Background: Mobile (M) learning is an emerging platform for students to learn through smartphones. The widespread use of smartphones on medical college campuses among the students and the faculty has now emerged as an interesting and immediate tool for acquiring knowledge. The smartphone can also become an efficient method in teaching and learning programs. Review results: Out of the 100 students who participated in the study, 83 of them liked the WhatsApp-based M-learning program (83%). Conclusion: This study found immediate acceptance of a new learning mode, that is, the M-learning WhatsApp mode, thus serving as an eye-opener that students are open to newer learning methods. Newer learning methods should be introduced in the curriculum. Academic significance: A large number of students used smartphones for communication, education, entertainment, navigation, and gaming purpose, so this method would help channelize the proper and effective use of the electronic gadget. Moreover, the WhatsApp application supports free voice and video calls so teachers and students can stay in touch, even outside the stipulated periods.