Aim: This study evaluated the influence of light emitting diode (LED) illumination bleaching technique on color stability of various computer-aided design–computer-aided manufacturing (CAD–CAM) of ceramic materials. Materials and methods: A total of 20 disk-shaped samples (width × length × thickness = 10 mm × 15 mm × 2 mm) were prepared from each of the ceramic materials for CAD–CAM including Lava™ Ultimate (LV), Vita Enamic® (En), IPS e.max® CAD (Me), inCoris® TZI (IC), and Prettau® zirconia (Pr). The samples from each type of ceramic were randomly divided into two groups based upon different bleaching techniques using 35% hydrogen peroxide with and without LED illumination. Colorimetric evaluation was determined using spectrophotometer for color differences. Results: The color difference (ΔE) upon bleaching, either without or with LED illumination [mean ± standard deviation (SD)], for each type of ceramic was 0.34 ± 0.21, 0.54 ± 0.41 for LV groups; 5.59 ± 1.35, 5.81 ± 1.45 for En groups, 4.60 ± 1.80, 6.92 ± 1.42 for Me groups, 3.43 ± 1.04, 4.14 ± 0.72 for IC groups, and 6.61 ± 0.80, 7.03 ± 0.64 for Pr groups respectively. The differences in color changes were indicated upon bleaching procedure in different degrees for the different ceramic materials. The analysis of variance (ANOVA) indicated significant differences of color change due to the effect of bleaching technique on the ceramic material (p < 0.05). Conclusion: Bleaching can affect the color stability of dental ceramics for CAD–CAM. Using 35% hydrogen peroxide bleaching agent with LED illumination caused more color alteration of dental ceramics than without LED illumination. Clinical significance: B leaching a ffects c olor o f c eramic materials. Clinicians should be careful in the protection of the existing restoration.