Guidewires play a significant role in many medical specialties.1 They were initially developed for vascular procedures,2 but are also nowadays an essential tool in endourology. The knotting of the guidewire is a very rare complication and only a few cases have been reported until now. We report a case of spontaneous intraurethral knotting of guidewire on the Foley catheter during per urethral catheterization that led to retained Foley catheter with the guidewire. The balloon was punctured percutaneously with a needle under ultrasound guidance but due to knotting guidewire and Foley catheter, both are stuck in the urethra. A guidewire knot was found proximal to the balloon. The urethroscopy shows the knotting of the guidewire with a Foley catheter. Open urethrotomy done and both guidewire and Foley catheter removed.
