Sensitivity pattern of Salmonella serotypes from a tertiary care hospital of Punjab

JOURNAL TITLE: Journal of Gastrointestinal Infections

1. Rajoo S Chhina
2. Deepinder Kaur
3. Amarjeet Kaur
4. Pooja Suri
5. Rama Gupta
6. Kanwaldeep Singh
Publishing Year
Author Affiliations
    1. CSM Medical University (Erstwhile King George’s Medical University) Lucknow, India
    1. Department f Microbiology, Dayanand Medical College & Hospital, Ludhiana
    1. Department of Microbiology, Medanta - The Medicity, Gurgaon, Haryana
    1. Department of Microbiology, Dayanand Medical College & Hospital, Ludhiana, Punjab, India.
    1. Medicine Dayanand Medical College and Hospital, Ludhiana, Punjab, India
  • Article keywords
    Antimicrobial sensitivity, Enteric fever, Salmonella Paratyphi A, Salmonella Typhi


    Enteric fever is classically caused by S. Typhi & S. Paratyphi A, B & C and it is known to be endemic in India. For optimal patient care, precise information on antibiotic susceptibility pattern is required. Hence, this studywas undertaken to know the antimicrobial sensitivity profile of Salmonella serotypes isolated fromblood in a tertiary care hospital of Punjab. All the blood samples received from January 2010 – December 2011 were processed by automated blood culture systems (BACTEC 9240/Bac T-Alert 3D). Identification and antimicrobial susceptibility pattern of Salmonella strains was studied by automated identification system (Micro Scan Walk-Away/ VITEK 2). Out of a total of 35854 blood samples, 5234 (14.6%) samples were found to be positive for bacterial growth, of which 363 (6.93%) were Salmonella spp. Of these, 281 (77.4%) were S. Typhi and 82 (22.6%) were S. Paratyphi A. Only 2 (0.7%) isolates of S. Typhi were found resistant to ampicillin and trimethoprim-sulfamethoxazole, and 5 (1.8%) were resistant to ciprofloxacin & levofloxacin. All the S. Typhi isolates were sensitive to 3rd generation cephalosporins. S. Paratyphi A isolateswere sensitive (100%) to all the drugs, except trimethoprim-sulphamethoxazole (97.6%) & ceftriaxone (98.8%). Though multi drug resistant Salmonella are being reported fromvarious parts of India, in our region the Salmonella isolates are still susceptible to the commonly used drugs.

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