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Chapter-08 Liver Donation after Brain Death and Cardiac Death

BOOK TITLE: Liver Transplantation

Author
1. K Dilip Chakravarty
2. Lee WC
3. Jan YY
4. Lee Po-Huang
ISBN
9788184487701
DOI
10.5005/jp/books/10445_8
Edition
1/e
Publishing Year
2010
Pages
9
Author Affiliations
1. Chang Gung Memorial Hospital (Linkou), Taipei, Taiwan (ROC)
2. Chang Gung Transplantation Institute (Linkou), Chang Gung University, Taipei, Taiwan (ROC)
3. Chang Gung Memorial Hospital (Linkou), Chang Gung University, Taipei, Taiwan (ROC)
4. National Taiwan University Hospital, Taipei, Taiwan (ROC)
Chapter keywords

Abstract

Introduction of direct brain stem testing in the 1970s’ changed the emphasis to utilising organs from so-called donation after brain death (DBD) or heart beating donors. Initially heart beating donors were used for organ donation. Later the concept of live related donor and non-heart beating donor started due to shortage of donor organs from brain dead patients, increased demand of the long waiting list, improvements in diagnosis and management of severe brain injuries and reduction in numbers of severe head injuries . Unlike DBD donors, use of these livers from non-heart beating donors is very selective and consideration was taken into the donor age, hemodynamic stability before withdrawal of support, total warm ischemic time and appearance of the liver intraoperatively. Warm ischemic time in NHBD is defined as the time between the cardiac arrest and cannulation and should be <30 minutes. Proper selection of the donor is important to achieve good results.

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