This chapter provides detail description of Fungal infections. Chapter has 5 well illustrated diagrams and pictures. Fungal infections, classification of fungi, pathogenesis of fungal infection, opportunistic fungi, meningitis, meningoencephalitis, brain abscesses/infarction/haemorrhages, stroke syndromes, spinal syndromes, evidence of fungal infection in central nervous system, treatment of fungal infection, poor prognosis factors, cryptococcosis, aspergillosis, north American blastomycosis, nocardiosis, coccidioidomycosis, candidiasis, mucormycosis, pseudo allescheriaboydii and meningeal syndrome are given in detail. 166 references are included at the end of the chapter to facilitate further reading.