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Oral signs and symptoms most of the times indicate a local disease and can be treated with dental treatment; however, sometimes it can be an indication of any underlying severe disease. Acute myeloid leukemia is one such grave hematological malignancy with a very short lifespan if undiagnosed and left untreated, which shows oral signs as the first clinical manifestations of the disease. This is a case report where oral findings lead to diagnosis of acute myeloid leukemia in a 55-year-old female.
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