Fanconi Anemia

JOURNAL TITLE: World Journal of Anemia

Author
1. Sudha Chamoli
2. Richa Saxena
3. Mampi Debnath
ISSN
DOI
10.5005/jp-journals-10065-0031
Volume
2
Issue
2
Publishing Year
2018
Pages
6
Author Affiliations
    1. Jaypee Brothers Medical Publishers, New Delhi, India
  • Article keywords
    Acute myeloid leukemia, Fanconi anemia, Diepoxybutane, Human papillomavirus, Hematopoietic stem cell transplantation, Mitomycin C, Myelodysplastic syndrome

    Abstract

    Fanconi anemia (FA) is an infrequently occurring autosomal recessive disorder that is genetically and phenotypically heterogeneous. The main features include myriad of congenital malformations, progressive pancytopenia, and predisposition to both hematologic malignancies as well as solid tumors. Here, in this article, topics such as the association of FA with other syndromes, FA-associated genes and cancer susceptibility, researches in FA, gynecological concerns, management, and diagnostic strategies have been discussed elaborately.

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