313

Antipruritics 1975

Antiretroviral therapy 460

Anti-saccharomyces cerevisiae 957

Antisense oligonucleotides 2116

Antistreptolysin O 1694

Antithrombin deficiency 734

Anti-tissue transglutaminase 960

Antitumor cytolytic T-cell activity 1560

Antitumor necrosis factor 436, 854

alpha agents 2042

Antiviral

drug dosages 2010t

topical 1989

Aortic anomalies 1348

Aortic root diameter 1069

Apert syndrome 1243f

Aphthous stomatitis 848, 1325, 2043

major 1317

minor 1317

recurrent 1317, 1318f

Aplaid syndrome 847f

Aplasia cutis 182f, 1169

congenita 181, 184f, 374, 374t

congenital

diagnosis of 181t, 186

management of 186

Aplastic nevus 1169

Apocrine bromhidrosis 1256

Apocrine chromhidrosis 1256

Apocrine glands 21, 21f–23f, 1256

Apocrine miliaria 1256

Apocrine nevus 401

Apocrine sweat glands 23f

diseases of 1250

Apolipoprotein

B 878

C 881

Aponeurotic fibroma 1531, 1531f

Apoptotic cell 31

Apoptotic keratinocytes 533f

Appendages 20

Aquagenic wrinkling 258

Aquaporin 257, 1621

Aqueous crystalline penicillin G 1302

Arachnids 1651

Arboriform vessels 1580f

Arcanobacterium hemolyticum 1778

Arenaviruses 743

Areolar diseases 1257

Argininosuccinate synthetase 875

Arginosuccinic aciduria 1172

Arnica montana 2099

Arnold–Chiari malformation 1054

Arsenic 1622

Artemis, cooperation of 40

Artemisia vulgaris 1633

Arterial capillaries 25f

Arterial catheters 154

Arterial malformations 1387

Arterial tortuosity syndrome 888

Arteriovenous fistula 1347, 1419

Arteriovenous malformation 968, 1347, 1387, 1415, 1417f, 1418t

Arteritis, lymphocytic thrombophilic 700f

Arthralgia 959

Arthritis 825, 827

enthesitis-related 820, 821, 826

juvenile 702

chronic 820

inflammatory 85f, 510

pediatric granulomatous 993

pyogenic 840, 841f

reactive 1326

sexually acquired reactive 1946

systemic juvenile 824f

idiopathic 822

Arthrogryposis 335

Arthropod bites 1649

Arthropod borne diseases 1978

Arylsulfatase

B 908

E 61

Ascher syndrome 1308

Ascorbic acid 742

Ashy dermatosis 1137

Aspartate

aminotransferase 815, 1701t, 2054

transaminase 511, 1670

Aspergillosis 173, 1869, 1870f

allergic bronchopulmonary 775, 1870

Aspergillus 173, 436, 438, 472, 476, 1278, 1851, 1855, 1870, 1987

fumigatus 173

niger 2097

Ataxia-telangiectasia 62, 416, 419f

Atherosclerotic disease 332

Atopic cheilitis 585f

Atopic dermatitis 33, 387f, 450f, 564, 575, 575t, 577, 578t, 580t, 581f–583f, 585, 585f–587f, 589, 599, 605f, 625, 1253, 1642, 1685f, 1785f, 2000, 2002, 2002t, 2019

classical 585f

diagnostic criteria of 579t

diffuse 585f

features supportive of 586t

Atopic disease 775, 2100

Atopic erythroderma 564f

Atopic eyelid eczema 585f

Atopic folliculitis 585f

Atopic pulpitis 585f

Atopobium 1723

Atopy patch test 109

Atrial myxoma 1128

Atrichia 240f, 1166

congenital 1167

diffuse 1165

isolated 1165

Atrophia maculosa varioliformis cutis 1055, 1055f

Atrophic candidiasis, chronic 1324

Atrophic scarring 318f

Atrophic tongue 343f

Atrophoderma 235f, 1048, 2068

follicular 1049, 1050t

idiopathic 1048f

vermiculata 1049, 1050f

Atrophy 74, 1048

Attacks, acute 713

Attention-deficit hyperactivity disorder 215, 575, 1129, 1975

Auricle, pseudocyst of 1494

Auricular chondritis 856f

Auriculotemporal syndrome 694, 694f

Auspitz sign 94

Australian plant melaleuca alternifolia 2096

Austrobilharzia terrigalensis 1618

Autoeczematization 628, 628f

Autoerythrocyte sensitization syndrome 744

Autoimmune blistering diseases 660, 661, 664, 2037, 2038

Autoimmune bullous diseases 660, 682, 2031, 2037

acquired 162

chronic 674

classic 727

Autoimmune bullous skin disorder intensity score 665

Autoimmune connective tissue diseases 695, 736, 2023

Autoimmune disease 368, 795, 822, 2039, 2047

aggregation of 783

pathogenesis of 2049

Autoimmune disorders 371, 718

Autoimmune hematologic abnormalities 854

Autoimmune inflammatory diseases 2041

Autoimmune polyendocrine syndrome 943, 944t

Autoimmune polyendocrinopathy candidiasis-ectodermal dystrophy 421, 422, 942, 1853

Autoimmune polyglandular syndrome 923, 943f

Autoimmune thyroid disease 795

Autoinflammation 144, 847

Autoinflammatory diseases 759, 847

inflammasome-related 35

Autoinflammatory disorders 843

Autoinflammatory panniculitis 839

Autoinflammatory syndrome 706, 768, 835, 838, 840, 840f, 767, 913

OTULIN-related 839

proteasome-associated 843

Autologous serum skin test 110

Autosensitization 628

Autosomal dominant 256, 264, 355, 374, 417, 443, 737, 836, 879, 890, 1016, 1064, 1066, 1071, 1073, 1145, 1306, 1333

disorder 296, 356, 357, 383t

inheritance 58

skin disorders 383t, 396

segmental mosaicism of 382, 383

Autosomal recessive 262, 266, 273, 355, 374, 416, 417, 737, 738, 835, 879, 890, 1015, 1016, 1061, 1064, 1073, 1145, 1333

congenital ichthyosis 204, 210, 211, 219, 220, 222f, 267, 568f, 1167, 1167f, 1253

disorder 348

genodermatosis 285

hypertrichosis 1178

ichthyosis 1168

inheritance 58

junctional epidermolysis bullosa 386f

keratin 643

keratoderma-ichthyosis-deafness syndrome 266

skin disorders, segmental mosaicism of 384

woolly hair 292

Avena sativa 2097

Axillary freckling 352f, 1129f

Azathioprine 474, 514, 593, 789, 858, 956, 2027, 2028f, 2029t

off-label dermatologic uses of 2027t

potential side effects of 2028t

Azithromycin 2016

Bacillary angiomatosis 1722

Bacillus anthracis 1705, 1706

Bacillus Calmette–Guerin 104, 433, 436, 516, 863, 1695, 1705, 1706, 1740, 1780

Bacitracin-polymyxin B ointment 1302

Bacteria 1941

streptomyces 1987

hygroscopicus 1985

Bacterial disease 102

foci of 703

Bacteriological tests 103

Balamuthia 1885, 1886

mandrillaris 1885

Balanitis xerotica obliterans 795

Banal nevus, classic cobblestone pattern of 98f

Bannayan–Riley–Ruvalcaba syndrome 962, 1422

Baricitinib 2049

Barraquer–Simons syndrome 1086

Barsy syndrome 1072

Bart syndrome 374, 642, 649

Bartonella

henselae 472, 1081, 1282

infections 1718

quintana 1723, 1900

Bartonellosis 1721

Bart–Pumphrey syndrome 296

Basal cell 9, 17

carcinoma 315, 340f, 1050, 1482, 1551, 1551f, 1553, 1578–1580, 2004

criteria for 96

dermoscopy of 1553f, 1580f

eruptive 1554f

layer 18f

nevus syndrome 275, 1579, 1580f, 1581t, 1997, 1998, 2004

diagnostic criteria 1582t

vacuolization 533f

Basal epidermolysis bullosa simplex, types of 642

Basal keratinocyte 23, 644

Basaloid follicular hamartoma 1481, 1483, 1484

Basic fibroblast growth factor 486, 1094

Basophilic cells 1480f

Basophils 31, 36

Bathing suit ichthyosis 222

Bazex–Dupré–Christol syndrome 1051, 1051f, 1166, 1166f, 1171, 1172, 1482, 1551, 1553, 1578f, 1582

Bazin erythema induratum 1081

B-cell 46

activation 47

lymphoma

cutaneous 911, 1467, 2047

mature 1469

pseudolymphoma, borrelia associated 1470

receptor 40

Beach worm 1889

Bead and neck surgery 516

Beau's line 683, 973, 1264, 1265f

Becker's melanosis 1131

Becker's nevus 406, 1131, 1132f, 1182, 2084, 1541

syndrome 406, 407f, 1131f, 1132

Beckwith–Wiedemann syndrome 1310, 1310f, 1569

Bedbugs 1914

nymphal stage of 1914f

Bednar's aphthae 150, 151f

Behçet's arteritis 958

Behçet's disease 530, 749, 759, 767, 842, 960, 1081, 1317, 1330f, 2028, 2035, 2043, 2044

extracutaneous features of 769t

neonatal 148

Behçet's syndrome 763, 848, 1318, 1632

Beighton Scale for Joint Hypermobility 1064t

Benadryl 2066f

Benzophenone 1977

Benzoquinone acetic acid 874

Benzoyl peroxide 1230, 1974

Benzyl alcohol 1902, 1990

Benzyl benzoate 1909

Benzylamines 1988

Berardinelli–Seip congenital lipodystrophy 935

Berlin syndrome 1157, 1157t

Bernard–Soulier syndrome 738t

Beta-blockade 1653

Beta-carotene 1644

Beta-catenin gene 1479

Beta-chemokines 32

Beta-defensins 33

Beta-endorphin 1096

Beta-galactosidase deficiency 907

Beta-glucocerebrosidase 904

Beta-glucuronidase 908

Beta-hexosaminidase 36

Beta-human chorionic gonadotropin 2043

Beta-lactam antibiotic 727, 1690

Beta-lipotropic hormone 1096

Betamethasone 2100

Bevacizumab 969

B-glucan 422

B-hydroxy acids 1974

Bier anemic spots 1810f

Bifidobacterium, strains of 2100

Big toenail, congenital malalignment of 1280, 1280f

Bioflavonoids 742

Biopsy 106

Biotin function disorders 888

Biotinidase 875, 888

deficiency 1446

Birbeck granules, racket-shaped 19f

Birth injury 153

Birt–Hogg–Dubé

disease 1985

syndrome 316, 1481, 1588, 2041

Bisphosphate 41

Biting midges 1650

Bjornstad syndrome 1171

Black dot tinea 1828f

Black hairy tongue 1318

Black heel 1612, 1613f

Bladder diverticula 888

Blaschko's linear hypohidrosis 306

Blaschko's lines 235f, 380, 1048, 1107

Blaschkoid segmental hypermelanoses 1132

Blastomyces 106

adhesin 1861

dermatitidis 1861, 2020

Blastomycosis 1861, 1863f

Blau syndrome 843, 845f, 993, 994f, 996f

Bleach baths 591, 591t

Bleeding 1362

disorders 732, 736, 737

acquired 738, 739

Bleomycin chemotherapy 1136f

Blepharitis 889, 1300

Blepharokeratoconjunctivitis 1300

Blister

formation, planes of 639f

hemorrhagic 338f, 642f

Blistering

dactylitis 682, 1692, 1692f

disorders 685

moderate-to-severe 652f

photodermatoses 685

Bloch–Sulzberger syndrome 143, 308

Blood 1461

brain barrier 2122

chemistry 2012

sampling, fetal 153

streaked stools 621, 1692

urea nitrogen 726, 2015, 2034, 2054

vessel endothelium, neutrophilic infiltration of 83f

Bloodsucking mites 1913

Bloody stools 1435

Bloom syndrome 62, 335, 336, 657, 791

Blue nevi 1128, 1510, 1510f

Blue rubber bleb nevus syndrome 745, 1351, 1364, 1412f

Blueberry muffin 173f, 744, 1572, 1925

Blueberry muffin baby, causes of 170t

Blue-light phototherapy 2083

B-lymphocytes 1776

BN syndrome 407

Bockenheimer syndrome 1414

Body fat, redistribution of 927f

Body lice 1904

Body mass index 487, 945

Body surface area 717, 1461, 1670

total 1601

Bohn's nodules 149, 149f, 1313f

Bone

benign tumors of 1540

cyst 406

Ewing tumor of 1573

hypertrophy 406

marrow

failure 323

transplantation 465, 2118, 2119

morphogenetic protein 1031, 1077

ossification, heterotopic 61

proliferations of 1543

Bonnet–Dechaume–Blanc syndromes 1419

Bony trabeculae, eosinophilic 1028f

Böök syndrome 1332

Borago officinalis 2099

Borderline lepromatous 1118, 1747, 1748

leprosy 1749

Borderline tuberculoid 1119, 1747, 1748

leprosy 1749

Borderline vascular tumors 1378

Borrelia 537

afzelii 692

burgdorferi 692, 1049, 1469, 1470, 1716, 1930

garinii 692

infection 1004

recurrentis 1900

Borrelial lymphocytoma 1717

Bote sign 628

Botryomycosis 1691, 1857

Botulinum toxin 1094, 1251

Bowel syndrome, irritable 2100

Bowen's disease 2004

Brachycephaly 370

Bradycardia 919

Braiding

off scalp 2070

on scalp 2070

Brain 266

edema, cytotoxic 1768

tissue 1169, 1182

heterotopic 192

Branched-chain organic acidurias 876

Branchial arch defects 177t

Branchial cleft anomalies 176, 178f

Breast

abscess 1688

hypoplasia, ipsilateral 1132f

tissue, accessory 195

Brill-Zinsser disease 1711t, 1712

Brittle cornea syndrome 1063

Brittle hair 297f, 329

Brittle nails 1268

Broad-band ultraviolet B 507, 1642, 2000

Brocq pseudopelade 2033

Brodalumab 516

Bromhidrosis, eccrine 1253

Bromo-2-nitropropane-1,3-diol 606, 620

Bronchial anastomotic dehiscence 2041

Bronchiolitis, respiratory 847

Bronchogenic cyst 180, 181f

Brooke–Spiegler syndrome 1482, 1985

Brown facial foundation 2069f

Brown pigmentation, diffuse 1506

Brucella 1730

Brucellosis 1730

Brugia malayi 1695, 1887, 1888

Bruises 1626

B-type natriuretic peptide 1811

Bubostomum phlebotomus 1890

Budd–Chiari syndrome 775

Bulbar conjunctiva, lateral 419f

Bulimia nervosa 945

cutaneous manifestations of 945t

Bullae 73

hemorrhagic 796f

Bullosis diabeticorum 685, 939

Bullous dermatitis artefacta 685, 685f

Bullous pemphigoid 640, 661, 668f, 946

antigen 91f, 645

disease 669

Bunyaviruses 743

Bupivacaine 2105

Bureau–Barriere–Thomas syndrome 270

Burgdorf reaction 698

Burkholderia

cepacia 433

mallei 1733

pseudomallei 1733

Burkitt lymphoma 1469

Burning mouth syndrome 1327

Burns 1601, 1629

abusive 1630

electrical 1603, 1604f

first aid of 1603

friction 1605

mimickers of 1630t

Burow's solution 626

Buschke–Ollendorfs syndrome 1034, 1077, 1177f, 1522

Butyrospermum parkii 2069

Café-au-lait 1129

macules 351, 352f, 353f, 355t, 362, 942f, 1127, 1128–1130, 1130t, 2084, 2086f

multiple 1129f

spots 359, 941, 942, 1128

Calcineurin inhibitors 474

topical 507, 508, 589, 607, 1112, 1975, 1984

Calcinosis

cutis 156, 337, 1020, 1023

classification of 1021t, 1026t

diagnosis of 1026t

iatrogenic 1021, 1024

idiopathic 1021, 1023

management of 1025

types of 1027t

familial tumoral 1021, 1025

hyperphosphatemic familial tumoral 1025f

Calciphylaxis 972, 1020, 1021, 1024

Calcipotriol 1982

Calcium 789, 2035

modulating cyclophilin ligand 443

Calendula officinalis 2098

Callus 74, 1611f

Calpastatin gene 239

Calvarial defect 1414f

Calymmatobacterium granulomatis 1943

Camphor 1975

Campylobacter

fetus 1326

jejuni 1326

Cancer

chemoprevention 2052

manifestations of 973

treatments for 1141t

Candida 171, 422, 472, 1282, 1283, 1316, 1323, 1632, 1694, 1695, 1823, 1830, 1850–1852, 1987

albicans 106f, 171, 421, 476, 612, 692, 883, 889, 1698, 1847

diaper dermatitis 619, 619f

esophagitis 1852

infections 1285, 1847

intertrigo 1694

superinfections 444f

Candidiasis 171, 1275f

acute 1323

pseudomembranous 1323

chronic 1324

hyperplastic 1324

congenital 567f, 172f, 1851f

cutaneous 611, 1848, 1849, 1850, 1850t

granulomatous 1850

mucocutaneous 460f

neonatal 171, 1851

systemic 1852

Candle sign 94

Candle syndrome 841, 842, 1085

Caninum 1889

Cantu syndrome 1177

Capillary leak syndrome 464

Capillary lymphatic-venous malformation 1355f, 1395

Capillary malformations 1347, 1350, 1351, 1352f, 1387, 1388, 1389f

arteriovenous malformation syndrome 379, 969, 1364

dermoscopy of 1390f

diffuse 1388, 1392, 1395f, 1450

Capillary nevus, eccrine 402

Capnocytophaga 1662

Caput succedaneum 154

Carbamazepine 1668f

Carbamoyl phosphate synthetase deficiency 875, 876

Carbaryl 1903

Carbon dioxide 1382

lasers 2073

Carbon monoxide 996

Carboxylase deficiency 1281

multiple 888

Carbuncles 1687

Carcinoembryonic antigen 21, 1487

Carcinoid

syndrome 693, 973

tumors 973

Carcinoma

esophageal 272

metastatic 1563

Cardiac anomalies 1348

Cardiac disease 2040

amelioration of 332

Cardiac myxomas 1128

Cardiocutaneous syndrome 288, 288f

Cardiofaciocutaneous syndrome 204, 361, 364

Cardiomyopathy 268

hypertrophic 362

Cardiopulmonary disease 804, 2031

Cardiovascular disease 372, 2039

early 937

Cardiovascular system 1918

Caregiver, role of 2104

Carney complex 1128, 1583, 1584f

diagnostic criteria of 1128t

Carpet tack 1206

Cartilage

benign tumors of 1540

hair hypoplasia syndrome 424

proliferations of 1543

Carvajal–Huerta syndrome 273, 288

Castleman's disease 974

Cat bites 1662

Cataract 335

sectorial 235f

Caterpillars 1651

dermatitis 1651f

Cationic antimicrobial peptides 1683

Cat-scratch disease 1722

Ceftriaxone 2014

Celecoxib 827, 1621

Celiac disease 500, 674, 679, 959, 1316, 1318

Cell

Death

BCL2 associated agonist of 392

subsequent 2120

luminal borders of 23f

membrane 35f

therapy, reported clinical studies of 2118t

Cellular innate inherent immune components 35, 36

Cellulitis 682, 1695, 1695f

bacterial 682

eosinophilic 772

Centella asiatica 1045

Centers for Disease Control and Prevention 1765, 1903, 1924

Centipedes 1651

Central nervous system 122, 164, 183, 229, 311, 355, 404, 406f, 443, 735, 1074, 1130, 1133, 1388, 1439, 1467, 1492, 1503, 1505, 1571, 1628, 1669, 1704, 1772, 1852, 1902, 1918, 2020, 2097, 2122

disease 783

Centruroides 1653

exillicauda 1653

Cephalohematoma 154

Cephalopoda 1617

Cephalosporins 2013, 2014

dosing regimens of 2013t

oral 2013t

potential adverse effects of 2014t

Ceramidase deficiency 908

Ceramide

fatty acid chain of 210f

synthase 210f

Cercarial dermatitis 1617

Cerebral

cavernomas 1387

cavernous malformation 1351

disease 784

dysgenesis 270, 348

Cerebriform

collagenoma 1522, 1523

sebaceous nevus 398f

Cerebro-costo-mandibular syndrome 1543

Cerebro-oculo-facial-skeletal syndrome 335, 340

Cerebrospinal fluid 231, 1707, 1762, 1851, 1886, 1927, 1988, 2009

Cerebrotendinous xanthomatosis 879

Cerebrovascular disease, peripheral 334

Cervical

adenitis syndrome 848, 1325

hypertrichosis, familial 1180

regions, posterior 1766

Cervicitis, mucopurulent 1944

Cervix 1938

Cesioflamea 1510

Cesiomarmorata 1510

Cetirizine 2066f

Ceylonium 1890

Chamomile 2098

Chanarin–Dorfman syndrome 226, 232, 269

Chancre

perimeatal 1919f

tuberculous 1737

Chancroid 1941, 1941f

recommended treatment regimens for 1942t

Charcot–Marie–Tooth disease 331

Chediak–Higashi syndrome 424, 848, 1099, 1101, 1154, 1155, 1156f, 1445

features of 425f

Cheilitis 1314

glandularis 1314, 1314f

Chemical

burns 1605

conjunctivitis 1301

hepatitis 789

injury 155, 1636

artifactual 1637f

Chemokines 36

macrophage-derived 588

Chemotherapy 473, 1560

toxic erythema of 473

Cherry-red papules 1783f

Chest

upper 343f

X-ray 1862

Chevron nails 1265

Cheyletidae 1913

Cheyletiella parasitivorax 1913

Chickenpox 683, 1056f, 1789

enanthem of 1322f

Chikungunya 743, 1767

neonatal 171

virus 171, 1767

Chilblains 1266, 1599, 1599f

lupus

erythematosus 1600f

familial 695, 847

Child abuse 1626

intraoral manifestations of 1631

Child syndrome 233, 234, 236f, 2122

Child's eyelashes, infestation of 1901f

Childhood pemphigus 664

foliaceus 664t, 665

vulgaris 664, 664t

Childhood psoriasis, clinical spectrum of 487t

Children's dermatology life quality index 16, 70

Chime syndrome 241

Chinese herbal medicine 2099, 2100

Chironex fleckeri 1616

Chiropsalmus

quadrigatus 1616

quadrumanus 1616

Chlamydia 104, 528, 2015

associated syndromes 1945, 1946

trachomatis 528, 1326, 1935, 1943, 1944, 1946f, 1956

Chlamydial infections 1950, 1951, 2012

recommended treatment regimens for 1951t

Chloracne 1242

Chlordiazepoxide 2100

Chlorine 2022

Cholangitis, primary biliary 963, 964

Cholesterol

ester storage disease 879

higher total 498

Chondrichthyes 1616

Chondrodysplasia punctate, X-linked dominant 233

Chorionic villus sampling 64, 153, 216

Christ–Siemens–Touraine syndrome 304

Chromate 603

Chromatography-mass spectrometry 877

Chromhidrosis, eccrine 1256

Chrommycetomeosomes 1899f

Chromobacterium violaceum 1614, 1619, 1620

Chromoblastomycosis 1857, 1859, 1860f, 1861

Chromonychia 1276

Chromosomal breakage

analysis 62

syndromes 62

Chromosomal disorder 61, 368

Chromosomes 55, 59f, 1104

Chronic bullous disease 660, 666, 667f, 667t

Chronic cutaneous lupus erythematosus 429, 784

Chronic diseases 790, 815, 825, 2096

management of 2032

Chronic disseminated histoplasmosis 1867

Chronic graft-versus-host disease 344, 465, 467, 468f, 469t, 1552, 2028

Chronic mucocutaneous candidiasis 421, 422, 423f, 1281, 1285, 1285f, 1324, 1848, 1853

subgroups of 421t

Chronic obstructive pulmonary disease 1145, 2051

Chronic suppressive therapy 1959

Chrysanthemum 1901

Churg–Strauss syndrome 753, 754, 967, 2043, 2047

Cicatricial alopecia 311f

Cicatricial pemphigoid 670

Ciclopirox olamine 1988

Cimex lectularius 1914

Circulation 15

Cladophialophora carrionii 1859

Clarithromycin 2016, 2041

spectrum 2016

Clavus 74

Clear cell papulosis 1487, 1488f

Cleft lip 270, 293, 300, 305, 316, 320

syndrome 321f

Cleft palate 266, 270, 293, 300, 305, 316, 319f, 320

syndrome 316, 321f

Cleft syndrome 219

Clindamycin 1231, 1686

Clinodactyly 406

Clobetasol propionate 797

Clostridium difficile 1326, 1729

Clotrimazole 1839, 1987, 2041

Clouston's syndrome 296, 297f, 304, 322, 1043, 1291

Cloves syndrome 1397

Clubbing 1271, 1272t

Clutton's joint 1928

Coagulation cascade 735f

inherited disorders of 737t

Coagulation disorders 2039

Coal tar 1975

preparations 507

Coats plus disease 344

Cobalamin

C defect 1446

metabolism disorders 889

Cobb syndrome 1419

Cocamidopropyl betaine 109, 606

Coccidioides 106, 1862, 1865

immitis 2020

Coccidioidomycosis 1865, 1871

cutaneous 1866f

disseminated 1865

primary 1865

Cockade purpura 752f

Cockayne syndrome 332, 334, 334f, 339, 791, 1168

Coffin–Siris syndrome 1273f

Cogan's syndrome 857

Colchicine 1140, 2034

Colchicum autumnale 2034

Cold

abscess 164f

agglutinins 742, 1598

injury 1637

panniculitis 1081

sores 682

stimulation test 709

urticaria 709

Collagen messenger ribonucleic acid 330

Collagen nevus 1035f

Collagen vascular disease 756, 781

Collagenoma 359f, 1035f

familial cutaneous 1034

Collagenous stroma 1532f

Collarette scales 74

Collodion baby phenotype 1167

Colloid milium 909

Colon cancer, hereditary nonpolyposis 355

Colony-stimulating factors 32

Color adornment products 2065

Coma blisters 685

Combined oral contraceptives 1233

Comedones 1035f, 1227

Common warts 1797, 1798f

dermoscopy of 1798f

Community-acquired methicillin-resistant Staphylococcus aureus 1688, 1690

Complement fixation 1764, 1859

Complement split products 428t

Complete blood count 505, 510, 710, 762, 996, 1461, 2012, 2030, 2054

Complete lymph node dissection 1564

Complex regional pain syndrome 697

Computed tomography 180, 436, 928, 967, 1030, 1360, 1392, 1481, 1670, 1864

Condylactis gigantea 1619

Condyloma acuminatum 1799, 1955f, 1989, 2039

Condylomata lata 1922f

Confetti-like hypopigmentation 360f

Confusion 1660

Congenital alopecia 292, 1165

syndrome 270, 1167

Congenital heart disease 739

diagnosis of 1272t

Congenital melanocytic nevus 100f, 1111f, 1168, 1182, 1182f, 1501, 1503, 1504f, 1505, 1506t, 1556

dermoscopic patterns 1507

syndrome 1503

Conical teeth, eruption of 306f

Conjunctival erythema 722f

Conjunctival telangiectasias 340f

Conjunctivitis 1301, 1302, 1774

allergic 1302

bacterial 1301, 1302

chlamydial 1302

gonococcal 1301, 1937f, 1939

herpetic 1785f

trachoma inclusion 1302

vernal 1302

viral 1302

Connective tissue

diseases 2029, 2037

heritable diseases of 1061

matrix, fibrous 6

nevus 1034, 1077f, 1521, 1522f

fibroblastic 1036f, 1521, 1522, 1523f

Conradi–Hünermann–Happle syndrome 233, 235f, 567

Constitutional mismatch repair deficiency syndrome 354, 1156

Contact allergens 49f, 602

Contact dermatitis 50f, 598, 1315t, 1782

irritant 598

lateral 620f

Contact hypersensitivity 49

elicitation of 50, 50f

induction phase of 49

Contact irritant dermatitis 599f

Contact stomatitis 1314

Contact urticaria 598, 711

immunologic 598

non-immunologic 598

Contiguous gene syndromes 61

Contraception, method of 1944

Conventional systemic therapies 510

Coombs test, negative 736

COPA syndrome 847

Copious fungal hyphae 87f

Copper pennies 1860

Coproporphyria, hereditary 896

Copy number variant analysis 62, 1066

Coral dermatitis 1618

Cord 75

blood 464

transplantation 463

Corneal opacity 2054

Corneal shields 2077f

Corneocyte plasma membrane 210f

Cornification, disorders of 203, 204t, 207t

Cornoid lamellae 298

Coronary artery aneurysm 1811

Coronavirus disease 2019 (COVID-19) 1316, 1807, 1809, 1810f, 1810t

Cortical thymic epithelial cells 40

Corticosteroids 592, 606, 828, 1835f

intralesional 1370

oral 2022t

systemic 723, 804, 1369

topical 503, 588, 589, 1835f, 1972, 1982, 1983t

Corticotropin-releasing hormone 925, 1225

Corynebacterium 1621, 1709

diphtheriae 1708

minutissimum 101, 1709, 1836

tenuis 1709

Cosmetic 1976, 2065, 2066t, 2067t, 2069t

removal 2068

selection 2066

treatment 2065

Costello syndrome 361, 363, 363f

Costimulatory molecule 41f, 42

role of 42f

COVID toes 1809f

Cowden disease 1319, 1985

Cowden syndrome 1422, 1483, 1526, 1546, 1587, 1589t

Coxiella burnetii 1715

Coxsackievirus 622, 683, 684, 1302, 1320, 1774

A 1774

B 818

Crab lice 1904

Cranial fasciitis 1527

Cranial meningoceles 1169, 1182

Cranial radiation therapy 1606

C-reactive protein 739, 762, 801, 822, 823, 835, 855, 1010, 1697, 1810

Creatine kinase 919

Creatine phosphokinase 815, 1026, 1670, 2050

Crest syndrome 803

Crimean-congo virus 743

Crohn's disease 622, 754, 1081, 1318, 1525, 1632, 1943, 2013

cutaneous 611

diagnosis of 769

metastatic 956, 957f

Cross syndrome 1526

Crotalus horridus 1660

Crotamiton 1910

Crotonyl-N-ethyl-O-toluidine 1910

Crust 74

Cryofibrinogenemia 742

Cryogen spray units 2075

Cryoglobulinemia 695, 699, 742, 855t

Cryoglobulinemic vasculitis 2047

Cryoglobulins 1598

Cryoproteinemia 854

Cryopyrin-associated periodic syndrome 35, 702, 835, 837

Cryotherapy 1589

Cryptococcomas 1871

Cryptococcosis 1868

Cryptococcus 439, 106, 1695, 1987

gattii 1868

neoformans 1868, 2020

Cryptorchidism 266, 1037

Ctenocephalides felis 1712

C-type lectin receptors 33

Cupping 1622, 1632

Curly hair-ankyloblepharon-nail dysplasia syndrome 317

Curry–Jones syndrome 1482

Cushing's disease, skin manifestations of 927

Cushing's syndrome 927f, 1208, 1984

Cutaneous anaplastic large cell lymphoma 1463

Cutaneous lymphoid hyperplasia 1004, 1005f

causes of 1004t

Cutaneous lymphoid infiltrates 1004t

Cutaneous mastocytosis 1449

diagnostic criteria for 1452, 1453t

Cutaneous mosaicism 377

mechanisms of 379

Cutaneous tuberculosis 1737

classification of 1737t

peculiarities of 1740

Cutaneovisceral angiomatosis 1364, 1422

Cutibacterium acnes 1225, 2090

Cuticle loss 374

Cutis laxa 1070, 1071t

X-linked 1171

Cutis marmorata 123, 699

physiologic 124f

telangiectatica congenita 374, 1388

Cutis tricolor 384f, 1152, 1152f

parvimaculata 385, 1153f

Cutis verticis gyrata 1040, 1041, 1041f

congenital forms of 1169

Cyanocobalamin 603

Cyclic adenosine monophosphate 942

Cyclic neutropenia 848, 1318, 1324

Cyclists nodules 1612

Cyclooxygenase 2098

inhibitors 1621

Cyclophosphamide 789, 858, 2047

Cyclospora 528

Cyclosporine 512, 592, 626, 848, 858, 1751, 2025, 2026t

drug interactions 2026t

Cylindroma 1484

Cynergy multiplex 2077, 2080

Cyproterone acetate 932

Cyst 75, 1228

blue-brown 1493f

epidermal 1581, 1586f

epidermoid 1479, 1488, 1489f

hemispheric 1489f

lymphomesenteric 1582

multiple epidermal 1582

pilonidal 1493

preauricular 178f

walls 1239

Cystathionine B-synthase 873

Cysteine 351

Cystic fibrosis 258, 884, 965, 1145

Cysticercosis 1892

Cysticercus cellulosae cutis 1892

Cytidine deaminase, activation-induced 444

Cytochrome P450 2009

Cytokine 32, 36

based cellular differentiation 40

genes 2022

proinflammatory 35f, 1037

receptors, classes of 32f

Cytomegalovirus 170, 461, 476, 743, 1325, 1446, 1670, 1722, 2032

infection

acquired 1778

congenital 170f

Cytophagic histiocytic panniculitis 1083

Cytoplasm 18f

eosinophilic 23f

Cytosine 56

Cytosolic glucocorticoid receptor 2022

Cytotoxic T lymphocytes 50, 684

associated antigen 424, 829, 1560

Dabska tumor 1379

Dactylitis 1282, 1282t

Dakin's solution 317

Dapsone 2035, 2036t

hypersensitivity syndrome 2036

potential uses of 2036t

Darier's disease 80, 84f, 241, 242f, 1270f, 1981, 2004

Darier's dyskeratosis follicularis 1269

Darier's nail disease 242f

Darier's sign 94, 94f, 1470

Darier–Gottron syndrome 269

Darier–White disease 241

Dark cells 21

D-dimer 1810, 1811

De novo ceramide pathway enzymes 210f

Deafness 1928

syndrome 1167

Dechaume–Blanc syndrome 1419

Deep fungal infections 1855

Deep perivascular lymphocytic infiltrate 536f

Deep vein thrombosis 733, 787

Dehydroepiandrosterone 929

sulfate 929, 1199, 1225

Delivery system 2073

Delta wing sign 1909f

Demodex 461, 1239, 1241, 1911

folliculorum 1911

mites 1240

Demodicosis 1240, 1241f, 1911, 1912f

Dendritic cells 19, 31, 38, 43, 49f, 476, 784

Dendrocyte medallion hamartoma 1523

Dennie–Morgan sign 586f

Dense-core granules 5

Dental

abnormalities 311f

alveoli 1864

anatomy 1306

lamina cysts 149

Deoxyribonucleic acid 4, 15, 55–58, 166, 210, 287, 332, 416, 429, 447, 655, 718, 1118, 1190, 1263, 1551, 1579, 1623, 1823, 1980, 2089

liposome-complex 2116

probes 1948

replication 57, 58f

single stranded 1768

transcription 56

Derma T cells 2000

Dermacentor variabilis 1652

Dermal aplasia 386

Dermal atrophy 798f

Dermal dendritic cells 38, 50, 598

Dermal duct nevus 402

Dermal epidermal junction 5, 13f, 18, 639

function 23

structure 23

Dermal fibroblasts 2117

Dermal fibroma 1523

Dermal function 23

Dermal granulomas, noninfectious 983

Dermal hypertrophies 1034

Dermal hypoplasia, focal 60, 305, 313, 314f, 1051, 1053f

Dermal inflammation 79f

Dermal melanocytosis 905f, 1133t, 1510

congenital 1133, 1134f

primary circumscribed 1133

Dermal melanoses 1136

Dermal nodule 1530f

Dermal papilla 10, 25f, 81f, 85f, 677f, 1798f, 1802f

edematous 1436f

Dermal structure 23

Dermal telangiectasia 81

Dermanyssus gallinae 1913

Dermatitis 585f, 1621, 2066

acute spongiotic 81f

aquatic 1617

artefacta 1635, 1636f

chronic contact nickel 600f

extensive seborrheic 565f

herpetiformis 85f, 660, 674, 676f

incontinence-associated 614

infective 633, 634f, 634t

interface 1675, 1781

lip-lickers 1240

mild nummular 626f

neglecta 1638, 1638f

nummular 583f, 625, 626f

papillaris capillitii 1039

perianal 961f

periorificial 1240

severe 239, 289, 289f, 586t

streptococcal 585f

Dermatofibroma 1481, 1520, 1521f

Dermatofibrosarcoma protuberans 1567, 1568f, 1861

Dermatologic diseases 2022, 2023, 2041

multiple 2041

Dermatology 2033t, 2036t

Dermatomyofibroma 1481, 1521, 1521f

Dermatomyositis 811, 1020, 1083, 1121, 1262f, 1998

amyopathic 788

juvenile 811, 817, 818, 1121, 1121f

Dermatopathology

basics of 79

pediatric 80

Dermatophilus 1709

Dermatophyte 1823, 1839

infections, nomenclature for 1824f

natural habitat of 1823t

subcutaneous 1839

test media 1829

treatment of 1841

Dermatophytid reaction 628

Dermato-pulmonary syndrome 969

Dermatoscopy, ABCD rule of 97

Dermatosis 1057t, 1283

acute febrile neutrophilic 143, 759

arthritis syndrome 959f

bowel-associated 959

bullous 652, 682, 960

chronic atypical neutrophilic 333, 839, 842

inflammatory 461

neutrophilic 759

paraneoplastic 973

pigmented purpuric 741

syndrome 839

vesicular 144, 145f

Dermis 996f

complex structural organization of 9f

diseases of 981

reticular 24f

superficial 79f

Dermoepidermal junction 664, 1501, 2118

Dermographism 94

symptomatic 707, 708

Dermo-hipodermal junction 755f

Dermoid cyst 190, 191f, 1481, 1491, 1492f

Dermopathy

diabetic 938

restrictive 346, 807

Dermoscopic melanoma-specific structures 1512

Dermoscopy 95, 1512f

score, total 98

Desanctis-cacchione syndrome 2004

Desmocollin 2 288

Desmoglein 577

cleavage of 84f

Desmoid fibromatosis 1526

Desmoid tumors, occurrence of 1586

Desmoplakin 285, 288, 577, 640f

Desmoplastic trichoepithelioma 1482, 1483, 1483f

Desmosomal disorders 207

Desmosomal proteins plakophilin-1 640f

Desmosomal skin pathology 288f

Desmosome 660f

cell-cell contacts 285f

inherited disorders of 284

Desquamated cells 10

Destruction plus congestive cardiac failure 1416

Deubiquitinase 839

Deuteromycetes 1869

Dexamethasone 2023, 2100

Diabetes mellitus 497, 499t, 937, 938t, 939, 940, 984, 1085, 1691, 2038

insulin dependent 937

noninsulin-dependent 939f

type 1 499, 937, 985

type 2 267, 333, 372, 984

Diacylglycerol 41, 846, 1096

Diaper area

care of 1976

eruption 622f

Diaper dermatitis 611, 612, 1850

distribution of 615f

severe chronic irritant 615

Diaper rash 611

Diapering methods, early 612

Diarrhea 926f, 2100

acute infectious 2100

Diascopy 95, 95f

Diazolidinyl urea 606

Didymosis 384

Diethylcarbamazine 1888

Diethyltoluamide 1718

Dietzia papillomatosis 1143

DiGeorge syndrome 436, 440

Digital constriction bands 262

Digital fibroma, infantile 1528

Digital herpes simplex 1284

Digital infantile fibromatosis 1529f

Dihydrorhodamine 434

Dihydrotestosterone 932, 1178, 1225, 1977

Dihydroxyindolecarboxylic acid 1095

Dihydroxyphenylglycol 887

Dimercaptosuccinic acid 1623

Dimethicone 1903

Dimethyl sulfoxide 1829

Dimethylaminopropylamine 606

Dimethylglyoxime-ammonia 603

Dimorphism-regulating kinase-1 1861

Dinitrochlorobenzene 1192, 1981

Diphenylcyclopropenone 1192, 1981

Diphtheria, cutaneous 1708, 1708f

Diprolene 1982

Direct bilirubin 1670

Direct fluorescent antibody 106

Direct immunofluorescence 674, 677, 786, 841, 1764

microscopy 88

technique 660

Direct microscopic examination 105

Direct smear fluorescent antibody test 1947

Dirofilaria immitis 1910

Discoid eczema 585f

Discoid lupus erythematosus 1203, 784, 1206, 1206f

lesions 785f

erythematous 785f

treatment of 2032

Discoid lupus lesions 786

Disease-modifying antirheumatic drugs 1866

Disialoganglioside 1573

Disseminated actinic superficial porokeratosis 245f

Distal interphalangeal finger joints 812

Distal onycholysis 493f

Distal psoriatic arthritis 826f

Distinct syndrome 790

Dithranol 1981

Dog bites 1662

Dogger bank itch 1618, 1619

Dominant dystrophic epidermolysis bullosa 640, 649, 2116

Donovanosis 1942

Dopamine beta-hydroxylase 887

Doppler ultrasonography 827

Dorfman-Chanarin syndrome 233f, 300

Dormancy 1416

Double lip 1308

Down syndrome 61, 142, 368, 369f, 920, 1040f, 1310, 1316, 1485f

Doxorubicin 2047

Doxycycline 1203, 1640, 2012

therapy 1275f

D-penicillamine 805, 886

Dracunculiasis 1893

Dracunculus medinensis 1893

Drosophila melanogaster 385

Drug hypersensitivity 110

syndrome 1668, 1669t

Drug interactions 2010, 2028t, 2036t

Drug rash 462, 563

Drug reactions 565, 1664

clinical manifestations of 1668t

cutaneous 462

diagnosis of 1676t

pharmacogenetics of 1666t

Drug therapy 679, 2023

Drulia uruguayensis 1617

Dry lusterless hair 918f

Dual-energy X-ray absorptiometry 2025

Ductal mammary ectasia 1495f

Dunnigan syndrome 1086

Duodenale 1889

Dupilumab 593, 2048

Duplication syndrome 55, 61

Dupré-Christol syndrome 1490

Dusky plaques 1710f

Dysbetalipoproteinemia, familial 882

Dyschromatosis 1145t, 1157

infection-related 1157

nutritional 1158

symmetrica hereditaria 1150, 1150f

types of 1157

universalis hereditaria 1151

Dyschromia 1150, 1153f

central 798f

Dyschromic amyloidosis cutis 1158

Dyshidrosis 626

Dyshidrotic eczema 585, 585f, 626, 627f

Dyskeratosis

congenita 323, 324, 338, 341, 343f, 1153, 1154f, 1332

hereditary benign intraepithelial 1327

Dyslipidemia 498, 937

Dysphagia 811

Dyspigmentation, postinflammatory 2067

Dysplasia

fibrous 61

hereditary mucoepithelial 1330, 1330f

low grade 1562

terminal osseous 386f

Dysplastic nevi 101f, 1511

Dysraphism 189f

skin manifestations of 190f

Dystrophic calcinosis cutis 1020, 1021

lesions of 1022f

Dystrophic epidermolysis bullosa 639, 640, 648, 649, 650f, 655, 1016, 2116

types of 649t, 650

Dystrophic nails 315f

Dystrophy 647f

congenital fascial 806, 807f

D-zone test 1690

Ear

infection 628f

lobe, non-cartilaginous 856f

pinnae hypertrichosis 1181

Ebola virus 743

Ecchymosis 75

Eccrine gland 22f, 25f

diseases of 1250

ducts 21f, 22f

Echinococcus 1892

granulosus 1892

Echinoderms 1617

Echoviral infection 1774f

Echovirus 1782

Econazole 1839, 1987

Ecotropic viral integration site 436

Ectasias, multiple 1396f

Ecthyma 1691

gangrenosum 474f, 1445f, 1725, 1725f

Ectodermal derivative impairment 323

Ectodermal dysplasias 5, 270, 285, 286f, 293, 300, 303–306, 313, 316, 321f, 322, 384, 640, 1157, 1166, 1167t, 1288

anonychia in 1273f

classification of 304t

Ectodermal mucosa 1556

Ectodysplasin 5, 304, 305

Ectonucleotide pyrophosphatase-phosphodiesterase 276, 1062

Ectrodactyly 305

ectodermal

defects 300

dysplasia 305, 316, 320

Eczema 573, 585f, 625

acute dyshidrotic 627f

area and severity index score 1985, 2049

asteatotic 632, 633f

chronic dyshidrotic 627f

coxsackium 579, 1774

craquelée 632, 633f

flexural 582f

follicular 585f

forms of 625

herpeticum 587f, 1785f, 1786

lichenified 439f

metabolic 630

mild but diffuse 581f

nummular 625

papular 1782

perinasal 581f

post-traumatic 629, 629f

psoriasis overlap 489

severe 581f, 583f

typical perioral 581f

Eczematous diseases 2028

Edaradd gene 304, 305

Edema 154, 812

acute hemorrhagic 751, 751f, 752f

blister 685, 685f

factor 1706

hereditary angioneurotic 960

vasogenic 1768

Edward syndrome 61, 370

Ehlers–Danlos syndrome 744, 1022, 1045, 1063t, 1065f

Ehrlichia 1716

chaffeensis 1716

ewingii 1716

Ehrlichiosis 1716

human monoyctic 1716

Eikenella corrodens 1662

Eipdermolysis bullosa 240

Elapidae 1659

Elastic fiber synthesis 1074

Elastic tissue nevus 1036f

Elastoma 1036f

Elastosis perforans serpiginosa 1015, 1017, 1017f, 1067, 1077

Elbow flexures 581f

Electra pilosa 1618

Electrocardiogram 1670, 1884, 2033, 2100

Electrocardiographic conduction defects 1128

Electrocardiography 362

Electroencephalography 155, 2100

Electrolysis 932

Electrolyte

disorders 2035

imbalance 300

Electromyogram 1670, 2100

Electromyography 813

Electron

energy loss spectroscopy 989

microscopy 91

Electrosurgery 1989

Elejalde syndrome 1102, 1103

Elementary body 1945

Embryonal tooth development 922f

Emery–Dreifuss muscular dystrophy 331

Emollients 605, 633, 1974

Emopamil binding protein 233

En coup de sabre 799, 1207

Enamel defects 360f

Encephaloceles 192, 1169, 1182

Encephalocraniocutaneous lipomatosis 184, 1168, 1538

Encephalopathy, hypoxic ischemic 156

Encephalotrigeminal angiomatosis 1391

Encoding anthrax toxin receptor 2 1527

Endemic typhus 1712

Endemicum 1119

Endocarditis 1727, 1939

Endocrine

abnormalities, multiple 942

cutaneous manifestations of 918

disorders 943, 2047

neoplasia, multiple 359, 913, 1034, 1333, 1519, 1546, 1588

Endocrinopathy 1251

Endoplasmic reticulum 39, 266

Endorphin 1096

Endothelial cells 1382f

epithelioid 1382f

Endothelin 1094, 1623

Endotracheal intubation 154

Energy

based devices 2072, 2072f

dispersive X-ray analysis 989, 990

fluence 2074

Engraftment syndrome 465

Entamoeba histolytica 1729

Enterobacter 1728

Enterobacteriaceae 1698

Enterobiasis 1893

Enterobius vermicularis 1304, 1893

Enterococcus faecalis 2097

Enteropathy 423, 445

Enteroviral exanthems 1774

Enterovirus 683, 1320, 1767, 1773, 1775t

infection 1773

Enzyme 837

cystathionine beta-synthase 735

defects 207, 208

dihydrofolate reductase 2017

immunoassay 1706, 1766, 1866, 1929, 1948

linked immunosorbent assay 166, 660, 674, 787, 967, 1711, 1721, 1857, 1889, 1948

replacement therapy 904, 2115, 2120, 2121t, 2122

Eosin stain 23f

Eosinophil 31, 36, 43, 85f

cationic protein 36

derived neurotoxin 36

rich dermatoses 770t

Eosinophilia 462, 563, 1007, 1008, 1378, 1668

myalgia syndrome 804, 805

Eosinophilic diseases 759, 770

Epicutaneous test 600

Epidemic typhus 1711

Epidermal acanthosis 80f

Epidermal appendages, development of 4

Epidermal dermal junctions 2116

Epidermal growth factor receptor 273, 1671

Epidermal hypermelanoses, primary circumscribed 1127

Epidermal nevus 273, 390, 393, 396, 397f, 404, 405, 2086f

epidermolytic 394f

group of 390

syndrome 390, 403, 404t

Epidermis 4f, 210f

cysts of 1479, 1488

embryonic 6f

keratinization of 9f

necrotic 725f

overall organization of 13f

papillomatous 218f

tumors of 1479

type lipoxygenase 3 225

Epidermodysplasia verruciformis 1553, 1577, 1803

Epidermolysis bullosa 80, 91, 144, 146, 185, 343, 374, 639–641, 643f, 892, 1152f, 1251, 1553f, 1908f, 2099, 2115

acquisita 661, 669, 669f, 670f

diagnosis of 655

hereditary 162

management of 653

nevi 646

pruriginosa 652, 653f

simplex 257, 639–643, 644f, 645, 1151

classification of 641t

pathophysiology of 644

superficialis 644

Epidermolytic ichthyosis 146, 147f, 203, 204, 215, 257

superficial 204, 211, 215, 218f

Epidermophyton 1823

floccosum 1836

Epidermotropism 1435

Epigenetic disorders 63

Epilepsy, myoclonic 374, 1539

Epiluminescence microscopy 95

Episodes, stroke-like 374

Epithelial cells 4, 1973

superficial 1285f

Epithelial membrane antigen 21, 1487, 1527

Epithelioma, sebaceous 316

Epithelium 2119f

Epsilon-aminocaproic acid 432

Epstein's pearls 149

Epstein–Barr virus 416, 449, 742, 997, 1010, 1325, 1444, 1461, 1571, 1670, 1722, 1762, 1777, 1778, 1989

infection 1776, 1777

Epulis, congenital 150

Eraser challenge 1635

Eratigena agrestis 1656

Erdheim–Chester disease 1439

Erosion 74, 150

Erosive perianal dermatitis 615, 616f

Eruption 75, 1674

cysts 150

exanthematous 1667

pustular 1671

urticarial 1669

Eruptive vellus hair cysts 1183, 1484, 1491, 1492f

Erysipelas 682, 1694, 1694f

Erysipeloid 1707, 1708f

leishmaniasis 1882

Erysipelothrix 1707

rhusiopathiae 1707

Erythema 75, 153, 218f, 310f, 585f, 691, 859f, 1434f

annular 691, 692

annulare centrifugum 691, 1833

type of 691f

chronicum migrans 691, 692, 692f, 693t

elevatum diutinum 960

induratum 1739, 1740

infectiosum 1761, 1768, 1769, 1769f

local 348f

marginatum 691, 693, 693f

migrans 1716, 1717

mild 1645f

multiforme 671, 683, 684, 786f, 717, 718f, 720f, 1606, 1642

classification of 717

lesions 1810f

neonatorum 123

nodosum 72f, 960, 1080f

leprosum 1081, 1751

perianal 1693f, 1703

perinatal 1703, 1703f

periocular 791f

periorbital 844

petechial 1771f

purpuric 725f

toxicum 134, 137f

neonatorum 134

widespread 1702f

Erythrasma 1709, 1709f

Erythrocyte sedimentation rate 529, 720, 739, 762, 788, 801, 822, 823, 835, 1010, 1598, 1810, 2043

Erythroderma 75, 218f, 223f, 290f, 448f, 563

causes of 563t, 564

diffuse 147f, 569f

evaluation of 569

management of 569

mild 568f

severe 839f

Erythrodermrittle hair, congenital 348f

Erythrodontia 891f

Erythrokeratoderma, progressive symmetric 221, 268

Erythrokeratodermia 295f

cardiomyopathy syndrome 290, 290f

variabilis et progressiva 269, 295

Erythromelalgia 696, 697f

Erythromycin 1203, 1231, 2015, 2041

Erythropoietic porphyria, congenital 890, 891f

Escherichia coli 103, 171, 1238, 1687, 1728, 1886

Esthetic products 2065

Estimated gestational age 3, 6f, 10

Estradiol 930

Estriol, unconjugated 65

Estrone 930

Estuary dermatitis 1618

Etanercept 514, 2043

Ethylenediaminetetraacetic acid 61

Eumycotic mycetoma 1857

European Academy of Allergy and Clinical Immunology 108

European American Lymphoma Classification 1459

European Competence Network on Mastocytosis 1453

European League Against Rheumatism 770, 812, 816t

European Medicine Agency 2049

European Pressure Ulcer Advisory Panel 1608, 1608t

European Standard Series of Contact Allergens 108t

Ewing's sarcoma 1573

Ewing's tumor, extraosseous 1573

Ex vivo gene therapy 2117

Exanthem 75, 1761

subitum 1771

classic childhood 1761

Exanthematous pustulosis, acute generalized 727, 1656, 1672, 1672

Excoriation 74

Exfoliants 1979

Exfoliative scales 74

Exogenous physiologic stratum corneum lipids, optimized ratio of 1975

Exophiala 1278

gougerotti 1859

Exophytic nevus 2068

Exostosis, subungual 1543, 1543f

Extensive chondrodysplasia punctata 235f

Extensive molluscum contagiosum 448f

infection 1806f

External genitals, atrophy of 796f

Extracellular lipid deposition 14f

Extracellular matrix 32, 344

protein 795, 909, 1075

Extracellular signal regulated kinase 36

Extracorporeal membrane oxygenation 154

Extragenital lichen sclerosus 1120f

Extragenital warts 1957

Exudative eczematous plaques 626f

Eye

anomalies 1348

infection, herpetic 1786

Eyebrows 348f, 364f, 1051f

dermoid cyst of 191f

loss of 338f

Eyelashes 338f

pediculosis of 1301

Eyelid

apocrine cysts, multiple yellowish 315

coloboma 406f

cysts 316f

multiple 315

infection, primary herpetic 1785f

lower 369f, 1369f

Eyeliner sign 396

Fab’ fragment antibody 828

Fabry disease 697, 903, 904f, 2122

Facial

afro-caribbean childhood eruption 1240

angiofibroma 358f, 2123f

aseptic granuloma, idiopathic 1239, 1240f, 1489

asymmetry 2068

dysmorphism 1181

edema 1238

erythema 465f, 693

hemiatrophy, progressive 799

hyperpigmentation, idiopathic 1138, 1138f

lentigines 1584f

papules 1780f

psoriasis 487, 489f

vitiligo 1111f

warts 439f

Familial chylomicronemia syndrome 881

Familial cold autoinflammatory syndrome 417, 709, 837

Fanconi anemia 62, 1552

Farber

disease 908

lipogranulomatosis 908

Farnesyl diphosphate synthase 244

Fas ligand activate cytotoxic T cells 1666

Fasciitis

eosinophilic 801, 804

intravascular 1528

necrotizing 1697, 1697f

nodular 1527, 1528f

Fat

metabolism 1086

necrosis, subcutaneous 86f, 156, 807, 1082, 1082f

Fatal disease 783

Fatty acids 210f

essential 2099

free 1225

very-long-chain 241, 1139

Fatty aldehyde dehydrogenase 211, 229

Fatty liver disease, nonalcoholic 499

Favus tinea 1828f

Feather hydroid 1615

Felon 1285

Femur 415f

Fermitin family homolog 269, 640, 657

Ferritin 1810

Ferrochelatase 892

Fetomaternal transfusion syndrome 744

Fever 926f, 1237f

acute rheumatic 693, 693f

enteric 1728

low-grade 1780

rat-bite 1727, 1732, 1732f

rheumatic 1727

spotted 1715

Fexofenadine 1975

Fibrillary myxoid stroma 1545f

Fibrinogen 1810

Fibroadipose vascular anomaly 1414

Fibroblast 36, 2089, 2117

growth factor 1025, 1357

receptor 390, 396, 403, 1243

Fibrodysplasia ossificans progressiva 1029, 1030, 1030f

Fibrofolliculoma 316, 1481, 1588

Fibroma 1533, 1861

hereditary 2041

periungual 360f

ungual 359

Fibromatosis

colli 1525

pseudosarcomatous 1527

superficial 1524

Fibrosarcoma 1567, 1569, 1570f

Fibrotic skin disease 806

Fibrous cephalic plaques 359f

Fibroxanthoma, atypical 1571

Fibulin 888, 1071

Fifth disease 1769f

Figurate erythema 691, 824f

Filaggrin

gene 15, 576

mutations 586f

Filariases 1887

Filoviruses 743

FILS syndrome 420

Fingertip, psoriasis of 493f

Fire ants 1649

Fissure 75

painful 796f

Fissured tongue 1309, 1309f

Fistula 75

Fitz–Hugh–Curtis syndrome 1936

Fixed drug eruption 683, 1140, 1666, 1673

Flaccid blister 84f

Flagellate dermatitis 1136, 1136f

Flaky paint dermatosis 1122f

Flat warts 1799, 1800f

Flaviviridae 1768

Fleas 1650

Flexural comedones 1487, 1488f

Flice-inhibitory protein 1961

Fluconazole 1842, 1854, 2020

Flucytosine 1854

Fluorescein isothiocyanate 1947

Fluorescence in situ hybridization 61, 213, 372, 449, 1505, 1562, 1723

Fluorescent treponemal antibody 788

absorption 166, 1119

Fluorine 2022

Fluorouracil compounds 1552, 1554

Flynn–Aird syndrome 333

Focal facial dermal

dysplasia 1182

hypoplasia 1055

Folinic acid 2031

Follicle center lymphoma, primary cutaneous 1467

Follicle-stimulating hormone 924

Follicular hyperkeratosis, prominent 212f

Follicular mucinosis, idiopathic 1473f

Folliculitis 1806

bacterial 1687

decalvans 1200, 1201, 1201f

gram-negative 1238, 1728, 2052

keloidalis 1039

nuchae 1039

Fonsecaea

compacta 1859

monophora 1859

nubica 1859

pedrosoi 1859

Food

allergy 576

assessment of 578t

interactions 2011

Foot

dermatitis 605f

dorsum of 256f

Fordyce spots 1309, 1309f

Forefoot eczema 585f

Foreign body 1302

granulomas 988, 989t

reaction 1481

Foreskin cyst 194f, 1494, 1494f

Forkhead box transcription factors 392

Formal eczema action plans 588

Forme fruste 1490

Formylglycine-generating enzyme 232

Fortuitum 991

Fossae, cutaneous 188

Fournier's gangrene 1697

FOXC2 gene 924

Fox-Fordyce disease 1256

Fragile X syndrome 60

Fragrances 604

Francisella tularensis 1731

Freckles 340f, 1127

Free testosterone 1199

Freund's leukemia integration site 1383

Frey syndrome 694

Friction blisters 686, 1612

Frictional lichenoid dermatitis 1611, 1611f

Frostbite 1266, 1597

Frostnip 1597

Fumarate hidratase 1571

Fumaric acid esters 512

Fungal

cultures 105

dermatitis, invasive 1851

hyphae 105f

infections 1285, 1822

neonatal infections 171

Furuncles 1687

Furunculosis 1806

Fusarium 472, 1838, 1987

sepsis, necrotic nodule of 1855f

Fusidium coccineum 1986

Fusion inhibitors 462

Fusobacteria 1323

Fusospirochetal gingivitis 1322

Futcher's line 1131f

G protein signal transduction, disorders of 941

Galactosialidosis 1446

Gallop rhythm 864

Gamasidae 1913

Gamete formation 59f

Gamma

aminobutyric acid 1902

carboxyglutamate 1062

delta T-cell lymphoma

cutaneous 1467

primary cutaneous 1467f

globulin 2037

secretase protein complex 764

Ganglioneuroma 1546

Gangliosidosis 905

Gangrene 75, 1694

Gardner fibroma 1526, 1587

Gardner syndrome 961, 1582, 1586, 1586f

Gardner–Diamond syndrome 744

pathogenesis of 744

Gardnerella vaginalis 528, 1723

Gastrointestinal disease 500, 956

Gastropoda 1617

GATA2 deficiency 1085

Gaucher disease 904, 2120, 2121

Gel electrocardiogram 155

Gene 56

carriers 58

conversion 2120

disorders, single 55, 65

gun 2116

mutation

database 63

single 57

serping 712

simplified structure of 56f

testing 62

therapy 55, 2115

approach 2117fc

Genetic 486, 1099, 1505

disease 5, 56f, 807, 1291, 2123

oral manifestations of 1327

disorders 59, 923t, 1098, 2116, 2123

dyschromatoses 1150, 1153

information, packaging of 55

mutations 60

nail disorders 1286

skin disorders 2115

syndromes 1050t

testing 63

tumor prone syndromes 1577, 1577t

Genital herpes simplex 1305

virus infections 1958, 1958f

Genital mucous membranes, disorders of 1303

Genital region, primary herpetic infection of 1786

Genital ulcer 857, 968

acute 1305

disorder 1942

Genital warts 1953f

external 1953, 1955

Genitalia

abnormal 1128

anatomy of 1304f

Genodermatosis 1166, 2120t

Genomic hybridization 1505, 1562

Geographic tongue 1315, 1316f

Germ tube formation 106f

Germinative cells 1261

Germline

GJB2 disorder 297

rasopathies 351, 361

Gerodermia osteodysplastica 1073, 1074

Gianotti–Crosti

lesions 1774

syndrome 72f, 461, 461f, 1780f, 1782

Giant cell

fibroblastoma 1567

multinucleated 37, 996f

tumor 1533

Giant collagenoma 1036f

Giant congenital melanocytic nevus 2112f

Gingival fibromatosis 1525

hereditary 1525

idiopathic 1525

Gingival overgrowth, drug-induced 1525

Gingivitis 1025f

acute necrotizing ulcerative 1322

desquamative 1317

Gingivostomatitis 1320

herpetic 1321, 1321f, 1785f

Glands 21

eccrine 22f, 25f

Glassy membrane 20f

Glaxosmithkline 1986

Globular halo nevus, involution of 1511f

Glomangioma 1412

Glomerular filtration rate 1670, 2035

Glomerulonephritis 1694

postinfectious 650

Glomuvenous malformation 1351, 1364, 1387, 1412, 1413f

Glossitis 889, 1316, 1785f

idiopathic 1317f

Glucocorticoids 474, 848, 881, 925, 1811, 2023–2025

potencies of 928f

stress doses of 926t

systemic 2022

therapy 2023, 2024

Glucocorticosteroids 2022

Glucose

6-phosphate dehydrogenase 666, 2017, 2034, 2036

tolerance tests 937

transporter 1357, 1362, 1373

Glucosylceramide 227

Glutamic oxaloacetic transaminase 1026

Glutamic pyruvic transaminase 1026

Glutaric acidemia 875, 876

Glutaryl-CoA dehydrogenase 875

Glutathione-S-transferase 2027

Gluten-free diet 674, 679

Gluten-sensitive enteropathy 678

Glyceryl trinitrate 696

Glycogen synthase kinase-3 392

Glycolic acid 227, 1974

Glycosaminoglycans 32, 905, 2122

Glycosylation, congenital disorders of 888, 1074

Glycyrrhiza glabra, root of 2098

Gnathostoma 1888

spinigerum 1888

Gnathostomiasis 1888

Gobello syndrome 404, 406, 406f

Goeckerman therapy 510f

Goeminne syndrome 1037

Göhlich–Ratmann syndrome 1526

Goldenhar syndrome 1543

Golf tee hair appearance 1177f

Golgi apparatus 887

Goltz syndrome 313, 314f, 1319

Gomez–Lopez–Hernandez syndrome 1167

Gonadal dysgenesis 922, 924f, 924t

Gonadal mosaicism 355

Gonadotropin-releasing hormone 932

Gonionemus vertens 1616

Gonococcal infection 1939, 1940, 1949

disseminated 1936, 1937f, 1939, 1940

uncomplicated 1938

Gonorrhea 1937

Gonyaulax breve 1619

Goodpasture's syndrome 966

Gorlin's syndrome 275, 1489, 1554f, 1580f, 2004

Gottron's papules 811

Graft-versus-host disease 437, 465, 467f, 469f, 566, 775, 801, 1255, 1329f, 1606, 2119

vitiligoid chronic 470f

Gram-negative bacteria 1718, 1719t, 1723, 1985

Gram-positive bacteria 1703, 1704t

Granular cell 18

tumor 1546

Granular keratinocytes, acantholysis of 84f

Granular parakeratosis 552, 553f

Granulocyte 50f

colony-stimulating factor 464, 759, 1325, 1606

Granuloma 843

allergic foreign body 989

annulare 938, 939, 983, 984, 987f, 988, 1016, 1081

classic 83f

disseminated 2033

management of 988t

papular umbilicated 986f

subcutaneous 986f, 1081

cutaneous noninfectious 449f

gluteale infantum 620, 620f, 1850

inguinale 1918, 1942, 1943t

necrotizing palisading 966

nonallergic foreign body 989

umbilical 152, 152f, 194

Granulomatosis 753, 956, 965–967, 1328

diagnosis of 967t

eosinophilic 754

lymphomatoid 997

Granulomatous disease, chronic 432, 433, 433t

Granulosis rubra nasi 1255

Graves’ disease 920–922, 1056

Gray patch tinea 1827, 1828f

Green nail syndrome 1724

Greither's palmoplantar keratoderma 262f

Griffiths’ classification 550t

Griscelli syndrome 425t, 848, 1098, 1100, 1102, 1103f, 1155, 1156f, 1445

Griseofulvin 2018

therapy, potential adverse effects of 2019t

Growth hormone 922

deficiency 922

disorders 922

excess 922

primary 922

Guanine 56

Guanosine triphosphate 433, 1026

Guillain–Barré syndrome 1708, 1791

Gunther disease 336, 341, 890

Gustatory erythema 694

Guttate psoriasis 491, 491f, 502, 503f

Gyrate erythemas 691

H syndrome 374, 843, 1139, 1139f, 1182

H1 antihistamines 1455

Haemophilus ducreyi 1941

Haemophilus influenzae 164, 429, 438, 460, 1696, 1727, 2016

infection 164

type B 990, 1695

Hailey–Hailey disease 243

Haim–Munk syndrome 268

Hair 1163

acquired progressive kinking of 1177

camouflage techniques 2069

counts 113

cutting 1638

cycle changes 127

disease 113, 114t

disorders 1165

feathering 113

findings 533

follicle 8f, 20, 20f, 21f, 25f, 677f, 1436f, 2074f

bulb of 20f

light of 20f

nevus 399, 402

growth window 113

integration systems 2070

invasion 1826t

loss

classification of 1185

disorders, acquired 1185, 1200

morphology 10f

multiple 1481f

patterns 127

pull test 113

removal 2087t

shaft 10, 114, 114f, 1899f

abnormalities 1170

thinning 929f

transverse sections of 20f

typical thinning 929f

uncombable 1174, 1175f

Hairpieces 2070

Hairy cutaneous malformations 1180

Half-and-half nails 1277f

Half-buried horizontal mattress sutures 2108

Hallermann–Streiff syndrome 335, 1169

Hallopeau acrodermatitis continua 494

Hallux nail 1280f

Halo nevi 1510

Haloclava producta 1619

Halt disease 2122

Hamamelis virginiana 2099

Hamartoma

eccrine angiomatous 402, 1183, 1484

fibrous 1527, 1531, 1532f

meningothelial 1544

neuromuscular 1544, 1545f

precalcaneal fibrolipomatous 1524f

syndrome 404, 1422

multiple 1587

Hand

atopic dermatitis 583f

dorsum of 720f

eczema 583f

Hand-foot

mouth

buttock syndrome 622

disease 683, 683f, 1265, 1320, 1773, 1774f

skin reaction 698

Hansen's disease 1746, 1750

Hantavirus 743

Hapalochlaena 1617

Hapalonychia 1269f

Happle–Tinschert syndrome 1484

Harlequin ichthyosis 221, 227, 228f

Hartnup disease 875

Hartnup disorder 877

Hashimoto's thyroiditis 920

Hashimoto–Pritzker disease 142, 745

Hay–Wells syndrome 219, 316, 1291

Head lice 1903

family of 1898f

Hearing loss 843

Heart

anomalies 843

disease, congenital 739

failure, congestive 919, 2045

monitoring, fetal 153

Heat urticaria 710

Helicobacter pylori 739

Heliotrope eruption 811

Helminthic

diseases 1887, 1891

infections 775, 1880

Helminths 476

Hemangioendothelioma 1381, 1381f

epithelioid 1383

pseudomyogenic 1381

Hemangioma 1347, 1348, 1363

congenital 1348, 1363, 1373, 1374, 1375f, 1376, 2122

epithelioid 1007, 1373, 1378

gepatic 1363

infantile 1348, 1357, 1358, 1360, 1362f, 1364, 1366, 1369, 1373, 1530, 2080, 2081t

lobular capillary 1378

multifocal infantile 1363

multiple infantile 745

noninvoluting congenital 1348, 1349, 1349f, 1373, 1375

periocular infantile 1363

segmental infantile 1349f

ulcerated infantile 2081f

verrucous 1355, 1413, 1413f

Hematologic diseases 695

Hematoma 75

subungual 1275f

vulvar 1613

Hematopoietic stem cell transplantation 313, 323, 463, 907, 1471, 2120

Hematopoietic system, diseases of 1429

Hematoxylin 23f, 1417f

Hemidysplasia, congenital 380, 386, 395, 395f, 403

Hemihypertrophy 1182, 1355f

Hemivertebrae 406

Hemochromatosis 940, 964

hereditary 964

Hemoglobin 2075

Hemolytic disease 145

Hemophagocytic lymphohistiocytosis 824, 848, 1083, 1444, 1445f

Hemophagocytic syndrome 1466

Hemophagocytosis 1435

Hemophilia

A 737

B 737

Hemorrhage 1352f

splinter 1275f

subconjunctival 153

subungual 1276t

Hemorrhagic disease 738

Hendersonula toruloidea 1838

Henoch–Schönlein purpura 417, 575, 686, 686f, 749, 749f–751f, 1727

Heparan sulfate proteoglycan 6

Heparin, low-molecular-weight 740

Hepatic disease 739

Hepatic disorders 2039

Hepatitis

reactivation 2048

virus 1057, 2038

C virus 461, 1325, 2038

Hepatocyte growth factor 1094

Hepatorenal syndrome 2017

Hepatosplenomegaly 417, 443, 447, 824, 843

Hepatotoxicity 2045

Heredopathia atactica polyneuritiformis 230

Hermansky–Pudlak syndrome 848, 1098, 1099, 1101

Hernia

inguinal 888

umbilical 918f

Herpangina 1320, 1774

Herpes genitalis

first episode of 1959t

recurrent 1960

Herpes gestationis 946, 947

neonatal 146

Herpes labialis 1786, 1989

Herpes simplex 162, 648, 682

infection 1302, 1783

virus 107f, 144, 166, 239, 460, 473f, 579, 718, 1302, 1690, 1771, 1785f, 1942, 1989, 2009, 2010

disease, recurrent episodes of 1960

infections, treatment of 1788t

Herpes zoster 683, 1303, 1792

infection 1793f

ulcerating 461f

Herpesviridae 1783

Herpetic whitlow 1284, 1785f, 1786

Herpetiform ulcers 1317

Herringbone 1265

Heteroplasia, progressive osseous 942, 1026, 1027, 1028f

Hexachlorophene 1972

Hexylene glycol urea 1982

Hibernoma 1540

Hidradenitis

eccrine 1610

suppurativa 764, 840, 1237, 1488, 1857, 2042

Hidrocystoma 1493, 1493f

eccrine 81f

Hidrotic ectodermal dysplasia 322, 323f

Highly active antiretroviral therapy 936, 1824

High-voltage accidental electrical injuries 1604

Higoumenaki's sign 1928

Hirschsprung's disease 956, 960, 961f

Hirsutism 932, 1208

Histiocytic pseudorosettes 1010

Histiocytoma

angiomatoid fibrous 1569

malignant fibrous 1569, 1572

Histiocytosis 1006

benign cephalic 1441, 1442f

congenital 162

Histogenesis 121, 1099

pathology 1930

Histoplasma 106, 1867

capsulatum 1866, 2020

Histoplasmosis 1866, 1867, 1871

acute disseminated 1867

cutaneous 1867

primary 1867

secondary 1867

Hobo spiders 1656

Hodgkin's disease 1204, 1464, 1472

Hodgkin's lymphoma 974, 1272, 1546

Hodgkin's syndrome 316

Holocarboxylase synthetase 888

Holothuroidea 1617

Homeopathy 2101

Homocysteine 873

total 873

Homocystinuria 735, 873

Hormodendrum pedrosoi 1859

Hormonal therapy 1234

Hormone

adrenocorticotropic 922, 1096, 1128, 1671, 2025

lipotropic 1096

luteinizing 930, 1199

sensitive lipase 1086

Hortaea werneckii 1855

Host defense proteins 31, 33

Hot tub folliculitis 1620

Howel–Evans syndrome 272

Hoyeraal–Hreidarsson syndrome 344

Human chorionic gonadotropin 948

Human embryonic skin, transmission electron micrograph of 6

Human herpesvirus 530, 1007, 1381, 1444, 1446, 1668, 1762, 1772

Human immunodeficiency virus 140, 171, 423, 458, 460f, 461f, 505, 511, 526, 724, 739, 770, 983, 984, 1004, 1010, 1057, 1233, 1278, 1469, 1571, 1579, 1687, 1765, 1918, 2009

infection 1923, 1937, 1950, 1960

Human leukocyte antigen 19, 244, 528, 674, 718, 724, 783, 796, 817, 820, 822t, 941, 1190, 1319, 1643, 1666

Human papillomavirus 237, 275, 461, 530, 990, 1197, 1319, 1577, 1796, 1953, 1954, 1989

vaccination 1956

Hunter syndrome 907, 1034, 2116, 2121

Huriez syndrome 266

Hurler–Scheie, Scheie syndrome 2121

Hutchinson's teeth 1927, 1928f

Hutchinson–Gilford progeria syndrome 329, 330f, 331f, 1016, 1034, 1087, 1168

Hyaline fibromatosis

juvenile 1525, 1526

syndrome 910, 910f, 1526, 1527f

Hyaline material, deposits of 1527f

Hyalinosis

cutis et mucosae 1332

infantile systemic 1526

Hydration 2038

Hydroa vacciniforme 685, 686, 892, 1465, 1644, 1644f, 1998

Hydrocortisone 2022, 2023, 2100

acetate 606

powder 1972

Hydrous magnesium silicate 1976

Hydroxy vitamin D 591

Hydroxylase deficiency 931

Hydroxypregnenolone 931

Hyperandrogenism 937

Hypercholesterolemia 879, 880f

familial 878, 882

Hyperchromatic nuclei 1530

Hypercoagulable states 733

Hyperemia, cutaneous 1183

Hypereosinophilic syndrome 770, 774

Hyperglobulinemic purpura 743

Hyperhidrosis 1250, 1251f

profuse 1251f

Hyperimmunoglobulin

D syndrome 836f

E syndrome 140, 437, 439f, 772, 1324

M syndrome 444, 444f

Hyperimmunoglobulinemia D 417, 836

Hyperkeratinization, follicular 1225

Hyperkeratosis 218f, 318f, 585f, 1798

epidermal 146

epidermolytic 215

massive 218f

mild 218f

periungual 271

severe 218f, 256f

subungual 493

Hyperkeratotic follicular papules 1241f

Hyperlipidemia 497

familial combined 878, 881

mixed 882

Hyperlipoproteinemia 878, 881, 882

Hypermelanoses, nonblaschkoid segmental 1132

Hyperorthokeratosis 533f

Hyperphenylalaninemia 871

Hyperpigmentation 310f, 1133f, 1136f, 1145t, 1151

chemotherapy-induced 1141t

cutaneous 2069t

disorders 1127

familial progressive 1142, 1151

miscellaneous disorders of 1142

mucocutaneous 1585

multiple small 71f

peripheral 798f

postinflammatory 79f, 1129, 1136

progressive 1142

stage 309

Hyperplasia

congenital adrenal 926, 931

epidermal 1016f

focal epithelial 1319

sebaceous 1487, 1487f

Hypersensitivity

syndrome 2029, 2036

vasculitis 1727

Hypertelorism, ocular 1128

Hypertension 497, 498, 937, 2038

intracranial 2054

Hyperthyroidism 920

Hypertrichosis 895f, 1177–1179, 1179t, 1182, 1183

Cantu syndrome consists of 1177

cubiti 1181f

diffuse 1177

drug-induced 1178, 1180f

lanuginosa 1177

localized 1180, 1182

prepubertal 1178

primary 1177

secondary 1178

X-linked

dominant 1178

recessive 1178

Hypertrichotic plaques 843

Hypertriglyceridemia 878, 882, 2054

Hypertrophic scars 1035, 1038f, 1791f, 2068

management of 2111f

Hypertrophy 75, 2068, 2079f

Hyperviscosity syndrome 695

Hypoadrenalism, causes of 926t

Hypoalbuminemia 1810

Hypocomplementemia 513

Hypocomplementemic urticarial vasculitis syndrome 753

Hypodontia 306

nonsyndromic 303

Hypoglycemia 122, 685

Hypoglycemics, oral 2020

Hypogonadism 843

Hypogranulosis 502f

Hypohidrosis 300, 305

Hypohidrotic ectodermal dysplasia 304, 305, 306f, 307, 307f, 312

classic 305

diagnosis of 306f

Hypomelanosis 1117

drug-induced 1116

infectious 1118

progressive 1117

Hyponychia congenita 1291

Hyponychium 21

tumors of 1264f

Hypopigmentation

acquired 1116

disorders of 1109

diffuse 1100

disorders of 1098

familial progressive 1151

localized 1185

perifollicular 100f

streaks 310f

transient 607f

Hypoplastic hyperconvex toenails 924f

Hypotension 1660

Hypothermia 122

Hypothyroidism 882

acquired 919f

congenital 918, 918f, 1310

Hypotrichosis 291–293, 305, 1165–1169

congenital 1166, 1166f

localized autosomal recessive 292

severe neonatal 1167t

simplex 291

Hypoxanthine guanine phosphoribosyl transferase 2027

Hypoxia inducible factor 1357, 2051

Ichthyoses 203, 210f, 1974

nonsyndromic 204, 211

syndromic 204, 229

Ichthyosiform

disorders 1981

erythroderma 2122

bullous congenital 146

classical congenital 222f

congenital 204, 211, 219, 225, 1167

nonbullous congenital 225

lesions, segmental 235f

nevus 380, 386, 395, 403

scales 74

Ichthyosis 204, 210, 216, 220, 232, 240, 241, 264, 270, 299, 300, 329, 348, 1167, 1168, 1979

acquisita 973, 974

congenita 269, 1043

follicularis 240f, 1167

alopecia, and photophobia syndrome 266

foundation for 225

hands 212f

hyperproliferative 209

phenotypes 15

prematurity syndrome 241

types of 210f

vulgaris 211, 212f

typical histology of 212

X-linked recessive 203, 212f

Id reaction 628

Idiopathic skeletal hyperostosis, diffuse 2053

Imidazoles 1987, 1988

Imiquimod 1552, 1957

Immersion foot 1598

Immune

complex

disease 754

small vessel vasculitis 749

deficiency syndrome 312, 1688

dysregulation 144, 423, 426t, 445, 846, 847

mediated disorders 33

reconstitution inflammatory syndrome 458

surveillance 45

thrombocytopenic purpura 739

Immunity

cell-mediated 1750

cutaneous 31

herd 1761

Immunization 1792

Immunobullous diseases 2028

Immunochromatographic test 1888

Immunodeficiency 307, 413, 440, 1291, 568, 2043

disease, primary 415, 416, 2123

disorders

primary 415t, 418t

treatment of 2122

iatrogenic 1579

severe 449f

syndromes 1168

Immunodysregulation polyendocrinopathy enteropathy X-linked syndrome syndrome 440

Immunoelectrophoresis 1859

Immunoflourescence 88, 787, 947

assay 1710

Immunoglobulin 47, 416, 438, 443, 749, 1009, 2037

A 48, 80, 336, 420, 500, 674, 1266, 1277

deficiency 440

D 48, 837

deficiency disorders, primary 441t

E 36, 48, 226, 239, 290, 703, 1664, 1689, 1846, 2046

G 37, 48, 91, 146, 661, 785, 947, 1664

M 47, 48, 336, 533, 821, 822, 1057, 1930

vasculitis 749

Immunohistochemistry 87, 1376

Immunopathology 413

Immunoreactive trypsinogen 966

Immunoregulatory T-cells 18

Immunosuppressants 2022

Immunosuppression

acquired 458

iatrogenic 473

systemic 500

Immunosuppressive

agents 474

drugs 2022

T cells 40

therapy 1113

Immunotherapy 591

Impetigo 1684

bullous 84f, 682, 1685f

herpetiformis 948

neonatorum 162

nonbullous 162f, 1684f

In vitro fertilization 65

In vivo technology 2117

Inadequate corticosteroid therapy 812

Incontinentia pigmenti 59, 84f, 143, 143f, 308, 310f, 311, 311f, 1101, 1145, 1291

features of 311

neurologic features of 311

skin features of 309

Index finger, congenital onychodysplasia of 1290, 1290f

Indirect hemagglutination assay 1736

Indirect immunofluorescence 660, 674

microscopy 90

Indomethacin 2100

Infantile hemangioma 1348, 1357, 1358, 1360, 1362f, 1364, 1366, 1369, 1373, 1530, 2080, 2081t

anatomic location of 1360t

differential diagnosis of 1361t

management of 1366

risk stratification of 1367t

superficial 1349f

Infections 621, 939, 1363, 1807

aquatic 1619

bacterial 162, 682, 893f, 1683

catheter-associated 1845

cutaneous 459

enteroviral 1727

herpetic 1786

mycobacterial 1621

neonatal 1949

perinatal 1961

protozoal 1880

recurrent 419t

secondary bacterial 581f

Infectious diseases 45, 102, 162, 566, 2072

Inflammation 1225

laboratory evidence of 1810

Inflammatory airway diseases, chronic inducible 44

Inflammatory bowel disease 500, 764, 826, 827, 956, 1081, 1104, 2013, 2042, 2054

Inflammatory diseases 564, 1313, 2042, 2072

pathogenesis of 2049

treatment of 2025

Inflammatory disorders 33

Inflammatory linear verrucous epidermal nevus 394, 395f, 535, 536, 536f

Inflammatory skin disease, treatment of 2022

Infliximab 515, 2042

Influenzae infection 1728f

Infraorbital dennie 579

Ingrown nails 1279

Injury

aquatic 1614

extravasation 155

neonatal 153

nonaccidental 736

physical 1635

postnatal 154

prenatal 153

severe 926t

Innate lymphoid cell 36

Inner luminal cells 23f

Inner root sheath system 20f

Inosine monophosphate dehydrogenase 2031

Inositol trisphosphate 846, 858

Insect 1649

bite 683, 683f, 1650f

reaction 1650f

Insulin 939

like growth factor 922, 1225, 1357

resistance 882, 937t

disorders of 933

syndromes 934

Intellectual disability 1041

Intense erythema 1434f

Intense pulsed light 2074, 2081, 2089

Intensive care unit 1608, 1811

Intercellular adhesion molecule 210, 445, 1202, 1980, 2043

Intercellular desmosomes 80f

Interdigitale 1286

Interferon 32, 436, 983, 2039

alpha 784, 1379

gamma 210, 530, 718, 1010, 1025, 1225, 1324, 1445, 1666, 1980, 2022

genes, stimulator of 840, 841

Interfollicular keratinization 4f

Interleukin 19, 32, 43, 210, 290, 438, 530, 630, 817, 820, 835, 858, 958, 983, 1007, 1190, 1225, 1324, 1810

receptor antagonist, deficiency of 486, 838f, 839

Interphalangeal joint 275f, 1025f

proximal 1599

Interstitial granulomatous

dermatitis 825, 827

drug reaction 827

Intracellular cobalamin transport 1142

Intracytoplasmic sperm injection 65

Intradermal skin test 110

Intraepidermal neutrophils, spongiform pustular’ distribution of 502f

Intrauterine

device 1227, 1850

epidermal necrosis 148

growth restriction 1771

herpes simplex virus infection 167f

Intravascular coagulation

disseminated 733, 739, 1656

localized 1396

Intravenous amphotericin B 1987

Intravenous immunoglobulin 290, 313, 663, 711, 723, 818, 848, 967, 1446, 1771, 1811, 2037, 2038

off-label dermatologic uses of 2037t

Inversa recessive dystrophic epidermolysis bullosa 650

Involucrin 257

Iodine 2040

Iris 314

Irritant diaper dermatitis 611, 613, 614, 615f

clinical features of 614

differential diagnosis of 616

epidemiology of 614

management of 617

pathogenesis of 617

prevention of 618

severe 615f

treatment of 618

Isohemagglutinin 313

Isothermal amplification, loop-mediated 1796

Isothiazolinone 2066

Isotretinoin 1234, 2051

Itch

scratch cycle 1975

types of 2066f

Itchy papules 627f

Ito hypomelanosis 1101

Ito nevus 1134, 1135f

Itraconazole 1640, 1842, 1854, 2019, 2041

Ivermectin 1902, 1910

Ixodes 1652

Jacquet's diaper dermatitis 615, 616f

Jadassohn sebaceous nevus 1169

Janus kinase inhibitors 593, 2049

Jaundice, physiologic 125

Jaw cysts 1581

Jellyfish tentacles 684f

Jessner's lymphocytic infiltration 785, 1006

Jewels, cluster of 666

Job syndrome 140

Jogger's nipples 1614

Joint laxity 888

Junctional epidermolysis bullosa 7, 639, 640, 645, 646, 647f, 2117

pathophysiology of 647

subtypes of 646t

Juvenile idiopathic arthritis 693, 788, 818, 820, 822t, 968, 1673

characteristics of 823t

clinical syndromes of 822

heterogeneity of 820

treatment of 827

Juvenile idiopathic inflammatory

myopathies 816t

myositis 817

Juvenile systemic sclerosis 801, 802, 803f

diagnosis of 803t

Kala-azar 1871

Kaposi's sarcoma 462, 974, 1381, 1723, 2041

AIDS-associated 2039

Kaposiform hemangioendothelioma 741, 1349, 1350, 1350f, 1376, 1378, 1379f, 1380f

Kasabach–Merritt phenomenon 732, 741, 1349, 1376, 1379, 2039

Katayama syndrome 1892

Kawasaki's disease 530, 611, 749, 858, 859f–862f, 1271, 1446

incomplete 862

treatments 1811

Kawasaki's syndrome 2037

Kayser–Fleischer rings 885

Kearns–Sayre syndrome 374

Keloid 1035, 1038f, 1520, 1857, 1861

scar 1520f

spontaneous 1037

treatment of 1039t

Keratin filaments 8f, 209

Keratinization

disorders of 2051, 2052

follicular 4f

Keratinocyte 18f, 35, 49, 49f, 210f, 286f, 2048, 2117

apoptosis 536f

cells, mature 17

Keratinocytic nevus 390, 396

epidermolytic 394

linear 392

nonsegmental 396, 396t

syndromes 404

Keratinopathic ichthyoses 204, 215, 218f

Keratitis 857, 1167, 1785f

ichthyosis-deafness syndrome 204, 267, 269, 270f, 294, 294f, 297, 567

interstitial 1928

Keratoconjunctivitis 889

Keratoderma 270, 348

aquagenic 1621

blennorrhagica 529f

focal palmoplantar 270, 271

hypotrichosis-leukonychia totalis syndrome 270, 298, 298f

mutilating 264

perianal 267

sclerosing 269, 1043

Keratohyalin granules 17

Keratolysis

exfoliativa 632, 633f

pitted 1709, 1710f

Keratosis 75, 241

follicular 212f, 214

follicularis 241

spinulosa decalvans 240, 1051, 1200

lichenoides chronica 538, 538f

linearis 269, 1043

palmoplantaris varians 271

pilaris 586, 586f

atrophicans 1050, 1051f, 1173, 1200, 1201t

decalvans 1051

Ketoacidosis, diabetic 685

Ketoconazole 1987, 2019

shampoo 1847

Kidney

disease 2021

chronic inducible 2030

injury, acute 1811

Kikuchi's disease 1010, 1011f

Kikuchi's syndrome 1290

Kikuchi–Fujimoto disease 1010

Kimura's disease 1007, 1008t

Kinase deficiency 440

Kindler syndrome 344, 344f, 345, 639, 639f, 656, 656f

Kinky hair syndrome 1171

Klebsiella 1687, 1728

granulomatis 1943

pneumoniae 1694

Klein–Waardenburg syndrome 1105

Klinefelter syndrome 60, 309, 372, 1243

Klippel–Trenaunay syndrome 1355f, 1395, 1396f

Knee, geographic patch on 1396f

Knot tying 2107

Knuckle

pads 256, 1525f

sign 371

Kobberling syndrome 1086

Köbner phenomenon 78, 78f, 1806f

Koenen tumors 359, 360f

Koilonychia 1270f

Koplik's spots 1763, 1763f

KRT9 gene 219

Kwashiorkor 949, 950f, 1121, 1122f

dermatosis of 1122

Kyphoscoliosis syndrome 335, 1180

Kyphosis 335, 406

Kyrleśs disease 1015, 1016, 1018

Kytococcus sedentarius 1709

Labial telangiectasias 969f

Lacerations 154, 1628

intrapartum 154

Lacrimal gland dysfunction 300

Lactate dehydrogenase 588, 736, 1026

Lactic acid 227, 1974

dehydrogenase 1810

Lactic acidosis 374

Lactic dehydrogenase 815

Lamellar ichthyosis 204, 211, 212f, 219, 1167, 2115

phenotype 222

classical 222f

Lamina densa 23, 639f

Lamina lucida 6, 23, 639f

Langerhans cell 3, 10, 18, 19, 19f, 37, 49, 49f, 50, 718, 1431, 1438, 1975

histiocytosis 142, 1328, 1431, 1432, 1438, 1329f, 1434f, 1435f

congenital 142, 143f

cutaneous manifestations of 1431

Lanolin 605

Laron syndrome 922

Larva migrans 1889, 1890f

cutaneous 1889

Laryngo-onycho-cutaneous syndrome 646, 647

Laser

ablation 969

cooling systems 2075

hair removal 2087

light, properties of 2073f

medium 2073

modalities 1370, 2088

settings 2074

system, elements of 2073f

tattoo removal 2085

therapy 932, 2072, 2073, 2075

indications for 2077

Last cuticle sign 94

Laterothoracic exanthema, unilateral 1777, 1781, 1782f

Latrodectus genus 1654

Latrodectus mactans 1654

Laugier–Hunziker syndrome 1584, 2085, 2085f

Laurence–Moon–Biedl syndrome 1274

Lavandula officinalis 2098

Lawrence syndrome 1086

L-dihydroxyphenylalanine 1099

Lebrikizumab 594

Lebrunia danae 1619

Lectin pathway 32

Led therapy 2089

Leg herniations 1613

Legius syndrome 352, 361, 374, 1129

Leiomyomatosis, hereditary 1541

Leiomyosarcoma 974, 1567, 1571

Leishmania 104, 1880, 1881, 1885

donovani 1118

major 2020

recidivans 1881, 1882

Leishmaniasis 1883f, 2005

atypical cutaneous 1882, 1882t

clinical forms of 1881t

cutaneous 87f, 1880, 1885t

diffuse cutaneous 1880, 1881, 1883

disseminated 1883

eczematous 1882

localized cutaneous 1880, 1881

mucocutaneous 1881, 1883

neonatal 1882, 1883f

pediatric cutaneous 1882

verrucous 1882

cutaneous 1883f

Lentiginoses 1128

Lentigo simplex 1128

Lentivirus 2117

Lenz microphthalmia syndrome 1543

Leopard syndrome 362, 363f, 1128, 1546

Leprechaunism 934

Lepromatous disease 1748, 1750

Lepromatous leprosy 1118, 1749, 1749f, 1861

Leprosy 1119, 1746

classification of 1748f

indeterminate 1119f, 1748, 1748f

presentation of 1749

Leptospira interrogans 1736

Leptospirosis 1736

Lesch–Nyhan syndrome 1282

Lesions

cutaneous 189t, 725

eczematous 585f

herpetic 1786

inflammatory 1236f

linear arrangement of 298f

multiple hypopigmented 1108f

necrotic 750f

nodular 1859

papular 1166

psoriatic 78f

ulcerated 1745f

urticarial 705f

Lethal factor 1706

Leucovorin 2031

Leukemia 470f, 895f, 1329f, 1459, 1470

acute 1471, 1912f

lymphoblastic 882, 1471

lymphoid 1471f

megakaryoblastic 370

myeloid 370, 436, 1130, 1470, 1471

myelomonocytic 1471

chemotherapy for 473f

congenital 1471

cutis 1459, 1470

congenital 1472f

juvenile myelomonocytic 352, 1470

mixed lineage 1471

neonatal 1471

Leukemoid reactions 1471

Leukocyte 36

adhesion deficiency 46, 445, 445f

function 46

migration 2044

vacuoles 299

Leukocytoclastic vasculitis 83f, 417, 686, 748, 755, 755f, 756t, 959

Leukoencephalopathy, progressive multifocal 2032

Leukonychia 1276

classification of 1277

hereditary 1277f, 1292

partial diffuse 1277f

spotted 1277f

Leukoplakia 1334f

oral 324f, 343f

Leukotriene 36, 229

Lhermitte–Duclos disease 1422

Lice 1898

Lichen

nitidus 539, 539f

planopilaris 1205, 1205f

planus 82f, 530, 531f, 533f, 534, 1316, 1781, 2028

annular 533f

histopathology of 533f

oral 2033

papules of 533f

pemphigoides 666, 671

ungual 1267f, 1284, 1284f

sclerosus

disease 795, 796f, 1304, 1305, 1305f

et atrophicus 1120

scrofulosorum 1739

simplex chronicus 631, 631f

spinulosus 540, 540f, 585f

striatus 534, 535f

histopathology of 536f

Lichenification 581f

Lichenoid 82, 548

dermatitis, annular 537, 691

drug eruption 1781

inflammatory process 536f

Licorice 2098

flavonoid 2098

Lidocaine 1807, 2105

Ligase chain reaction 1948

Lightbulb sign 579

Light-emitting diode 2072, 2083

Lightning injuries 1604

Limb

defects 380, 386, 403

nevus 395

upper 1882f

Limb–Mammary syndrome 304, 305, 316, 321

Lindane 1902, 1909

Linear IgA disease 91f, 2035

Linear skin defects 386

Linear ubiquitin assembly chain, components of 840

Linoleic acid 881

Linuche unguiculata 1618

Lip

lentigines 1584f

lower 149f

mid-upper 1309f

pits, congenital 187

swelling 957f

thick everted 306f

Lipase maturation factor 881

Lipids

epidermal 10

laden macrophages 1084f, 1441f

Lipoatrophy 1084f

Lipoblastoma 1540

Lipoblastomatosis 1540

Lipodermoid 406f

Lipodystrophia centrifugalis abdominalis infantalis 1085

Lipodystrophy 333, 839, 842, 844, 935, 936t, 940, 1080, 1085, 1086

acquired

generalized 1086

partial 1086

congenital generalized 1086

familial partial 331, 935, 1086

local 939

multifocal 812

syndrome 333

panniculitis induced 843, 1085

Lipofibromatosis 1527, 1527f, 1540

Lipogranulomatosis, disseminated 908

Lipoid proteinosis 909, 1332

Lipoma 1539

multiple 1539t

Lipomatosis 1539

Liponyssoides sanguineus 1715

Lipopolysaccharide 45, 1936

Lipoprotein

cholesterol

low high-density 937

low-density 937

high-density 2050, 2054

intermediate density 879

lipase 881

low-density 498, 878, 1200, 2050, 2054

metabolism, disorders of 878

very-low-density 881, 937

Liposarcoma 1571

Lipoxygenase system 2098

Liquid nitrogen 1989

Liquor carbonis detergens 1980

Listeria 1707

monocytogenes 164, 460, 476, 1707, 1727

infection 164

Little toe, double nail of 1290

Livedo racemosa 825

Livedo reticularis 698, 698f, 699, 699t

idiopathic inflammatory 699

physiologic 699

Liver

disease 824, 884, 963, 2021, 2034, 2054, 2122

history of 2019

severe 739

function tests 2012

Loa loa 1887

Lobar panniculitis 86f

Lobomycosis 1861

Local anesthetics, eutectic mixture of 2075, 2105

Localized alopecia syndromes 1168, 1169

Locus heterogeneity 61

Loeys–Dietz syndrome 1050, 1069, 1491f

Löfgren's syndrome 971

Longer disease 795

Loose anagen hair syndrome 1196, 1197f

Loricrin keratoderma 255, 264, 265f, 1043

Loricrin mutations 264

Lower lip 149f

congenital fistulae of 1306

sucking calluses in 150f

Loxosceles 1655

reclusa 1655f

spiders 1655

Lucio's phenomenon 1751

Lucky luke dermatitis 620, 620f

Lucky syndrome 1157

Lumbar syndrome 1364, 1365, 1366f

Luminal cells 21

Luminal neutral amino acid 875

Lung disease

interstitial 817, 965, 2041

severe chronic 336

Lupoid leishmaniasis 1882, 1882f

Lupus erythematosus 429, 509, 670, 783, 787f, 1020, 1057, 1121, 1328, 1600f, 1642, 1674, 1998, 2028

linear 786f

neonatal 70, 664, 692, 790, 791f

panniculitis 1082

subacute cutaneous 111f, 429, 784, 2043

tumidus 785

Lupus

panniculitis 1082, 1083f

tumidus 785f, 787f

vulgaris 1739, 1739f

Lyme arthritis 1717

Lyme borreliosis 1470

Lyme carditis 1717

Lyme disease 530, 693f, 693t, 1652, 1716, 1978

disseminated 692

early disseminated 692

erythema migrans of 1717f

Lymph node 1461

regional 49f

Lymphadenopathy 417, 443, 447, 1237f

Lymphangioendotheliomatosis, multifocal 745, 1364, 1422

Lymphangitis 1694, 1695

nodular 163

Lymphatic filariasis 1888

Lymphatic malformation 149, 1347, 1352, 1392

Lymphedema 1387

bilateral 372f

Lymphocyte 83f, 1084f, 1436f

antigen, cutaneous 46, 49, 50

function antigen 445

small accumulations of 1462f

specific protein tyrosine kinase 41

trafficking 45

Lymphocytic infiltrate 786

Lymphogranuloma venereum 1918, 1951, 1952t

Lymphoid

cells 31

tissues 31

Lymphoma 1239, 1459, 1465

marginal zone 1468

primary cutaneous 1459

systemic 1469

Lymphomatoid papulosis 547, 1463, 1465f

subtypes of 1466

Lymphopenia 1810

Lymphoplasmacytic plaque 1009

Lymphopoietin, thymic stromal 577, 588

Lymphoproliferation 426t

Lymphoproliferative disorder 1465

Lymphotoxin alpha 2044

Lyngbya majuscula 1617

Lysine catabolism, disorders of 876

Lysosomal acid lipase 879

deficiency 2122

Lysosomal enzyme alpha-l-iduronidase 905

Lysosomal storage

disease 903, 2120

disorders 2115, 2121t

Lysosome 2120

Macrocystic lymphatic malformation 1352f

Macroglossia 918f, 1310

primary causes of 1310t

secondary causes of 1310t

Macrolides 2015

Macrophage 31, 37, 43, 50f

activation syndrome 822, 824, 1444

Macular dystrophy

juvenile 293, 1166

syndrome 305

Macular erythema 1239

Macular pigmentation, idiopathic eruptive 1136, 1137

Macules 71f

bilateral depigmented 1111f

erythematous 137f, 683f

hypomelanotic 357

hypopigmented scaling 1433f

large hyperpigmented 1130f

multiple hyperpigmented 1109f

red-brown 1442f

Maculopapular

drug reaction 1667

exanthem 1667f, 1762f

rash 1667

MaCune–Albright syndrome 61, 354, 920, 942, 942f, 1130, 1130f, 1156

Madurella mycetomatis 1856, 1857

Maffucci syndrome 1414

Majocchi's granuloma 86f, 106

Malar rash 784f

Malassezia 526, 138, 1235, 1843, 1846, 1854, 1987, 2068

furfur 1118, 1142, 1242, 1256, 2020

globosa 1118, 2097

infections 1843

sympodialis 1118

Malathion 1902

Malformations

congenital 1582

venous 1350, 1387

Malignancies

hematologic 958

hematolymphoid 1464

Malignant melanoma 1574

dermoscopy of 1557f

Malnutrition, severe acute 1121

Malouf syndrome 331

Mammary duct ectasia 1257, 1257f, 1495

Mandible, relative protuberance of 1928

Mandibuloacral dysplasia 331, 935

Mansonella

ozzardi 1888

streptocerca 1888

Maple syrup urine disease 875

Maquas 1622, 1633

Marasmus 950, 950f

Marburg virus 743

Marfan syndrome 735, 1067, 1069, 1070

arachnodactyly in 1068f

Marie Unna hypotrichosis 1166

Marinesco–Sjögren syndrome 1173

Maroteaux–Lamy syndrome 908, 2121

Marshall's syndrome 763, 1076

Mass reduction 1768

Mast cell 31, 36, 43, 1449, 1453f, 1455, 1975

activation syndrome 2047

biology 1449

leukemia 1449

treatment of 145t

Mastigophora 1619

Mastocytosis 1449, 1454

bullous 162

classification of 1450

diagnostic criteria of 1452

diffuse cutaneous 146, 146f, 702, 1451, 1452f

erythrodermic 146, 1450

maculopapular cutaneous 1450, 1451f

nodular 694f

pediatric 1455t

skin lesions of 1450

systemic 775, 1449, 1452, 2047

treatment of 1455

Matricaria recutita 2098

Matrix

alterations of 1264

metalloproteinases 661, 1057, 2011

Mattress sutures 2107

Max Joseph's spaces 533

Maxillary bones, shortening of 1927

Maxillary dental arch 1307f

Measles 1761, 1763, 1767

atypical 1727

exanthem 1764f

Mechanical ventilation 1811

Mediterranean fever, familial 417, 835, 854, 2035

Medium-chain triglycerides 881

Medullary thymic epithelial cells 40

Mees’ lines 973

Mefenamic acid 2100

Meissner corpuscles 24

Melaleuca alternifolia 1986

Melanin 1094

synthesis 1095, 1095fc

unit, epidermal 1094

Melanocytes 10, 18, 1093

biology 1096fc

disorders of 1097

light micrograph of 18f

stimulating hormone 926, 1096, 1138

Melanocytic lesion, criteria for 96

Melanocytic nevi 1501, 1502fc

acquired 1507

compound acquired 2084

congenital 100f, 1111f, 1168, 1182, 1182f, 1501, 1503, 1504f, 1505, 1506t, 1556

extensive 2067

junctional acquired 2084

Melanogenesis 1093

Melanoma 1556, 1557f, 1562

histopathology of 1559f

invasive 95f

juvenile 1560

malignant 1574

pediatric 1558f

risk of 1503

Melanonychia, longitudinal 1278

Melanosome 1094, 2074, 2074f

Melasma 1137, 1981

Melioidosis 1733

Melkersson–Rosenthal syndrome 1328, 1329f

Melnick–Fraser syndrome 1543

Membrane attack complex 429

Memory T cells 42

MEN1 syndrome 1519

Mendelian inheritance 303

Mendes da Costa syndrome 346

Meningitis

bacterial 1727

gonococcal 1939

Meningocele 192

rudimentary 192

Meningococcal septicemia 1726f, 1727f

Meningoencephalitis 685

Menkes disease 348, 886, 886f, 1171

protein 1171

Menkes syndrome 886f, 1102

Mental retardation 210, 443, 1277

Menthol 1975

Menzies 11-point scoring method 97

Mepivacaine 2105

Mepolizumab 776

Mercaptobenzothiazole 620

Mercaptopurine 514, 2027

Mercury 1623

Merkel cells 3, 18, 19

Mesenchymal cells 6, 1532f

Mesenchymal stromal cells 2118, 2119

Messenger ribonucleic acid 56, 57, 1984, 2117

Metabolic defects 875t

Metabolic disease 2120

Metabolic disorders 568, 2120, 2122

hereditary 871

Metabolic eczema 630

causes of 630t

Metabolic syndrome 498

Metabolic wasting syndrome 239, 289, 289f

Metacarpophalangeal joint 275f

Metals 603

transport, disorders of 883

Metastasis 1574

Metastatic calcinosis cutis 971, 1021, 1022

Methicillin-resistant Staphylococcus aureus 579, 2017, 2097

Methionine 873

Methotrexate 474, 510, 592, 626, 828, 956, 2025, 2029, 2030

potential uses for 2030t

Methyl aminolevulinate 1998, 2005, 2006

Methylchloroisothiazolinone 606, 620, 2066

Methylene blue 2004

Methylisothiazolinone 599, 606, 620

Methylmalonyl-co-enzyme A epimerase encoded 875

Methylprednisolone 465, 2023

Methyltestosterone 2100

Mevalonate diphosphate decarboxylase 244

Mevalonate kinase 244

deficiency 835, 836

Mibelli, angiokeratoma of 1421

Micaceous scales 74

Micellar water 2069

Michelin tire baby syndrome 1541, 1541f

Miconazole 1839, 1854, 1987

Microbes cell 31

Microciona prolifera 1617

Micrococcus sedentarius 1709

Microdeletion

diagnosis of 55

syndromes 61, 372

Micronychia 1273, 1273f, 1274t

Microphthalmia 386

associated transcription factor 1093, 1096

Microscopic agglutination test 1736

Microsporum 1823, 1829, 1831, 1832, 2020

audouinii 101, 1824

canis 101, 1824

ferrugineum 101

Microthermal zones 2088

Microvilli-covered cells 5

Micruroides euryxanthus 1659

Micrurus fulvius 1659

Middle east respiratory syndrome 1807

Mid-face toddler excoriation syndrome 1635

Midline anterior neck inclusion cyst 181, 181f, 1490

Midline facial lesions, differential diagnosis of 191t

Migrant helminthiasis 1889

Migratory necrolytic erythema 973

Milia 151, 152f, 152t, 1489, 1491f, 1806

classification of 1490t

Miliaria 138, 1253

crystallina 139f, 1254f

rubra 139, 139f, 617f, 1254f

Miliary tuberculosis 1871

Milker's nodules 1795

Millipedes 1651

Millisecond-domain pulses 2089

Milroy's disease 1277

Miltefosine 1885

Mimic wells syndrome 776

Mind-body medicine 2100

Mineralocorticoids 925

Minocycline 1140, 1203, 2012

Minor iodine-starch test 115f

Minus nevus 1169

Mites 1653

biology of 1905

Mitochondria 9

disorders 373, 374t

encephalopathy 374

inheritance 59

Mitogen-activated protein 1096, 1097, 1390, 2025

kinase 32, 351, 391, 436, 839, 1073, 1431, 1675, 2051

Mitral valve prolapse 1065, 1068, 1069

Mitten-band hyperpigmentation 1144f

Mixed connective tissue

disease 790, 803, 852, 852t

disorder 333, 1020

MLS syndrome 314

MMP14 gene 910

Modern disposable diaper 613

Mohr syndrome 1331

Mohs’ micrographic surgery 1554

Molecular analysis 382t, 383t

Molecular tests 104, 106

Molluscipox genus 1804

Molluscum contagiosum 449f, 461, 1804, 1806f, 1961

cytodiagnosis of 106

dermoscopy of 1806f

genital lesions of 1962f

large lesions of 1962f

periocular 2083f

Molluscum dermatitis 1804

Moloney murine leukemia virus 2117

Monepidermolytic keratinocytic nevus 393f

Mongolian spot 1133

Monilethrix 1170, 1170f

autosomal dominant forms of 292

Monoamine oxidase 2021

Monoclonal gammopathy 1251

Monocyte chemoattractant protein 2042

Monogenetic skin diseases 2122

Monogenic diseases 486

Monogenic disorders 2115

Monogenic lipoprotein disorders 879t

Monomorphic lesions 1242f

Monomorphous papules 1240f

Mononuclear cells 844

Mononucleosis, infectious 1776

Mood disorders 500

Moraxella catarrhalis 1696, 1939, 2016

Moriform granulomas 1864

Morphea 795, 797, 1207

active lesions of 798f

broad linear lesions of 800f

late stage 798f

linear 797, 800f, 1120f

plaque-type 1120f

Morquio syndrome 907, 2121

Mosaic epidermal skin diseases 390

Mosaic epidermolytic ichthyosis 218f

Mosaic lesions

arrangement of 379

bilateral 384

Mosaic skin disorder 64

Mosaic Turner syndrome 371

Mosaicism 59

disseminated 379

hypopigmented 371, 1107

nonsegmental 379, 380f

patchy 380

segmental 380

superimposed 383, 383f

Moulin atrophoderma 1048

Mountain spotted fever 1701

Mouth

and genital ulcers with inflamed cartilage syndrome 770

disease 1321f

ulcers 857

Moxibustion 1622

Mucinosis, follicular 910, 910f, 1472, 1473f

Mucinous follicularis 1472

Muckle–Wells syndrome 417, 837, 913

Mucoceles 149

Mucopolysaccharidoses 905, 906t, 908, 2122

Mucor 472, 1871

Mucormycosis 1871, 1871f

Mucosa 1389

Mucosal lesions, prominent 664f

Mucosal vesiculoulcerative syndromes 1320t

Mucositis 684

chlamydia pneumoniae-induced 721

mycoplasma-induced 717

Mucous membrane 943f, 1163

anatomy 1306

diseases 1300

pemphigoid 666

Muehrcke lines 973

Muir–Torre syndrome 1582

Mulberry molars 1927

Multifocal epithelial hyperplasia 1319, 1319f

Multiorgan disease 2036

Multiple endocrine neoplasia 359, 913, 1034, 1333, 1519, 1546, 1588

syndromes 943, 944t

Multiple erythema migrans 693f, 1717

Multiple lentigines 361, 362, 1584, 1586

syndromes 2085

Multiple organ dysfunction syndrome 1610

Multisystem disease 770, 2120

Multisystem inflammatory

disease 417

disorder 837

syndrome 1810

Multisystem organ 1810

Munro nevus 400, 400f

Murray–Puretic–Drescher syndrome 1525

Muscle

benign tumors of 1540

enzymes, elevated 812

weakness, proximal 811

Muscular dystrophy 640, 642

Mutations, mechanisms of 61

MVK gene 244

Myalgia 811

Myasthenia gravis 921

Mycetoma 1855, 1857f

belt 1856

etiological agents of 1856t

Mycetome 1899f

Mycobacteria 1736

atypical 1722

infections, nontuberculous 1741

nontuberculous 1085, 1741, 1745

Mycobacteriaceae 1736, 1746

Mycobacterium 104, 1736

abscessus 1741

avium 1740

complex 1745

bovis 1740

gordonae 1745

haemophilum 1745

indicus pranii 1118

kansasii 1744

leprae 1119, 1736

marinum 989, 1614, 1616, 1621, 1732, 1742

infection 1742f

szulgai 1745

tuberculosis 104, 460, 1081, 1740

ulcerans 1743

Mycophenolate mofetil 467, 593, 2031

Mycophenolic acid 2031

Mycoplasma 1723

infections 742, 2015

pneumoniae 528, 684, 718, 721, 1081, 1930, 2012

Mycosis 104

fungoides 742, 1121, 1121f, 1460, 1461, 1462f

clinical staging of 1461t

hypopigmented 1121, 1460f

plaque type 1460f

superficial 1853

systemic 1861

Myelodysplastic syndrome 436, 761

Myelofibrosis 1435

Myeloid cells, atypical 1472f

Myeloma, multiple 56f, 974

Myocardial infarctions 498

Myoepithelial cells 22f, 23f

Myofibroma 1530f

infantile 1530f

solitary fibrous 1481

Myofibromatosis 1530

Myopathy, idiopathic inflammatory 813

Myositis

lower risk of 817

ossificans 1029

Myroxylon balsamum pereirae 604

Myroxylon pereirae 604

Myxedema 911

congenital 911f

Myxoid

neurofibroma 1128

stroma 1532f

N-acetylcysteine 1980

N-acetylethanolamine 633

N-acetylgalactosamine-6-sulfate-sulfatase 907

Naegeli–Franceschetti–Jadassohn syndrome 913

Naegleria 1885

Naftifine 1987

Nagashima's disease 632

Nager syndrome 1543

Nail 20, 533f, 1163

absence of 1273t

apparatus 1261f

bacterial infections of 1285

genetic diseases of 1291

bed 21

discoloration 493f

hemorrhage 1274

biopsy 1291

candidiasis 927f

chewing 1282

clubbing 1271f

isolated congenital 1292

composition 1263

conditions 1279

damage 1639

disease 1261

patterns 1264

disorders 1291

dyschromia, causes of 1276t

dystrophy 297f, 324f, 1264f

median 1267

severe 533f

eczema 1284

fold

capillaries 1262f

proximal 21

fragility 1269f

function 1262

grooves, multiple longitudinal 1266

growth 1263

rate 1263t

hemorrhage 1613

traumatic 1613f

landmarks of 21f

loss of 650

matrix arrest, causes of 1265t

nevi 1514

part of 1279f

patella syndrome 1289, 1289f, 1290, 1291

pitted 1266f

plate 21, 493f

alterations of 1264

separation of 493f

psoriasis 492, 493f, 1283, 1283f

signs 1272t

unit 1264f

anatomy of 1261

biology of 1261

infections of 1284

infestations of 1284

regions of 21f

Naïve T cells 49f

Nakajo–Nishimura syndrome 843, 1085

Nanocapsules 1973

Napkin

area, candidiasis of 1849f

dermatitis 611

psoriasis 492f, 825

Nappy rash 611

Nasal

bleeding 969f

cartilage, loss of 841f

chondritis 856f

crease 1242f

crease, pseudoacne of 1242

glioma 192, 192f

lubricants 969

Natal teeth 150, 1308t

Natamycin 1987

Natroba 1990

Natural killer 50t, 425, 528, 724, 1466, 1666t, 2027, 2122

cell 31, 37, 43

Naxos disease 268

NCSTN gene 764

Neck

flexors, anterior 812

lesions, verrucous 1866f

Necrobiosis lipoidica

diabeticorum 938t

severe 939f

Necrolysis, epidermal 728

Necrolytic acral erythema 963, 963f

Necrolytic migratory erythema 960, 974

Necrosis

central 1432f

epidermal 82f

Neisseria

gonorrhoeae 1935, 1936, 2015

meningitidis 743

Nemolizumab 594

Neodymium-doped yttrium aluminum garnet 2073, 2074, 2078, 2081, 2084, 2087

Neofibularia nolitangere 1617

Neomycin 626

polymyxin b-hydrocortisone 1724

Neonatal disorders 119, 144

Neonatal epidermolysis bullosa acquisita 663

Neonatal herpetic infection, primary 1784

Neonatal ichthyosis sclerosing cholangitis syndrome 299, 300

Neonatal intensive care unit 618, 1846

Neonatal sepsis, late onset 164

Neoplasm, hematological 1449

Neoplastic diseases 745

Nephrogenic systemic fibrosis 805, 971, 1675

Nestor–Guillermo syndrome 1034

Netherton syndrome 226, 237, 238f, 440, 568f, 1175, 1177f, 2115, 2120

Neu–Laxova syndrome 204

Neural crest stem cells 1093

Neural heterotopia, cutaneous 192

Neuroblastoma 1572

metastasis of 1572f

tumors staging of 1573t

Neuroborreliosis 1717

Neurodermatitis 631

Neuroectodermal melanolysosomal disease 1103

Neurofibroma 352, 353f, 357, 1544, 1545f

mucocutaneous 1128

Neurofibromatosis 351, 356, 357, 379, 1129, 1156, 1319, 1441t, 1544, 1546, 1569, 1588

segmental 71f

Neurologic diseases 685, 2045

Neurologic disorder, progressive 340

Neuroma 1546

Neuromuscular diseases, broad variety of 818

Neuromuscular disorders 2047

Neuropathy 270, 348, 1751

Neuropeptides 1250

Neuropsychiatric disorder 360

Neurothekeoma 1546

Neutral lipid storage disease 226, 232

Neutropenia 1324

transient 2048

Neutrophil 31, 37, 502f, 1084f

abundant 677f

extracellular traps 432, 840

gelatinase-associated lipocalin 1234

microabscess of 677

rich dermatoses 760t

Neutrophilia 1810

Neutrophilic diseases 759

Neutrophilic eccrine hidradenitis 1254, 1673

Nevirapine 462

Nevoid basal cell carcinoma syndrome 1551, 2052, 2123

Nevoid hypertrichosis 1180, 1180f

Nevus

anemicus 352

atypia 395

atypical 1511

comedonicus syndrome 400, 400f, 406

dermoscopic patterns, benign 1508t

dynamics of 1502f

eccrine 401

epidermicus verrucosus 404

flammeus 1389

follicular 399

lipomatosus superficialis 1538, 1538f

marginatus 399f

psiloliparus 184f, 1538, 1539f

sebaceus syndrome 404, 1510f, 1582

simplex 1352f, 1388, 1388f

spilus 1509, 1510f, 2084

treatment of 2086f

subtypes 1509

syringocapillaris 402

trichilemmocysticus 401

Next generation sequencing 62, 307, 354, 655, 1066

Nickel

dermatitis, spectrum of 604f

test kit 603

Nicotinamide 695

Niemann–Pick disease 1446

Nifedipine 804

Nijmegen breakage syndrome 420

Nikolsky sign 93

positive 726, 727

Nipple

anomalies 195

diseases 1257

eczema 585f, 1257, 1257f

Nitroblue tetrazolium 434

Nocardia 1703, 1722, 1931

brasiliensis 1856

Nocardiosis 1703

Nodular adrenocortical disease, primary pigmented 928, 1583, 1584

Nodule 72, 72f, 1227, 1311

subcutaneous 755f

Noma neonatorum 148

Nonbullous impetigo, secondary 1685f

Nonepidermolytic keratinocytic nevus 393

Non-Hodgkin's lymphomas 974, 1272, 1459

Noninvasive prenatal diagnosis tests 65

Non-Langerhans cell histiocytoses 1438, 1438t

Nonmelanoma skin cancers 472, 1551, 2025

Nonsteroidal anti-inflammatory

agents 1081

drugs 511, 684, 703, 724, 739, 756, 827, 835, 854, 1140, 1255, 1336, 1455, 1532, 1587, 1640, 1667f, 1668, 1669, 1697

Nontraumatic myositis ossificans circumscripta 1030

Noonan syndrome 65, 361, 362, 363f, 737, 1546, 1569, 1584, 1586

webbed neck in 362f

Normophosphatemic familial tumoral calcinosis cutis 1025f

N-palmitoylethanolamine 633

Nuclear factor kappa B 32, 303, 392, 486, 839, 1975

Nucleic acid amplification tests 1807, 1938

Nucleotide

binding oligomerization domain 33, 843, 858

excision repair 57, 1153

polymorphism 62

reverse transcriptase inhibitors 462

Nutrition 15

Nutritional disorders 918, 943

acquired 630

Nymph, second instar stage of 1899f

Nystatin 1987

ointment 1976

topical 1987

Obesity 497

Occipital horn syndrome 886, 888

Ochronosis 874

Ocimum gratissimum essential oil 1986

Ocular mucous membranes

anatomy of 1300f

disorders of 1300

Oculocerebrocutaneous syndrome 314

Oculodentodigital dysplasia 270, 296

Oculoectodermal syndrome 184, 374, 406

Odontoonychodermal dysplasia 304, 305, 314, 315f, 1291

Oenothera biennis 2099

Ofuji's disease 911, 1204

Oligoarthritis 824

Olindias sambaquiensis 1616

Olmsted syndrome 265, 265f

Omalizumab 2046

joint task force 2047

Omenn syndrome 440, 446, 448, 448f, 569f

Onchocerca volvulus 1887, 1888, 1910

Onchocerciasis 1119

control programme 1888

Onion skin appearance 25f, 1750

Onychauxis 1269

Onychmycosis 1840f

Onychodystrophy 444f

factitial 1639

Onychogryphosis 1269, 1269f

Onycholysis 1264f, 1274

Onychomadesis 1265, 1265f

Onychomycosis 1285, 1838

topical therapeutic options for 1841t

Onychophagia 1282, 1282f

Onychorrhexis 1267, 1267f

Onychoschizia 1268

traumatic 1268f

Onychoteiromania 1283

Ophthalmia

neonatorum 1939, 1940, 1951

prophylaxis 1949

Ophthalmopathy 921

Optical cavity 2073

Optical coherence tomography 112

Opuntia ficus-indica 989

Oral candidiasis 1323

acute atrophic 1324

forms of 1849

Oral mucosa 1313

benign tumors of 1311

infectious diseases of 1318

lesions of 1336f

pigmented lesions of 1334t

Oral mucous membranes

disorders of 1306

function of 1306t

keratinization of 1306t

Oral neonatal lesions, benign 149

Oral suction over fontanelle 1622, 1633

Oral thrush 1848f

Organ transplantation 463, 2047

Organogenesis 121

Organoid epidermal nevi 397, 404t, 405

Ornithine transcarbamylase 875

Orofacial granulomatosis 957, 957f

Orphan receptor C, receptor-related 1853

Orthohyperkeratosis 214f

Orthopox variola virus 1794

Osteichthyes 1616

Osteochondrodysplasia 1177

Osteochondroma, subungual 1543

Osteocytes 1028f

Osteogenesis imperfecta 1065, 1076

Osteoma cutis 337, 1544

large plaque of 942f

management of 1029

multiple miliary 1029

plaque of 1028f

plate-like 1026, 1028, 1029f

primary 1026

secondary 1029

Osteomyelitis 1857

chronic multifocal 1243

Osteo-onycho-dysplasia, hereditary 1289

Osteopetrosis 1291

Osteopoikilia 1037f

Ota macules, acquired bilateral nevus of 1135

Ota nevus 1133, 1134, 1135f, 2086f

Otitis externa 1620, 1724

malignant 1620

Otolaryngology 516

OTULIN deficiency 1085

Otulipenia 839

Outer ear, swelling of 856f

Outer root sheath, cells of 20f

Oval nuclei 1528

Ovarian ampulla 1899f

Ovary 930

Overlap syndrome 1065

Oxiconazole 1839

Oxybenzone 1977

P5-carboxylate reductase 888

Pachydermodactyly 1525f

Pachyonychia congenita 271, 272, 1268, 1286, 1287, 1287f, 1287t, 1332, 2115

Pacinian corpuscle 25f

Paget's disease 1257

Pain

abdominal 1979

rectal 621

Pale erythema 585f

Palisaded neutrophilic granulomatous dermatitis 827

Pallister–Hall syndrome 1291

Palm, aquagenic wrinkling of 965, 966f, 1621, 1621f

Palmar

eccrine hidradenitis, idiopathic inflammatory 1611f

granuloma annulare 986f

hidradenitis, traumatic 1255f

keratoderma 267f

papules, painful 817

papulosquamous lesions 1921f

Palmoplantar

eccrine hidradenitis, idiopathic inflammatory 1610

erosions 318f

erythrodysesthesia 698

hyperkeratosis 323f

insulated 271f

severe 218f

keratoderma 255, 259t, 268, 270f, 362, 1145, 1167

acquired 276

areata 271

diffuse 255, 256, 264, 269

epidermolytic 256, 2115

inherited 276

linear 273

painful 2115

pediatric aspects of 277

striata 270

keratosis, Nagashima-type 263

pits 1581

psoriasis 489, 490f

pustulosis 492

P-aminobenzoic acid 2017

Panencephalitis, subacute sclerosing 1764

Panniculitis 85, 1080, 1083, 1085

drug-induced 1085

lipoatrophic 1084, 1084f

nodular migratory 1889

pancreatic 1082, 1083f

subcutaneous 1083, 1460, 1466

Pansclerotic morphea 797, 798

Papillary dermis 24f, 25f

Papilloma, verrucous 1312f

Papillomatosis 1143t

confluent 632, 1142, 1845

reticulated 632, 1142, 1845

Papillon–Léage–Psaume syndrome 1331

Papillon–Lefèvre syndrome 268, 268, 1043, 1332, 1333f

Papovaviridae 1796

Papular

acrodermatitis 1779

angiokeratoma 1420

lesions, crusted 1432f

purpuric gloves and socks syndrome 743, 1769, 1771, 1771f

sarcoidosis, juvenile 993

Papule 71, 72f, 173f, 676f, 1035f, 1236f, 1227, 1780f

dome-shaped 1023f

erythematous 138f, 1240f, 1790f, 1828f

follicular 1040, 1620f

inflammatory 1228f

scattered 1433f

umbilicated 1433, 1806f

verrucous 80f

Papulonecrotic tuberculid 1738, 1740f

Papulonodules 1017f

Papulosquamous diseases 483, 526

Para-aminobenzoic acid 1232, 2105

Paracoccidioides

brasiliensis 1863

lutzii 1863

Paracoccidioidomycosis 1860, 1863, 1864f

Parainfluenza virus 1773

Parakeratosis 1016f

focal 536f

mounds of 502f

pustulosa 585f, 1283, 1283f

Paraneoplastic pemphigus 664, 959, 974

Paraphenylenediamine 109, 606

Parapoxvirus 684

Parapsoriasis 548

Parasitic disease 173

Parathormone 1029

Parathyroid hormone 941, 1020

Para-toluenediamine sulfate 606

Parechoviruses 170, 1773

Parkes–Weber syndrome 1416, 1419f

Paronychia, acute 1698, 1698f

Parry–Romberg syndrome 797, 799, 1207

Parvovirus

B 1446

B19 1767, 1768, 1769t, 1773

Pasini atrophoderma 1048

Pasteurella 1662, 1734

canis 1662

multocida 1662, 1734

Patau syndrome 61, 370, 371f, 1243f

Patch 71f

test 107, 108f, 110

Patella 415f

Pathergy test 111

Pathogenesis directed therapy 2122

P-cadherin 293

Peanut allergy 578

Pearson syndrome 374, 1446

Pedal papules

bilateral 152f

congenital 152, 195

Pediatric contact dermatitis workgroup 602t

Pediatric dermatology 67, 1969, 2030t, 2104

disorders, surgical management of 2104

Pediatric mastocytosis 1455t

epidemiology of 1450

Pediatric patch testing 601

Pediatric psoriasis 505t

topical therapies for 504t

Pediculosis 1301, 1904

pubis 1904

Pediculus 1898

capitis, life cycle of 1899f

humanus corporis 1711

Peeling 75, 126

skin

disease 290

disorders 239t

syndrome 238, 239, 239f, 290, 290, 645, 1167

Pelvic

examination 930

inflammatory disease 1936

Pelvis syndrome 622

Pemphigoid

childhood 666

bullous 667, 667t

classical bullous 668f

gestationis 663, 946

neonatal 146

infantile bullous 669f

neonatal 663

Pemphigus

childhood paraneoplastic 666

disease area index 665

familial benign chronic 243

foliaceus 661, 665f

neonatal 663

herpetiformis 664

neonatal 663

vegetans 664

vulgaris 661, 664f

neonatal 663

Penicillin allergy 1933

Penicillium 1841, 2031

marneffei 1855

Pentoxifylline 695

Penttinen syndrome 332, 332f

Peptic ulcer disease 2031

Peptidase D 440

Peptidylglycine A-amidating monooxygenase 887

Perforating disorders 939, 1016f

classification of 1015t

Perianal plaque, erythematous 1692

Periderm cells 4

Periflexural exanthema, asymmetric 1781, 1782f

Perilipin 1086

Perineal erythema, toxin-mediated 621, 1703

Perinuclear inclusions, eosinophilic 286f

Periodic acid-Schiff 150, 904, 1483, 1527, 1830

Periodic fever 848, 1325

adenitis pharyngitis aphthosis syndrome 848

aphthous stomatitis, pharyngitis and adenitis syndrome 2035

syndromes 416t, 417, 706, 835, 836, 1727, 2043

Periodic syndrome 836, 1325

receptor-associated 835

Periodontitis 268

Perioral urticarial lesions 705

Periorificial dermatitis, granulomatous 1240f

Peripheral blood mononuclear cells 1772

Peripheral nerve sheath tumor, malignant 354, 1567, 1570, 1571f

Permethrin 1902, 1909

Peroxisomal disorders 208

Peroxisome proliferator-activated receptor 1225

Petechia 75, 153

Petrolatum stripes 614

Peutz–Jeghers syndrome 956, 962, 962f, 1128, 1584, 1585, 1585f, 2085

Phace syndrome 1364, 1366f, 1369

diagnostic criteria for 1365t

Phacomatosis

cesioflammea 385f

pigmentokeratotica 398, 1510f

Phagocytes 37

Phagocytic cells 31

Phakomatosis pigmentovascularis 1392

Pharmacokinetics 2018

Pharmacologic therapy 827

Pharyngitis 848, 1325, 1774

Pharynx, uncomplicated gonococcal infection of 1938

Phenolic glucuronide 2031

Phenylalanine 871

ammonia lyase 872

hydroxylase 871, 875

deficiency 871

Phenylketonuria 871

Phenytoin 1606

Phialophora verrucosa 1859

Phlebectasia 1414

diffuse 1414

Phlebotomus 1880

Phosphatase 392, 403, 1588

Phosphate, inorganic 1062

Phosphatidylinositol 41

bisphosphate 390, 392, 393, 396, 846

kinase 392, 393, 1390, 1588

triphosphate 392

Phosphodiesterase 804, 1975

inhibitor 743

Phosphoglycerate dehydrogenase 346

Phosphoinositide dependent kinase-1 392

Phospholipase 144, 846, 1848

Phospholipid synthesis defects 888

Phosphomevalonate kinase 244

Phosphorus 1029

Photoallergens 1646t

Photoallergy 1646

Photobiomodulation 2089

Photocontact dermatitis 685

Photodermatosis 2028

idiopathic 1641t

Photodynamic therapy 539, 1997, 2004–2006, 2072, 2080

Photomediated light eruption 1998

Photon emission computed tomography 1598

Photopatch testing 111

Photophobia 240f, 348f, 1167

Photosensitivity 468

diseases 1644, 1645t

idiopathic 1641

Phototherapy 155, 508, 1113, 1997, 1998

clinical studies of 2003

indications of 1997t

types of 1997f

Photothermolysis, selective 2073, 2089

Phototoxic

drugs 2000

reactions 1644, 1645f

Phototrichogram 113

Phthiriasis palpebrarum 1301, 1900, 1904

Phylloid pattern 381

Phylum porifera 1617

Physalia physalis 1615

Physical abuse 1626

Phytanic acid

oxidase deficiency 230

storage disease 230

Phytanoyl-coenzyme A hydroxylase deficiency 231

Phytophotodermatitis 1645

Piebaldism 1106, 1106f

Piedraia hortae 1854

Pierini atrophoderma 1048

Piezogenic papules 1055, 1613

Pigment

application of 1637

demarcation lines 1130, 1131f, 1131t

dilution 873

incontinence 312

network 100f

Pigmentary abnormalities, camouflaging techniques for 2068t

Pigmentation 99f

diseases 1150

disorders of 1097

regulation of 1095

Pigmented nevi, congenital 2084

Pigmented nodular adrenocortical disease 1128

Pile 1936

Pili

annulati 1175, 1176f

canaliculi 1174

torti 1171, 1171f, 1172

trianguli 1174

Piloleiomyoma 112, 1541, 1239, 1479, 1480f

deep 1480f

histopathology of 1480f

Pimecrolimus 802

Pincer nails 1271, 1271f

Pinch purpura, bizarre patterns of 1637

Pinworm infestation 1304

Piperonyl butoxide 1990

Pityriasis

alba 630, 631t, 1117, 1117f

mild 631f

lichenoides 543, 545f, 546f, 1462, 2000, 2002, 2029

acute 82f

chronica 544

et varioliformis acuta 544

rosea 540, 542f, 1833

atypical 1782

variants of 542f

rotunda 543

rubra pilaris 269, 550, 550t, 551f, 565, 565f, 812, 2029

versicolor 1843, 1845f

Pityrosporum

folliculitis 1844, 1845f

ovale 1687

septicemia 1845

Plague 1735

Plakoglobin 284, 640f, 645

junction 284

Plakophilin 285

Plane warts 1799

Plantar

dermatitis 605f

juvenile 585f, 627, 628f

fibromatosis 1524, 1524f

hidradenitis 1255

hyperkeratosis 256f

porokeratotic lesions 245f

wart 1801, 1802f

multiple small 1802f

Plaque 72, 72f, 585f

chronic 2029

erythematous 676

morphea 798f

nummular 583f

psoriasis 487, 488f, 502, 502f, 509f

classic 488f

scaly 841f

Plasma cell 43

Plasminogen activator inhibitor 738

Plasmodium falciparum 2012

Platelet

derived growth factor 331, 803, 1271

disorders 738t

Platyhelminthes 1887

Platyonychia 1270

Playstation thumbs 1610

Plectin gene 648

Pleurodynia 1774

Plexiform

fibrohistiocytic tumor 1533, 1569

neurofibroma 352, 353f, 1183

isolated 1545f

Plexus

subpapillary 7

vascular 25f

Plotosus lineatus 1616

Plummer's nail 921

Pluripotent stem cell 2117

Pneumococcus 990, 1302

Pneumocystis

jirovecii 437, 448, 476

pneumonia 2017

Pneumonia, infant 1951

Pneumonitis, nonspecific interstitial 847

Podofilox 1956

Poikiloderma 75, 329, 337, 338f

alopecia, retrognathism, and cleft palate syndrome 345

congenitale, hereditary 337

nongenetic 1158

sclerosing 345f

Poikilodermatous mycosis fungoides 1460f

Poliosis 1185, 1185t

Polyangiitis 753, 754, 965–967, 967t, 1328

microscopic 753, 2047

Polyarteritis nodosa 417, 749, 754, 755f

cutaneous 754, 755f

systemic 699

Polyarthritis 825

nonerosive 959

Polychondritis 968f

relapsing 856, 965, 967

Polycyclic aromatic hydrocarbons 1980

Polycystic kidney disease 357

Polycystic ovarian

disease 930

syndrome 498, 500, 928, 930, 936, 1208f, 1227, 1229

Polydioxanone 2107

Polyendocrinopathy 423, 445

Polyenes 1987, 1988

Polyethylene glycol 872

conjugated bovine adenosine deaminase 2122

Polygenic diseases, mechanism of 58

Polygenic skin disorders 387f

segmental mosaicism of 387

Polyglactin 2107

Polyglycolic acid 2107

Polyglyconate 2107

Polygonal cells 1530f

Polymerase chain reaction 62, 104, 148, 167, 723, 724, 801, 1007, 1284, 1319, 1382, 1562, 1620, 1690, 1711, 1721, 1827, 1884, 1935

Polymorphonuclear leukocytes 1931

Polymorphous light eruption 341, 1641, 1642f, 2033

Polyneuropathy 1251

Polyonychia 1273

Polyostotic fibrous dysplasia 942

Polyp, umbilical 193, 194f

Polypeptide gene 443

Polyposis syndrome, juvenile 962

Polysorbate 2031

Polythelia, bilateral 196f

Pomade acne 1241, 1241f

Pompe disease 2121

Pompholyx 626

Pool palms 1621, 1621f

Popliteal pterygium syndrome 1291

Porcelain nails 1292

Porokeratosis 243, 2004

classification of 244

linear 245f

palmoplantaris et disseminata 276

Porokeratotic adnexal ostial nevus 402, 403f

Porokeratotic eccrine nevus 297, 298f, 402

Poroma 1486f

eccrine 1485

Porphobilinogen deaminase 2120

Porphyria 890, 890t

acute intermittent 896

cutanea tarda 804, 890, 894, 895f, 1672, 2033

erythropoietic 1998

hepatoerythropoietic 892, 894

variegate 897f

Porphyrinemia, transient 145

Port-wine stain 801, 1389, 1389f, 1985, 1391f, 1392f, 2006, 2041, 2075, 2079f, 2080t

laser treatment of 2077, 2079f

Postaxial polydactyly 195f

Posterior brachioclavicular cutaneous nerves 1135f

Post-kala-azar dermal leishmaniasis 1118, 1881, 1884

Poststeroid panniculitis 1085