Practical CLINICAL BIOCHEMISTRY Methods and Interpretations
Practical CLINICAL BIOCHEMISTRY Methods and Interpretations
Fourth Edition
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This book has been published in good faith that the contents provided by the author contained herein are original, and is intended for educational purposes only. While every effort is made to ensure accuracy of information, the publisher and the author specifically disclaim any damage, liability, or loss incurred, directly or indirectly, from the use or application of any of the contents of this work. If not specifically stated, all figures and tables are courtesy of the author. Where appropriate, the readers should consult with a specialist or contact the manufacturer of the drug or device.
Practical Clinical Biochemistry: Methods and Interpretations
First Edition : 1995
Second Edition : 1999
Third Edition : 2003
Reprint : 2006, 2008
Fourth Edition : 2014
9789350909423
Printed at
I feel deeply indebted to all of you for giving such a tremendous response to the earlier editions of this book. It has been my sincere effort to keep on serving through each new edition.
It gives me great pleasure to introduce the fourth edition of the book titled Practical Clinical Biochemistry: Methods and Interpretations. Keeping in view the latest developments, the book has been thoroughly revised and updated. The salient features of the present revised edition comprise of the following:
- Details on evaluation and monitoring of QC data
- New diagnostic indicators of different diseases
- New chapter on therapeutic drug monitoring
- Usefulness of some tests over other tests, e.g. spot urine protein–creatinine ratio over 24 hours urine protein, serum beta trace protein over serum creatinine as indictor of reduced GFR, ionized calcium over total calcium, etc.
- Addition of different new techniques
- Vast coverage of topics to match the standard of knowledge required for MD Biochemistry students. This has resulted in its usefulness not only for undergraduates but also for postgraduate students
- Addition of 120 new case reports, increasing the total number to 370. The case reports will be of immense value for the students and teachers and in the long run bridge the gap between clinicians and clinical laboratories.
For better comprehension, the book has been written in simple, clear and easy-to-understand language. The book will equip the students with basic knowledge of applied practical biochemistry. Any suggestion and constructive comments for improvement of the book will always be welcomed. Please send your suggestions through e-mail to ranjnachawla@yahoo.com
Ranjna Chawla
Preface to the First Edition
Modern medicine is rapidly advancing and laboratory research work has provided the perfect backdrop to the process. Laboratory tests and investigations have become the mainstay of today's clinical practice so much so that the emphasis seems to be shifting from the study of patients to the study of investigative data. The importance of laboratory investigations in diagnostic and prognostic studies and thus in patient care cannot be underestimated.
In the ever-expanding field of biochemistry, it is imperative to keep abreast of the latest developments. As a student and teacher of biochemistry, I have always felt the need for a complete and comprehensive book on practical biochemistry. This book is an outcome of the experience gained by me after having worked in various laboratories at different capacities. The subject has been discussed in a lucid manner in the various chapters brought out in this book. In order to encourage a sense of participation and to instill in the laboratory workers the importance of laboratory results in the evaluation of various diseases, 115 case reports have been included at the end of last chapter. These case reports correlate biochemical findings to the medical interpretation. Recent areas of concern, such as automation, AIDS, quality control, radioisotopes and immunology, have been elaborately dealt with, so that the book would also serve medical undergraduates, teachers of biochemistry and practitioners of medical sciences.
I hope that this effort will be appreciated by all those concerned with practical biochemistry. I welcome constructive criticism and suggestions for the further improvement of this book.
Ranjna Chawla