This chapter has well written text and 9 well illustrated diagrams showing congenital malformations of cerebrum. Pathogenesis of development of cerebrum, commissural agenesis, schizencephaly, microcephaly, megalocephaly, holoprocencephaly, pachygyria, focal cortical dysplasia are described in detail. All conditions are illustrated with the help of functional imaging technique with radiographs. A table is added to summarise different causes of congenital malformations. Management and prognosis of congenital malformations are described at the end of the chapter. 82 references are given for further reading to conclude this chapter.