Second Edition
Editor Sandeep Saxena MS MAMS
Member, National Academy of Medical Sciences, India
DAAD Visiting Professor, University of Bonn, Bonn, Germany
Visiting Professor, UNC-Chapel Hill, Chapel Hill, USA
Fellow, Barnes Retina Institute and Anheuser-Busch Eye Institute, St Louis, USA
Fellow, New York-Presbyterian Hospital, New York, USA
Professor, Department of Ophthalmology CSM Medical University (Erstwhile, King George's Medical University) Lucknow, Uttar Pradesh,India
Jitendar P Vij
Jaypee Brothers Medical Publishers (P) Ltd
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Clinical Ophthalmology: Medical and Surgical Approach
© 2010, Sandeep Saxena
All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the editor and the publisher.
First Edition: 2003
Second Edition: 2011
9789350250044
Typeset at JPBMP typesetting unit
Printed at
My parents Dr R C Saxena and Mrs Madhu Saxena
&
My family Sangeeta, Shreeya and Aishwarya
7Contributors
- Leonardo Akaishi, md
- Director
- Hospital Oftalmólogico de Brasília
- Modulo G, Brazil
- Harmohina Bagga, md
- Formerly, Glaucoma Fellow
- VST Center for Glaucoma Care
- LV Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Samar K Basak, md, dnb
- Disha Eye Hospital and Research Center
- Barrackpore, Kolkata, West Bengal, India
- M Baskaran, do, dnb
- Consultant, Glaucoma Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Arnab Biswas, doms, frcs
- Consultant Oculoplastic and Orbital Surgeon
- Alo Eye Care
- Kolkata, West Bengal, India
- Jyotirmay Biswas, ms, fams
- Head, Uveitis Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Gagandeep S Brar, ms
- Formerly, Assistant Professor
- Advanced Eye Center
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- Arindam Chakravarti, ms
- Vitreoretinal Consultant
- Aditya Jyot Eye Hospital Private Limited
- Mumbai, Maharashtra, India
- Sunita Chaurasia, ms
- Consultant, Cornea Service
- LV Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Tanuj Dada, md
- Associate Professor
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Taraprasad Das, md, frcs
- Director
- Head, Retina Service
- LV Prasad Eye Institute
- Bhubaneswar, Orissa, India
- Sachi Devi, ms
- Glaucoma Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Kumar Doctor, ms
- Doctor Eye Institute
- Mumbai, Maharashtra, India
- Satpal Garg, md
- Professor
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Ronnie George, ms, do, dnb
- Consultant, Glaucoma Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Lingam Gopal, ms, dnb, frcs, fams
- Director of Research
- Medical and Vision Research Foundation
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Amod Gupta, ms, fams
- Professor and Head
- Advanced Eye Center
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- Preeti Gupta, ms
- Department of Ophthalmology
- CSM Medical University
- Lucknow, Uttar Pradesh, India
- Vishali Gupta, ms
- Associate Professor
- Advanced Eye Center
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- Albrecht Hennig, md
- Program Director
- Sagarmatha Choudhary Eye Hospital
- Lahan, Nepal
- Santosh G Honavar, md, facs
- Director, Ophthalmic Plastic Surgery
- Orbital Diseases and Ocular Oncology
- LV Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Chanda Hingorani, ms
- Doctor Eye Institute
- Mumbai, Maharashtra, India
- Subhadra Jalali, ms
- Head, Smt Kanuri Santhamma Retina
- Vitreous Center
- LV Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Apjit Kaur, ms
- Professor
- Department of Ophthalmology
- CSM Medical University
- Lucknow, Uttar Pradesh, India
- Sushmita Kaushik, ms
- Assistant Professor
- Advanced Eye Center
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- Mohit Khattri, ms
- Department of Ophthalmology
- CSM Medical University
- Lucknow, Uttar Pradesh, India
- Atul Kumar, md, fams
- Professor
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Poonam Kishore, ms
- Professor
- Department of Ophthalmology
- CSM Medical University
- Lucknow, Uttar Pradesh, India
- Ajit B Majji, md
- Consultant, Smt Kanuri Santhamma Retina Vitreous Center
- LV Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- J Manju, b opt
- Electrodiagnostic Department
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Kanwar Mohan, ms
- Formerly, Associate Professor
- Department of Ophthalmology
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- R Muralidhar, ms
- Consultant, Cornea Service
- LV Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Krishna R Murthy, ms
- Vitreoretinal Department
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Praveen R Murthy, ms, dnb
- Vitreoretinal Department
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Milind N Naik, ms
- Consultant, Division of Ophthalmic Plastic Surgery, Facial Aesthetic Surgery, Orbit and Ocular Oncology
- L V Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Arun Narayanaswamy, dnb
- Consultant, Glaucoma Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- S Natarajan, do
- Chairman and Managing Director
- Aditya Jyot Eye Hospital Private Limited
- Mumbai, Maharashtra, India
- Aditya Neog, do, dnb
- Glaucoma Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Canrobert Oliveira, md
- Director, Refractive Surgery
- Hospital Oftalmólogico de Brasília
- Modulo G, Brazil
- Surinder S Pandav, ms
- Additional Professor
- Advanced Eye Center
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- R Priya, m phil (opt)
- Electrodiagnotic Department
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Jagat Ram, ms
- Professor
- Advanced Eye Center
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- Kavita Rao, ms
- Consultant
- Aditya Jyot Eye Hospital Private Limited
- Mumbai, Maharashtra, India
- Srinivas K Rao do, dnb, frcs
- Formerly, Consultant Cornea Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Ritika Sachdev, ms
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Chinmaya Sahu, ms
- Uveitis Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Virender Sangwan, ms
- Associate Director
- Director, Cornea and Uveitis Services
- L V Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Puneet Saxena ms, mba
- Director, Industry Strategy
- JDA
- Dallas, USA
- Sandeep Saxena ms mams
- Professor
- Department of Ophthalmology
- CSM Medical University
- Lucknow, Uttar Pradesh, India
- G Chandra Sekhar, md
- Director
- Head, VST Center for Glaucoma Care
- LV Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Parveen Sen, ms
- Consultant, Vitreoretinal Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Mahesh P Shanmugam, do, dnb, phd, frcs
- Formerly, Consultant Vitreoretinal Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Namrata Sharma, md
- Associate Professor
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Rashmi Shetty, mbbs, frsh
- Consultant Cosmetic Physician
- Revival Clinic
- Mumbai, Maharashtra, India
- Kirti Singh md, dnb, frcs
- Professor, Glaucoma Division
- Guru Nanak Eye Center
- Maulana Azad Medical College
- New Delhi, India
- Vinita Singh, ms
- Professor and Head
- Department of Ophthalmology
- CSM Medical University
- Lucknow, Uttar Pradesh, India
- Rajesh Sinha, md, frcs
- Assistant Professor
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Subijoy Sinha, md
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Late G Sitalakshmi, do, frcs
- Consultant, Cornea Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Parul Sony, md
- Formerly, Senior Research Associate
- Dr Rajendra Prasad Center for
- Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- S Sudharshan, do
- Consultant, Uveitis Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
- Radhika Tandon, md
- Professor
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Mukesh Taneja, ms
- Consultant, Cornea Service
- L V Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Manoj K Tangri, ms
- Senior Partner Manager
- Hewlett-Packard Company
- Fort-Collins, USA
- Hem K Tewari, md
- Formerly, Professor and Chief Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Jeewan S Titiyal, md
- Professor
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Vasumathy Vedantham, ms, frcs
- Former Retina Fellow
- Smt Kanuri Santhamma
- Retina Vitreous Center
- L V Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Geeta K Vemuganti, md
- Ophthalmic Pathology Division
- L V Prasad Eye Institute
- Hyderabad, Andhra Pradesh, India
- Pradeep Venkatesh, md
- Associate Professor
- Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Lalit Verma, md
- Formerly, Additional Professor Dr Rajendra Prasad Center for Ophthalmic Sciences
- All India Institute of Medical Sciences
- New Delhi, India
- Lingam Vijaya, ms
- Head, Glaucoma Service
- Sankara Nethralaya
- Chennai, Tamil Nadu, India
The pace of change in ophthalmology is rapid and requires us to constantly update our skills and knowledge. We are subspecialized to a degree that demands that we must stay in close communication with our colleagues to be able to follow the advances occurring in the separate subdivisions of our specialty. In this challenging intellectual environment, a text bringing together respected authors from multiple disciplines is particularly welcome, and Dr Saxena has accomplished this task with great success. Twenty-one chapters cover new concepts and technological advances in the diagnosis and management of common ophthalmic disorders. Several chapters deal with advances in lens surgery, and several authorities cover new concepts in retinal disease including macular and submacular surgery. Modern concepts in corneal disease, glaucoma, oculoplastics, ocular oncology, infectious and inflammatory diseases, strabismus, trauma, and optic nerve disorders are each presented by experts in ophthalmology. As ophthalmology has become more complex, we are driven to establish higher standards of scientific proof for our treatments and simultaneously to run our practices with greater efficiency to be able to bring the best of high technology to bear on our patients' problems while being mindful of cost. Thus, I was particularly pleased to see practice management and clinicial trials covered in this text. Dr Saxena is an extraordinarily gifted and energetic physician and academician who, along with his fellow authors, has produced a book, which is an important contribution to contemporary ophthalmic education. Readers will benefit greatly from this accomplishment.
Travis A Meredith md
Sterling A Barrett Distinguished Professor
Chairman, Department of Ophthalmology
University of North Carolina
Chapel Hill, USA
13Preface to the Second Edition
Ophthalmology is a continuously advancing field. As new technologies are being introduced at a rapid pace, the ophthalmologist must learn their intricacies as one begins to apply them to the treatment of ocular diseases. The adoption of new technology, in turn, brings with it the need to learn new skills and develop new treatment algorithms. Old concepts change and new ideas are plentiful. Everything is difficult before it becomes easy.
Clinical Ophthalmology: Medical and Surgical Approach is being launched as the second edition of Clinical Practice in Ophthalmology. This text attempts to update the state-of-the-art ophthalmology in a lucid, authoritative and well-illustrated manner. Ten sections encompassing forty-four chapters provide a new insight into the subject.
In this challenging intellectual environment Clinical Ophthalmology: Medical and Surgical Approach brings together a distinguished group of seventy-one experts and provides a comprehensive text combined with integrated visual reference, in the form of black and white and colored figures. The value of this book lays in the quality and expertise of the text chapter contributors. This book is intended for the experienced ophthalmologists, postgraduates as well as those in training. It is hoped that this book will be sufficiently comprehensive to aid the ophthalmologist in making diagnosis of common ophthalmic conditions as well as in performing competent surgeries. This pragmatic book provides an understanding of ophthalmology, important to the everyday practice. I hope this book will find a meaningful and valued place in the libraries of ophthalmologists, today and in future.
Sandeep Saxena
15Preface to the First Edition
With the evolution of new diagnostic and therapeutic modalities, the ophthalmologist has become more involved in decision-making for patients. The challenge facing the ophthalmologist lies in maintaining an up-to-date practical knowledge. This thirst for knowledge is typical of those who are fascinated by the subject, but is also true of those who develop a great understanding of the subject.
Clinical Practice in Ophthalmology, a multi-authored text, was conceptualized in New York, USA. The publisher and the contributing authors were contacted on Internet to lay the groundwork. This book summarizes the present knowledge of clinical ophthalmology and practice management. The value of this book lies in the quality and expertise of the authors of the selected subjects. The authors have presented the material to provide the reader with a quick, but comprehensive review of the major ophthalmological issues. This pragmatic book provides an understanding of diseases so important to the everyday practice of ophthalmology. I hope this book will find a meaningful and valued place in the libraries of ophthalmologists, today and in future.
This book would not have been possible without the guidance of my mentors, cooperation of my family and help of Dr SK Bhasker.
Sandeep Saxena