Background: Pregnant women are uniquely susceptible to severe illnesses with a viral infection, possibly due to the shift from cellular to humoral immunity during pregnancy and puerperium. The relationship between clinically evident polyhydramnios in coronavirus disease 2019 (COVID-19) infection and poor perinatal outcome has not been evaluated. Case description: We describe as case of 28-year-old pregnant female with mild systemic disease (ASA-II) having COVID-19 with moderate polyhydramnios underwent an emergency cesarean section under spinal anesthesia due to fetal distress. She had class II obesity, cough, and fever with moderate COVID-19. Conclusion: Since COVID-19 is a viral infection, it may have caused placental insult due to cytokine storm during the pregnancy and resulted in polyhydramnios.