Blastocyst Culture and Embryo Transfer on Day 5 following Fertilization is a Viable Strategy for Acceptable Results in in vitro Fertilization: Intracytoplasmic Sperm Injection Program

JOURNAL TITLE: Journal of South Asian Federation of Obstetrics and Gynaecology

Author
ISSN
0974-8938
DOI
10.5005/jp-journals-10006-1575
Volume
10
Issue
2
Publishing Year
2018
Pages
3
Article keywords
Blastocyst transfer, In vitro fertilization, Intracytoplasmic sperm injection

Abstract

Despite considerable advances in the field of in vitro fertilization (IVF), embryo implantation and pregnancy rates have plateaued globally. Thus, much of current research focus is on embryo and endometrial assessment. Day 3 embryo transfers (ETs) have been the standard of practice for long. However, development of blastocyst culture media has led to recent switch toward blastocyst transfers, although this is associated with greater technical skill and know-how in order to optimize the culture process. We analyzed our blastocyst transfer results to see whether this strategy appeared to be a viable intervention in terms of acceptable pregnancy outcome. Our study found a pregnancy rate of 37.5% with blastocyst transfers, with the complete absence of any multiple pregnancies. Thus, we feel blastocyst transfers represent a viable intervention in an IVF program to ensure acceptable pregnancy rates and simultaneously reduce the incidence of multiple births.

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