This chapter provides detail description of Spondylolisthesis. Chapter has 18 well illustrated diagrams and pictures. Spondylolisthesis, classification and aetiology of spondylolisthesis, isthmic spondylolisthesis, factors disposing to degenerative spondylolisthesis (DSO), degenerative spondylolisthesis, dysplastic spondylolisthesis, traumatic and pathological spondylolisthesis, grading of severity of vertebral slip, clinical features and their basis of spondylolysis and spondylolisthesis, investigations of spondylolisthesis, management of spondylolisthesis and surgical management of spondylolisthesis are described in detail. 7 tables are included to highlight Wiltse-Newman-MacNab classification of spondylolisthesis, factors predisposing to DSO, decompression alone strategy alone in DSO, fusion surgery in DSO and reason for using instrument in lumbar fusion. 69 references are included at the end of the chapter to facilitate further reading.