A
Abdominal pain 310
Abnormal
constituents of urine 364
G-protein signaling 653
GTT curve 315
metabolism of copper 521
PRPP synthetase 567
Absorption of
amino acids 198
carbohydrates 106
folic acid 488
glucose 106
lipids 148
long chain fatty acids 148
vitamin
A 464
Acanthocytes 341
Acesulfame potassium 81
Acetaldehyde dehydrogenase 141
Acetate buffer 392
Acetoacetyl CoA 239
Acetylation 548
Acidification of urine 395
Acidity of solution and pH 391
Acidophils 660
Acrodermatitis enteropathica 522
ACTH stimulation 668
Action of
allosteric enzymes 62f
aspirin 189
calmodulin 504f
chemical carcinogens 707
chymotrypsin 52
epinephrine 235
hemoglobin 395
insulin on enzyme 321
medicines in gout 568f
phospholipases 90
proteases 198f
proteolytic enzymes 198t
reverse transcriptase 593f
steroid hormones 656f
vitamin
A 467f
D 472
Activity of chromatin 578
Acute
abdominal pain 275
glomerulonephritis 370
hepatitis 305
hepatocellular injury 354
illness 533
inflammation 436
intermittent porphyria 274
kidney injury 369
liver failure 353
lymphatic leukemia 309
manifestation 554
metabolic complications 326
nephritis syndrome 374
phase proteins 383
poisoning 402
radiation syndrome 738
respiratory acidosis 404
Acyclovir 61
Addisonian pernicious anemia 493
Adenine nucleotide translocase 268
Adenosyl cobalamin 492
Adenoviruses 630
Adipokines 161
Adrenal
adenoma 668
carcinoma 668
cortex 132
cortical hormones 664
hypofunction 668
insufficiency 412
Adrenaline 322
Adrenodoxin reductase 545
Aerobic dehydrogenases 257
Aflatoxins 706
Agarose 80
Age-related macular degeneration 474
Alcian blue staining 429
Aldonic acid 74
Alkaloids 555
Alkaptone bodies 238
Allergy 483
Alpha
amino
acids 24
group 226
helix 37
methenyl bridge 277
methyldopa 235
oxidation 155
secretases 729
thalassemias 294
tocopherol 473f
Aluminum toxicity 552
Amanita phalloides 589
Amantadine 621
Ame's test 614
Amide formation 30
derivatives of importance 30
metabolism 347
oxidation 479
pool 201f
profile in HPLC 451f
sequence
number 284
of globin 284t
substitution 290
transport 217
with amide groups 25f
Amino
isobutyric acid 571
Aminoacidurias 245
Aminoguanidine 330
Aminolevulinic acid 281
Aminopterin 491
Amniocentesis 140
Amniotic fluid 422
Amyloidosis 690
Amylopectin 78
Anabolic steroids 412
Analogs purine synthesis inhibitors 565
Anaphylaxis 244
Anaplerotic role of TCA cycle 253
Andersen's disease 144
Androgen binding protein 670
Angina pectoris 228
Angioneurotic edema 692
Angles of rotation in peptide bond 34f
Angular stomatitis 480
Anion gap 399
Anomeric carbon atoms 72
Anomers of D-glucose 71f
Anserine 215
Antagonists of nitric oxide 228
Antibody dependent cell mediated cytolysis 687
Anticodon arm of tRNA 597
Anticonvulsant therapy 508
Antiglomerular basement membrane antibody 375
Anti-HIV drugs 703
Anti-insulin hormones 323
Antimalarial drugs 133
Antimicrobial techniques 645
Antineutrophil cytoplasmic antibody 375
Antioncogenes 710
Antioxidants 438
Antiphospholipid syndrome 388
Antiport system 362
Anti-retroviral therapy 704
Antisense therapy 595
Antithrombin deficiency 387
Antithyroid drugs 673f
Anti-TNF therapy 696
APL antibody syndrome 92
Apoferritin 517
Apolipoprotein 173
Appearance of albumin 361
Applications of
bioinformatics 644
cloning of
animals 636
plants 636
diuretics 363
glycolytic enzymes 117
isotopes in medicine 732
lysosomes 12
molecular cloning in medicine 636
monoclonal antibody 641
PCR 639
radioactivity
for diagnosis 736
in treatment 736
recombinant technology 624
Aquaporins 18
Arabinose 76
Arcuate nucleus 660
Argemone mexicana 555
Argentaffin cells 241
Argentaffinomas 241
Arginase deficiency 206
Argininemia 431
Arsenic toxicity 552
Arthritis 567
Arthur Harden 107
Ascitic fluid 423
Asparaginase 225f
Assessment of
acid-base parameters 404
adrenal androgen secretion 668
B12 deficiency 494
deficiency 468
Folate deficiency 490
gastric function 357
glucocorticoid secretion 667
hyperkalemia 416
hypernatremia 414
hypokalemia 416
hyponatremia 414
pancreatic function 358
sodium 410
water balance 410
Asthma 404
ATP synthase 264
Augmented histamine test 357
Automated photometric analyzers 457
Automatic sequencing 40
Avidin 486
Azotemia 370
B
Babinski's sign 494
Bactericidal action of penicillin 16
Bacteriophages 626
Balanced polymorphism 611
Bantu siderosis 520
Barlow's disease 497
Bartter syndrome 20
Becker's muscular dystrophy 631
Beckwith-Weidmann syndrome 623
Beer-Lambert law 455
Bell shaped curve 58
Benign familial hypercalcemia 508
Benzene 26
Benzoquinone acetate 238
Beriberi 478
Beta
alanine 215
amino acids 198
chain of chorionic gonadotropin 713
glycosidic linkage 77
oxalyl amino alanine 555
oxidation 153
of fatty acids 151
thalassemia 293
Bevacizumab 718
Bhopal gas tragedy 554
Bial's test 317
Biliverdin 277
Biochemical
analysis of CSF 422
effects of vitamin D 470
functions of
inositol 495
polyamines 229
vitamin A 467
vitamin C 496
role of vitamin
A 465
E 473
K 475
Biogenic amines 230
Biomarkers for kidney diseases 369
Biomolecules 4
Biosynthesis of
ascorbic acid in animals 496
cholesterol 170
glycoproteins 143
heme 271
insulin 318
prostaglandins 189
purine nucleotides 563
Birth defects 490
Bisphenols 553
Bitot's spots 467
Black liver jaundice 280
Blackening of urine 238
Bladder tumor antigen 715
Blood
ammonia 354
brain barrier 381
cells 632f
flow experiments 735
group substances 143
phenylalanine 237
transfusion 693
urea nitrogen 370
vessels 228
Bone 504
deformities 472
in rickets 472f
demineralization 509
marrow 353
mineral density 510
mineralization 509
osteoblasts 470
scanning 736
Bovine spongiform encephalopathy 728
Brachytherapy 737
Branching enzyme 125
Breast milk jaundice 280
Brittle bones 722
Bromide intoxication 401
Bromsulphthalein excretion test 354
Bronchitis 404
Bronchodilator 190
Bronchopneumonia 403
Bronchopulmonary dysplasia 436
Bronze diabetes 520
Buffering against acid load 396
Burkitt's lymphoma 708
Burning foot syndrome 485
Butyric acid 85
C
Cadaverine 230
Cadherins 740
Caenorhabditis elegans 629
Caesium 735
Cahill cycle 120
Calcinosis 473
and muscle contraction 725
based signal transduction 654
channel blockers 20
disodium versenate 552
homeostasis 506f
in blood 505
in cells 503
load test 508
pump 20
Calnexin 144
Calomel electrode 457
Calorie requirement 538
Calpains 504
Calpastatin 505
Calreticulin 144
Calsequestrin 726
Carboxyhemoglobin 289
Carboxyl proteases 52
Carboxylase 154
Carboxypeptidases 198
Carnosinuria 215
Carpopedal spasm in tetany 509f
Casal's necklace 481
Caspase activation cascade 616
Catabolic pathway of hemoglobin 277f
Catabolism of
branched chain amino acids 230t
glycoproteins 145
heme 276
phenylalanine and tyrosine 233f
pyrimidines 572f
serine 214
serotonin 241
thyroid hormones 674
tyrosine 233
Catechol-O-methyl transferase 236
Cathepsins 199
Causes of
acid-base disturbances 404
acquired porphyrias 276t
adrenal insufficiency 668
anemias 295
B12 deficiency 493
cholestatic liver disease 351
fat deposition in liver 162
fatty liver 162
hepatocellular damage 351
hypercalcemia 508
hyperkalemia 416
hypernatremia 412
hyperphosphatemia 512
hypocalcemia 508
hypokalemia 415
hypomagnesemia 513
hyponatremia 412
hypophosphatemia 512
iron deficiency 518
jaundice 351
oxaluria 213f
renal tubular acidosis 401
Celiac disease 150
Cellular
buffers 397
immune deficiency 692
movements 726
repair 645
respiration 255
theories of aging 730
Cerebral beriberi 478
Cerebrospinal fluid 421
Cetavlon test 429
Cetuximab 718
Channel protein 19f
Charley Chaplin gait 221
Cheilosis 480
Chemiosmotic theory 263
Chemotroph 256
Chloramphenicol resistance gene 627
Chlorodinitrobenzene 218
Chlorpropamide 351
Cholecystectomy 360
Cholelithiasis 351
content of food items 532t
degradation 674
efflux regulator protein 180
ester transfer protein 180
pool in liver 173f
synthesis 171f
Cholinesterase 307
Chorionic villus sampling 425
Chovstek's signs 524
Christmas disease 386
Chromatography 448
Chromosomal disorders 611
Chronic
alcoholism 141
complications of diabetes mellitus 328
diarrhea 512
glomerulonephritis 436
illness 533
inflammation 436
liver disease 355
lung disorders 292
lymphocytic leukemia 715
pulmonary diseases 288
pyelonephritis 370
recurrent infections 326
renal failure 412
respiratory acidosis 404
Chylothorax 150
Chyluria 150
Chymotrypsin 197
Chymotrypsinogen 59
Circulating leukocytes 353
Cis and trans forms of fatty acid 85f
Cistron 693
Citrulline 206
Class of jaundice 349
Classification of
acid-base disturbances 398
amino acids 24
anemias 518
enzymes 48
fatty acids 85t
hypolipoproteinemias 342t
jaundice 349t
liver function tests 348t
mutations 612
prostaglandins 188
proteins 42
renal function tests 361
Cleavage of aromatic ring 233
Clindamycin 605
Clomiphene citrate 669
Cobalophilin 492f
Cockcroft-Gault equation 368
Co-enzyme
activity of
biotin 485
pantothenic acid 484
riboflavin 479
forms of niacin 480
functions of folic acid 488
of fatty acid synthesis 159
Colchicine 568
Collagen helix 38
Color blindness 466
Colorectal cancers 713
Colostrum 421
Coma 166
Combining stem cells and gene therapy 631
Common
amino acids 26t
industrial pollutants 554t
monosaccharides 70t
pyrimidines 560f
sugar substitutes 81
therapeutic uses of monoclonal antibodies 641t
Compare oxygen with superoxide anion 433f
Compensated metabolic acidosis 402
Composition of
buffer 392
cerebrospinal fluid in health and diseases 422t
milk 420t
nucleotides 559
nutrients in common food materials 758
Compound lipids 83
Concept of carcinogenesis 713f
Cones for color vision 466
Congenital
cataract 139
disorders of glycosylation 144
hyperbilirubinemias 279
methemoglobinemia 289
spherocytosis 280
Conn's syndrome 668
Conservation of iron in body 518f
Constituents of gastric secretions 357
Contractile proteins 723
Corneal arcus 342
Corrin ring 491
Corticosteroid stressed GTT 316
Cosyntropin stimulation 662
Co-translational glycosylation 603
C-reactive protein 383
Creb binding protein 657
Creutzfeldt-Jakob disease 728
Cruetzfeldt-Jakob disease 606
Cryoglobulinemia 374
Crystallins 727
C-type natriuretic peptide 304
Cumulative sum chart 444
Cutanea tarda 274
Cyanogenic glycosides 555
Cyanopsin 466
Cyanosis 289
Cycle of events in muscle contraction 725f
Cycloheximide 605
Cyclophilin 268
Cyclophosphamide 717
Cystathionase deficiency 221
Cystathionine beta synthase deficiency 221
Cytidine 561
Cytomegalovirus 375
D
Dark adaptation time 466
Deficiency
in weight for height 535
manifestations of
pyridoxine 483
thiamine 478
vitamin A 467
vitamin C 497
vitamin E 474
Deficiency of
biotin 486
enzymes of salvage pathway 567
fructokinase 317
galactose-1-phosphate uridyl
transferase 317
glycolytic enzymes 117
HBA 294
insulin 165
magnesium 508
pantothenic acid 485
vitamin
K 475
Degradation of
adrenaline 236
collagen 722
cysteine 217
glycogen 124
insulin 319
proline 244f
pyrimidine nucleotides 571
Dementia 481
Denaturing high performance liquid chromatography 643
Density gradient centrifugation 448
Dental caries 530
Deoxyribonucleoside phosphates 562
Deoxyribose 76
Depletion of glucose 311
Depresses glycogen 313
Depressive psychosis 241
Desaturation of fatty acids 186
Desulfhydrase 20
Determination of glucose in body fluids 312
Dextrose 71
Di acyl glycerol 655f
Diacylglycerol pathway 655
Diastereoisomers of glucose 71
Dichlorodiphenyltrichloroethane 553
Dickens-Horecker pathway 129
Dietary
carbohydrates 530
deficiency of tryptophan 482
sources of
niacin 482
riboflavin 480
vitamin A 469
vitamin B6 484
vitamin C 498
Diet-induced thermogenesis 529
Digestion 5
in intestines 147
in stomach 147
of carbohydrates 105
of lipids 147
of medium chain fatty acids 184
of nucleic acids 563
of proteins 196
of triacylglycerols 148
Dihydrofolic acid 572f
Dihydrotestosterone 670
Dihydrouridine 597
Diisopropyl fluorophosphates 61
Dilutional hyponatremia 409
Dipalmitoyl lecithin 91
Dipeptidases 198
Diphillobothrium latum infection 494
Diphtheria toxin 605
Disorders of
branched chain amino acids 428
heme synthesis 274
histidine metabolism 428
proline and hydroxyproline 428
urea cycle 205
Disposal of ammonia 203
Distribution of iron 514
Diuretic therapy 404
Dixon plot 57
Docosahexaenoic acid 184
Dopa-decarboxylase 235
Dopamine 235
Double reciprocal plot 57
Down syndrome 324
Doxorubicin 267
Duodenal ulcer 357
D-xylose absorption test 359
Dysuria 296
E
Ecchymoses 498
Ectopia lentis 221
Ectopic secretion of tumors 508
Eicosanoids 188
Eicosapentaenoic acid 184
Electrolyte imbalance 410
Electromagnetic waves 734
Electrospray ionization 458
Electrostatic bonds 5
Elemental mercury 552
Embryonic hemoglobins 289
Emission spectroscopy 456
Emphysema 352
Endocarditis 374
Endocytic vesicle 21
Endogenous triglycerols 177
Endorphins 662
Enzymatic method 313
containing metals 51
contains heme 227f
deficiencies in porphyrias 275f
engineering 66
indicating hepatocellular damage 353
multiplied immunoassay technique 454
profile in liver diseases 305
theory 53
Epidemic dropsy 556
Epimerism of aldoses 71
Epimers of D-glucose 71f
Epstein-Barr virus 708
Eruptive xanthomata 342
Erythroblastosis fetalis 280
Erythrodextrin 78
Erythrodontia 275
Estimation of urinary free cortisol 667
Estradiol 669
Estrogen receptor 715
Etanercept 696
Ethylenediaminetetraacetic acid 442
Eukaryotic cell 5
Euthyroid goiter 676
Ex vivo gene therapy 630f
Examples of
allosteric enzymes 63t
competitive inhibition 568f
hydrolysis 547f
stereospecificity 65f
Excessive mobilization of fat 162
Exocrine glands 243
Exocytosis 22f
Extensor plantar reflex 494
F
FAB portion 688
Familial
adenomatous polyposis 707
hypercholesterolemia 631
hyperlipoproteinemias 336
hypo beta lipoproteinemia 342
Fasting blood sugar 313
Fatal familial insomnia 728
Fate of
carbon skeletons of amino acids 244
chylomicrons 150
conjugated bilirubin in intestine 278
glucose-6-phosphate 109f
propionyl CoA 154
Favors glycogen synthesis 313
Ferrochelatase deficiency 275
Ferroprotoporphyrin 271
Ferrous iron 515
Feulgen staining 76
Fibrinogen 385
Fibrocystic disease 359
Fibrosis 163
Finasteride 670
Fine regulation of lac operon 618
Finger printing method 40
First law of thermodynamics 7
Fish tapeworm 494
Flavonoids 499
Flavoproteins 479
Fluorescence activated cell sorter 458
Fluorescent immunoassay 454
Formaldehyde 553
Formation of
active
methionine 216f
sulfate 219
alpha ketoglutarate 248
ammonia 200
AMP 563
arginine 204
argininosuccinate 204
bile
acids 182
salts 181f
branches in glycogen 125f
carbamino compound 30
carbamoyl phosphate 203
citric acid 248
citrulline 204
disulfide bridges 30f
dopa quinone 234
esters 75
free radicals 435f
fumarate 248
glutamine 30f
glutathione 217
indolequinone 234
isocitrate 248
malate 248
serine 214f
succinyl CoA 248
taurine 219
vitamin D 469
Fossil studies 639
Fractional
excretion of
bicarbonate 374
phosphate 374
sodium 374
tubular reabsorption of phosphate 374
Fractionation of doses 737
Friedreich ataxia 324
Fructokinase 137
Frusemide 363
Fumaryl acetoacetate hydrolase 239
Functions of
albumin 380
calcium 503
carbohydrates 69
cholesterol 169
citric acid cycle 247
collagen 722
copper 521
glycogen 123
glycoproteins 145t
immunoglobulins 689t
kidney 361
lipids 83
magnesium 512
muscle and liver glycogen 123f
phosphate ions 511
pyridoxal phosphate 482
pyridoxine 482
serotonin 240
sulfur 513
thiamine 482
tubules 362
Fungal infections 555
Futile cycling of lipids 536
G
Gangliosides 92
Gastrectomy 316
Gastric
and pancreatic function tests 356
atrophy 493
carcinoma 357
cell hyperplasia 357
digestion of proteins 197
function tests 356
inhibitory polypeptide 680
lipase 147
Gastrin 357
Gastritis 357
Gel filtration chromatography 450
Generation of
bilirubin 276
calcitriol 470f
cyclic amp 127
free radicals 434
nerve impulse 465
one-carbon groups 207
reducing equivalents 132
succinate 248
Genetic heterogeneity of virus 703
Gerstmann-Straussler-Scheinker disease 728
Gibb's free energy concept 7
Globin chain 290
Globular proteins 43
Glucokinase 109
Glucosamine 142
Glucuronides 317
Glycation of proteins 478
Glyceraldehyde 3-phosphate dehydrogenase 257
Glycerol 3-phosphate shuttle 260
Glycogenesis 125
Glycolipids 92
Glycosuria 317
Gmelin's test 279
Golberg-Hogness box in eukaryotes 589
Gonadotropins 662
Gopalan's burning foot syndrome 485
Grading of chronic kidney disease 369t
Guanidoacetic acid 211
Guanosine 561
H
Haemophilus influenzae 629
Haptoglobin transferrin 355
Hardy-Weinberg law 610
Harrison's sulcus 472
Hawkinsinuria 239
Hay's test 350
Heal wounds 499
Hematopoietic stem cell transplantation 631
Hematuria 365
Hemochromatosis 520
Hemoglobinopathies 290
Hemosiderin 517
Henderson-Hasselbalch equation 392
Heparan sulfate 143
Hepatic
coma 206
encephalopathy 354
lipase 344
porphyrias 274
scavenger receptor 180
triglyceride lipase 180
vein thrombosis 348
Hepatorenal tyrosinemia 239
Hermansky-Pudlak syndrome 729
Herpes simplex virus 621
Hers' disease 144
Heterocyclic amino acids 24
Heteroduplex analysis 641
Heteronuclear mRNA 591
Heteropolysaccharides 70
High
anion gap 404
metabolic acidosis 400
blood sugar stimulates insulin secretion 322f
energy phosphate bond 111
mobility group box protein 742
pressure liquid chromatography 450
sensitivity C reactive protein 338
voltage electrophoresis 448
Higher organization of DNA 576
Hill equation 58
HLA antigens 693
Hodgkin's disease 375
Homeostasis of blood glucose 312f
Homogentisate oxidase 237
Homopolymer tailing 627
Homopolysaccharides 70
Hopkins-Cole test 31
acting adenylcyclase 653
binding activates G-protein 651f
inhibit adenylcyclase 653
stimulate adenylcyclase 653
Host DNA of human cervical cancer cells 709f
Human
immunodeficiency virus 701
oncogenic viruses 708t
papilloma virus 709
placental lactogen 663
prion diseases 728
recombinant proteins 628
T cell leukemia virus 107
Hybrid cells 640
Hybridoma 98
Hydrolases 49
Hydroperoxidases 258
Hydroxycobalamin 492
Hydroxyeicosatetraenoic acid 191f
Hydroxyfatty acids 85
Hydroxyindoleacetic acid 239
Hydroxylases 258
Hydroxylation of proline and lysine 497
Hydroxyproline 244
Hydroxypyruvate 214
Hyperargininemia 206
Hyperemesis 165
Hyperhydroxyprolinemia 244
Hyperkalemic periodic paralysis 416
Hyperkeratosis 468
Hyperlipoproteinemia 343
Hyperlysinemias 226
Hypermagnesemia 513
Hypermethioninemias 220
Hypernatremia 412
Hyperosmolar nonketotic coma 328
Hyperphenylalaninemias 428
Hyperprolinemia 431
Hypo-alpha-lipoproteinemia 342
Hypochloremia 417
Hypochloremic alkalosis 402
Hypochromic microcytic anemia 294
Hypogammaglobulinemia 691
Hypoglycemic hormone 311
Hypolipidemic drugs 340
Hypolipoproteinemias 341
Hyponatremia 412
Hypopigmentation 236
Hypopituitarism 675
Hypoproteinemia 382
Hypothalamus 537
Hypouricemia 568
Hypoventilation 403
Hypovolemia 410
Hypoxanthine 560
Hypoxia 292
I
Identification of virus infection 621
Imidazole aminoaciduria 244
Immobilized enzymes 309
Immunology of AIDS 702
Immunoselection of virus 703
Importance of
carbohydrates 530
creatinine clearance 367
glucuronic acid pathway 134
proteins 532
pyruvate dehydrogenase 116
urea clearance 369
In situ hybridization 635
In vitro synthesized-protein assay 642
Indole ring 240
Infarction 335
Infliximab 696
Infusion of fluids 411
Ingram's technique 40
Inherited disorders 155
Inhibition of cell division 730
Inhibitors of
ATP synthesis 265
DNA replication 586
oxidative phosphorylation 265
protein synthesis 605
in mammals 605
TCA cycle 254
Initial number of cells 737
biosynthesis 318f
dependent diabetes mellitus 323
injections 330
like growth factor receptor 742
signaling pathway 656
therapy 512
Insulinoma 331
Integral membrane proteins 16
Integration of major metabolic pathways 251
Internal hemorrhage 498
Interpretation of
blood urea value 370
creatinine clearance 368
gastric juice analysis 357
glycohemoglobin values 329
urea clearance value 370
Interrelations of amino sugars 142f
Intralysosomal accumulation 145
Intravenous GTT 316
Ionization of aspartic acid 28f
Ionized calcium 505
Ionophores 19
Iron
absorption 517
containing proteins 514t
deficiency 518
produces free radicals 435f
sulfur complexes 514
toxicity 520
vessels 520
Ischemia modified albumin 305
Ischemic heart disease 342
Isohydric transport of carbon dioxide 287
Isoniazid 482
Isonicotinic acid hydrazide 60
Isopentenyl pyrophosphate 171f
Isosthenuria 373
Isotope dilution technique 735
K
Kartagener's syndrome 724
Karyorrhexis 163
Kaschinbeck disease 523
Keshan disease 523
Kill bacteria 185
Kinase phosphorylates enzymes 652
Kjeldahl's procedure 44
Klinefelter syndrome 324
Klotho protein 505
Kornberg's enzyme 580
Koshland's induced fit theory 54f
Kwashiorkor 535
L
Lactalbumin 420
Lactosuria 317
Lactosyl ceramidoses 193
Lambert's law 455
L-amino acid oxidase 202f
Large offspring syndrome 623
L-asparaginase 717
Late protein synthesis 621f
Latent jaundice 278
Lathyrus sativus 555
Left ventricular hypertrophy 336
Leigh's syndrome 606
Lepore hemoglobin 611
Leuconostoc mesenteroides 66
Leukoderma 234
Leukopenia 490
Levels of organizations of proteins 37f
Levy Jening's chart 444
Liddle's disease 20
Ligand binding domain 657
Limiting amino acid 534
Lipogenesis 321
Lipolytic enzymes in intestines 148
Liposomes 90
Lithium 524
Liver 101
adipose tissue axis 162
and gastric function tests 346
cells 307
cirrhosis 384
glycogen 123
metastases 354
mitochondria 163
regeneration 355
Lobry de Bruyn-van Ekenstein transformation 73f
Lovastatin 61
Low
blood sugar causes glucagon secretion 322f
carbohydrate ketogenic diet 330
HDL cholesterol 336
phenylalanine 237
Lowry's method 44
L-phosphatidic acid 89f
Luminiscence 455
Lundh test 359
Lymph node enlargement in porta hepatis 349
Lynch syndrome 585
Lynen's spiral 156
Lysinuric protein intolerance 199
Lysolecithin 90
M
Macroamylasemia 358
Macrocytic anemia 490
Macrophage 687
colony stimulating factor 696
inflammatory proteins 696
migration inhibition factor 696
Maillard reaction 328
Main functions of kidney tubules 362t
Maintaining blood sugar 311
Maintenance of nitrogen balance 533
Major catabolic pathway of tryptophan 240
Malaria 307
Malic enzyme 159
Mammary glands 132
Management of
diabetes mellitus 330
hypercalcemia 508
ketoacidosis 166
ketosis 327
metabolic syndrome 325
sickle cell disease 292
Mancini's technique 45
Marasmus 535
Marfan syndrome 222
Markers of
bone
diseases 510
formation 511
resorption 510
glomerular
filtration rate 366
permeability 371
hepatic dysfunction 349
myocardial infarction 302t
obstructive liver disease 353
Massive blood transfusions 512
Master lipid regulator in liver 160
Maternal serum alpha fetoprotein 425
McArdle's disease 144
Measurement of
alpha fetoprotein 423
bilirubin 349
glomerular filtration rate 366
osmolality 373
pancreatic enzymes 358
Mechanism of
absorption of calcium 503
action of
hormones and signaling
molecules 649
insulin 319
nitric oxide 228
PTH 506
steroid hormones 667
thyroid hormone 674
HCl secretion 356
insulin secretion 319f
regulation of pH 393
Medium chain fatty acids 184
Megadose of vitamin C 499
Megaloblastic anemia 494
Meister cycle 199f
Melanin synthesis pathway 234f
Melanocyte stimulating hormone 234
Melting of DNA 576
Membranes of organelle 16
Memory aid for essential amino acids 27
Mercury poisoning 552
Meselson-Stahl experiment 579f
Metabolic
alterations in
brain 100f
cancer cells 712
derangements in diabetes mellitus 327f
fate 228
of amino acids 245f
of pyruvate 115
functions of
cysteine 217
serine 214
junction point 117f
pathways of carbohydrates 137
profile of organs 99
traffic circle 252
Metabolism of
adipose tissue 161
alcohol 140
amino
sugars 142
arginine and ornithine 227f
ascorbic acid 496
aspartic acid 225f
catecholamines 235f
chylomicrons 176f
histamine 243f
histidine 243f
ketone bodies 163
sulfur 219
thyroid hormones 673f
tryptophan 239f
vitamin E 473
Metachromatic leukodystrophy 193
Metallo-enzymes 50
Metallopeptidase inhibitor 745
Methyl
cobalamin 492
Folate trap 493
malonic
acid 494
malonyl CoA isomerase 493
mercury 552
transfer 216
reactions 217
transferase 489f
Methylenetetrahydrofolate reductase 498
Metyrapone test 667
Micellar formation 89
Microalbuminuria 372
Microarray technique 635
Microtubules 726
Microvilli 16
Miester cycle 198
Migraine 236
Millon's test 31
Minamata disease 552
Mineral content of milk 421t
Mineralization of bone 509
Mitochondrial
cytochrome 258
DNA and RNA 605
encephalopathy lactic acidosis 606
membrane permeabilization 268
system 268
transport systems 267
Mitogen activated protein kinase 743
Mitomycin C 717
Mode of action of enzymes 51
Modifications of amino acids 603
Molecular structure of antigens 693
Molecule of polyunsaturated fatty acid 180
Mono sodium glutamate 556
Monosaccharides 69
Movement of sperms 726
Mucoproteins 81
Mucosal block theory 515
Multidrug resistance protein 278
Multifactorial disorders 611
Multiple
Multispecific organic anion transporter 278
Multistep progression 707
Mutation detection techniques 641
Myasthenia gravis 495
Mycobacterium tuberculosis 629
Myoglobinuria 295
Myotonic dystrophy 324
N
Naphthoquinone 474
Needle shaped crystals 74
Negative acute phase proteins 385
Neostigmine 61
Nephelometry 45
Nephron loss proteinuria 372
Neural tube defects 352
Neurotoxins 551
Nezelof's syndrome 692
Nickel ions 306
Night blindness 467
Ninhydrin test 430
Nitrogen balance 533
Nitrogenous substances 218
Nocturia 373
Node of Ranvier 16
Nomenclature of carbon atoms 87
Non-carbohydrate reducing compounds 317
Non-competitive inhibition 61f
Non-HDL cholesterol 338
Non-Hodgkin's lymphoma 641
Non-isotopic immunoassays 453
Non-oxidative deaminations 202
Non-phosphorylated lipids 92
Non-protein nitrogen 365
Normal
anion gap 404
composition of amniotic fluid 422t
constituents of cells 709
hydrochloric acid secretion 357t
iron kinetics 515f
oxygen atom 433f
pH 393
RBCs 291f
serum
level of magnesium 512
Normoglycemia 313
Normotonic hyponatremia 413
Nuclear receptors 657
Nucleated RBC 294f
Number of hydrogen atoms 279
Numbering of amino acids in proteins 35
Nyctalopia 467
Nystagmus 238
O
Obermeyer test 242
Oculocerebrorenal syndrome 729
Oculocutaneous tyrosinemia 239
Okazaki fragments 581
Oligosaccharides 69
Omega
Osazone formation 74
Osmolal gap 401
Osteitis deformans 354
Osteoblastoma 354
Osteoclasts 506
Osteonectin 743
Osteopetrosis 510
Osteopontin 743
Osteoporosis 510
Osteoprotegerin 743
Oxalic acid 515
Oxidation 285
of acetyl CoA 165
of fat carbohydrate 252f
of fatty acids 87
of homogentisic acid 237f
of iodine 672
of odd chain fatty acids 154
of sugars 74
products of glucose 74f
Oxidized fatty acids 336
Oxoprolinuria 199
P
Pancreozymin 197
Paracetamol 189
Paradoxic acidosis 402
Paralysis of respiratory 404
Paraventricular nucleus 660
Parenchymal diseases 353
Parent cell 579f
Paresthesia 508
Pathology of maple syrup urine disease 231f
Pauly's test 32
Penicillin 61
Pentagastrin stimulation test 357
Pentosuria 317
Penultimate carbon atom 70f
Pernicious anemia 357
Peroxidation of polyunsaturated fatty acids 438f
Peroxisomes 13
Pertussis toxin 653
Phagosomes 22
Philadelphia chromosome 708
Phosphatidates 89
Phosphatidic acid 89
Phosphatidylcholine 90
Phosphatidylglycerol 91
Phosphodiester bonds 574
Phosphogluconate oxidative pathway 129
Phosphoglyceromutase 111
Phosphoproteins 214
Photophobia 238
Phytanic acid 155
Phytic acid 515
Pineal gland 242
Pinocytosis 21
Pituitary adenoma 668
Plasma
ammonium 428
bicarbonate 405
bile acids 355
bilirubin 278
cells 686
cortisol 668
lactate 428
lipids 173
membrane 14
osmolality 373
proteins 378
Plasmacytoma 690
Plasmid liposome complex 631
Plasminogen 179
Platelet aggregation 190
Plummer-Wilson syndrome 519
Pneumocystis carinii 704
Pneumonia 404
Polarity of DNA molecule 575
Polyamine synthesis 229f
Polycystic ovarian syndrome 680
Polycythemia vera 737
Polydypsia 326
Polyneuritis 478
Polynucleotide 575f
Polypeptide 693
Polyphagia 326
Polyphenols 435
Polyuria 326
Porphobilinogen synthase deficiency 275
Porphyrin ring 271f
Porter-Silber reaction 666
Positron emission tomography scan 736
Post-hepatic jaundice 350
Poststreptococcal glomerulonephritis 375
Post-translational processing of collagen 722
Powerhouse of cell 13
Prader-Willi syndrome 324
Pre-eclampsia of pregnancy 221
Pre-hepatic jaundice 350
Preparation of specific human gene 626
Preventable blindness 468
Primary
biliary cirrhosis 351
deficit of carbonic acid 403
excess of
bicarbonate 402
carbonic acid 403
familial hypercholesterolemia 342
hemosiderosis 520
hepatoma 281
hyperoxaluria 213
hyperthyroidism 676
hypothyroidism 676
structure of
human insulin 35f
insulin 35
Production of
bilirubin diglucuronide 278f
genomic library 630f
homogentisic acid 233
hybridoma 640
niacin 483
Progression of atherosclerosis 335
Prokaryotes 570
Prokaryotic cell 5
Prolactin stimulation test 663
Proline amino peptidase 198
Prolonged in liver disease 355
Promoters of cancer 706
Propionyl CoA carboxylase deficiency 155
Prostaglandins 188
biosynthesis 596
buffer system 394
calorie malnutrition 163
catabolism 674
deficiency 533
energy malnutrition 534
misfolding diseases 729
phosphatase 127
phosphorylation 64
selectivity index 372
targeting 603
truncation test 642
Proteinuria 371
Proteolytic digestion of myosin 725f
Proto-oncogenes are regulatory genes 709
Protoporphyria 351
Pseudocholinesterase 307
Pseudouridine arm of tRNA 597
Pteroic acid 488
Pulmonary hypertension 228
Pulsed field gel electrophoresis 448
Puromycin 605
Purulent meningitis 422
Putrefaction of tryptophan 242
Pyranose ring 72f
Pyridoxamine 482
Pyrrole ring 271f
Pyrrolidine 26
Pyrrolysine 31
R
Radiation protection 738
Radium needles 737
Rancidity of fat 88
Random blood sugar 313
Rapaport Leubering cycle 115
Raynaud's disease 375
Reaction
in liver 465f
lungs 288f
amide group 30
amino acids 29
CoA derivatives 485f
cycle preparatory steps 247
glycogen phosphorylase 124f
lactate dehydrogenase 50f
monosaccharides 73
oxaloacetate 250f
Receptor mediated endocytosis 21
Reciprocal regulation of glycogenolysis 126f
Recommended daily allowance of thiamine 479
Red depicts blood 465f
Reduce dietary cholesterol 339
Reflectance spectrophotometry 457
Refsum's disease 155
Regulation of
acid secretion 357
ATP synthesis 265
beta oxidation 154
blood
glucose 311
sugar 313f
calcitriol formation 471
cholesterol synthesis 172f
citric acid cycle 253
color of skin 234
deoxyribonucleotide formation 569t
fatty acid synthesis 159
gene expression 616
gluconeogenesis 120
glycogen metabolism 126
glycolysis 112
glycosis 113f
heme synthesis 273
HMG CoA reductase 172f
HMP shunt pathway 131
ovarian hormones 669
purine synthesis 565
pyrimidine synthesis 570
secretion of HCl 356f
sodium and water balance 409
synthesis 189
urea cycle 204
Relative capacity of buffer systems 394
Renal
acid excretion 397
artery stenosis 415
blood flow 362
function tests 361
insufficiency 220
osteodystrophy 510
plasma flow 371
regulation of pH 395
rickets 472
Residual renal function 371
Retention jaundice 350
Reticulocytosis 490
Retina 20
Retinitis pigmentosa 185
Retinoic acid receptors 467
Retrolental fibroplasia 436
Reverse transcriptase PCR 639
Reversible oxidation-reduction 496
Rhodopsin 465
RIA and ELISA tests 45
Ribavirin 621
Right handed double helix 575
Romberg's sign 494
Rosenheim reaction 32
Rotor syndrome 280
S
Sakaguchi's test 32
Salivary alpha-amylase 105
Salvaging of iodine 674
Sandhoff's disease 193
Saponification 88f
Sarcoidosis 508
Sarcoplasmic reticulum 725
Schwann's cells 16
Scleroderma 375
Scurvy 497
Second law of thermodynamics 7
Secondary
hyperthyroidism 676
hyperuricemia 567
hypothyroidism 676
immunodeficiency 692
structure of proteins 36
Secretin cholecystokinin test 358
Segment of nephron 362
Selective serotonin reuptake inhibitors 240
Self-monitoring of blood glucose 458
Seliwanoff's test 317
Sensitive gel electrophoresis 642f
Sephadex chromatography 451f
Sequelae of protein calorie
malnutrition 536
Sequence of amino acids in proteins 34
Sertoli cells 670
Serum
bilirubin 355
electrophoresis 352
ferroxidase 520
globulins 352
glutamate
dehydrogenase 141
oxaloacetate transaminase 305
pyruvate transaminase 305
proteins 507
triglyceride 338
Severe hepatocellular disease 355
Sheehan's syndrome 676
Sickling test 292
Sideroblastic anemia 275
Significance of
cholesterol 334
gluconeogenesis 118
glycolysis pathway 108
heat coagulation 42
HMP shunt pathway 131
isoelectric pH 41
lactate production 112
transamination 201
Simple amino acids 25f
Site directed mutagenesis 614
Skin diseases 436
Smell of acetone 166
Sodium
channels 20
cyclamate 81
dodecyl sulfate 447
fluoride 442
hydroxide 550
ion 19f
potassium pump 19f
restriction 412
Softening of cornea 467
Soluble matrix 259
Sorensen's formal titration 29
Sources of
biotin 486
C and N atoms of pyrimidine 569f
calcium 502
carbohydrates 530t
folic acid 490
iron 514
lead poison 551
pantothenic acid 485
PUFA 532t
vitamin
D 473
E 474
K 476
Spermidine synthase 229f
Spermine synthase 229f
Sphingolipids 91
Spiranolactone 363
Split gene 693
Starch tolerance test 359
Starling hypothesis 381f
Stearic acid 85
Stimulation test 667
Streptomycin 605
Structure of
ADH and oxytocin 659f
alpha helix 37f
ATP 51f
beta-pleated sheet 37f
cholesterol 170f
chylomicrons 175f
co-enzyme 484f
collagen 720
DNA 574
folic acid 488f
hemoglobin 283
HIV 701f
immunoglobulins 687
insulin 318
lipoic acid 115f
mitochondrion 259
niacin 480f
pantothenic acid 484f
primary bile acids 181f
proteins 34
purines 560f
riboflavin 479
starch 78
sucrose 76f
T-cell receptor 694f
thiamine 477
pyrophosphate 478f
tRNA molecule 596
vitamin
A 464f
B12 491f
Subacute combined degeneration 494
Subarachnoid hemorrhage 422
Subclassification of metabolic alkalosis 402
Subluxation of lens 221
Sugars of nucleic acids 76f
Sulfate conjugation 547
Sulfuric acid 550
Surgical removal of gallbladder 360
Synthesis of
catecholamines 234
cholecalciferol 469f
CoA 484f
collagen 721
compound lipids 191
deoxythymine nucleotides 571
ferritin and transferrin receptor 516
glutathione 212
glycerophosphatides 191
glycosphingolipids 192
heme 212
leukotrienes 191f
melanin 233
mineralocorticoids 665f
nitric oxide 227
phosphatidylinositol 191
pregnenolone 664f
purines 212
pyrimidine nucleotides 570f
secretory proteins 605f
sex hormones 666f
sphingolipids 192
sphingomyelin 192
steroid hormones 664
structural and functional proteins 196
sulfatides 193
thymidylic acid 208f
thyroid hormones 236
triacylglycerols 160
triphosphates 569
Systemic lupus erythomatosus 375
T
Tamoxifen 670
Tangier disease 342
Tartaric acid 306
Tartrate resistant acid phosphatase 510
Tarui's disease 144
Tata-binding protein 590
Tendinous xanthomata 342
Testicular hormones 670
Thiazide 363
Thrombin 385
Thrombopoietin 745
Thyroxine synthesis 673f
Titration curve of glycine 28f
Trait of disease 609
Transferrin receptor protein 525
Transformation of cells in tissue culture 712f
Transforming growth factor 745
Transient glucosuria 317
Transketolase reaction 130
Transmembrane proteins 16
Transmissible spongiform encephalopathies 728
Transport
chain 255
of amino acids 219
of carbon dioxide 287
of cholesterol 335f
of glucose 320
of thyroid hormones 674
Transportation of ammonia 203
Trapping of ammonia 203
Treatment of
adenocarcinoma of colon and breast 716
hemosiderosis 520
hyocalcemia 509
hyperkalemia 416
hypokalemia 415
iron deficiency 519
lead poisoning 552
metabolic acidosis 402
obesity 536
protein-energy malnutrition 535
Triacylglycerol synthesis 160
Tricarboxylic acid cycle 249f
Triglyceride 87f
Tripeptidases 198
Tropical splenomegaly syndrome 375
metabolism 497
Tubeless gastric analysis 357
Tuberculous meningitis 422
Tuberous xanthomata 342
Tubules handle substances differently 366f
Tumor
cell destruction 686
index substances 713
metastasis 722
necrosis factor 695
alpha 696
beta 696
receptor 746
of bile duct 349
of bladder 370
Turner syndrome 324
Types of
acid-base disturbances 398t
bilirubin 349
bond 547
calcium channels 503f
jaundice 349
lactic acidosis 400
metabolic pathways 99
radiation 734
rickets 472
transport
mechanisms 21t
systems 21f
tumor produced 708
Tyrosinemia 239
U
Uncouplers of oxidative phosphorylation 265
Units of chondroitin sulfate 80f
Unsaturated fatty acids 85
Upper part of jejunum 488
Uremic syndrome 370
Uridine diphosphate 142
Urinary
acidification 373
bilirubin 349
buffer 396
calculi 468
excretion 366
of porphyrins 276t
free cortisol 668
hydroxyproline excretion 510
osmolality 373
urobilinogen 350
Urocanic aciduria 244
Urogenic proteinuria 372
Uronic acid 74
Use of radioisotope tracers 98
V
Van Der Waals forces 6
Vascular
cell adhesion molecule 746
diseases 328
endothelial growth factor 746
occlusion in sickle cell anemia 291f
Ventromedial nucleus 660
Verner-Morrison syndrome 681
Vibrio cholerae 653
Vinyl phenols 553
Vitamin
deficiency 468
B6 deficiency 240
deficiency 244
and bone 505
and innate immunity 472
and metabolic syndrome 473
and renal tubules 505
resistant rickets 21
cycle 475f
deficiency 352
dependent carboxylase 475
reductase 475f
Volatile acids 393
Voltage dependent anion channel 268
Vomiting 412
W
Wald's visual cycle 465f
Water soluble vitamins 463
Watson-Crick model of DNA structure 575
Weak and strong acids 391
Wernick's disease 141
Westergard multirule chart 444
Wet beriberi 478
Whipple's disease 242
White adipose tissue 162
WHO classification of malnutrition 535t
Williams-Beuren syndrome 723
Wobbling phenomenon 599
Wolman's disease 344