Twin-to-twin Transfusion Syndrome: An Overview

JOURNAL TITLE: World Journal of Anemia

Author
1. Richa Saxena
2. Kanav Midha
ISSN
DOI
10.5005/jp-journals-10065-0041
Volume
2
Issue
3and4
Publishing Year
2018
Pages
7
  • Article keywords
    Dizygotic, Fetus, Gestation, Monozygotic, Twin–twin transfusion syndrome

    Abstract

    Twin-to-twin transfusion syndrome (TTTS) is a severe problem that affects 10–15% of monochorionic (MC) multiple pregnancies. Connecting placental vessels on chorionic plate between donor and recipient twin is accountable for inequality of blood flow. There is an indication for the superiority of fetoscopic laser ablation over serial amnioreductions regarding survival and neurological outcome for stages II–IV TTTS. However, the optimal management of stage I is still debated. In this review, we discuss the basics of twin gestation, optimal management, pathophysiology, long-term neurodevelopmental outcome, and future aspects of TTTS.

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