A Rare Case of Transitional Cell Carcinoma of Ovary: Case Report and Review of Literature

JOURNAL TITLE: The Journal of Medical Sciences

Author
1. PS Sharmila
2. BM Rupakala
3. TS Anisha
4. Ajay K Sahu
5. Jyothi A Raj
6. M Gautham
ISSN
2321-354X
DOI
10.5005/jp-journals-10045-0063
Volume
3
Issue
3
Publishing Year
2017
Pages
4
Author Affiliations
    1. Department of Pathology, RajaRajeswari Medical College and Hospital, Bengaluru, Karnataka, India
    1. Department of Obstetrics and Gynecology, RajaRajeswari Medical College and Hospital, Bengaluru, Karnataka, India
    1. Department of Pathology, Raja Rajeswari Medical College & Hospital, Bengaluru, Karnataka, India
    1. Department of Pathology, Raja Rajeswari Medical College & Hospital, Bengaluru, Karnataka, India
    1. Department of Pathology, Raja Rajeswari Medical College & Hospital, Bengaluru, Karnataka, India
    1. Department of Radiology, Raja Rajeswari Medical College & Hospital, Bengaluru, Karnataka, India
  • Article keywords

    Abstract

    Introduction: Transitional cell carcinoma (TCC) of the ovary is a rare and recently recognized variant of epithelial ovarian cancer. It has been described as primary ovarian carcinoma with definite urothelial features, without benign, metaplastic, and/or proliferating Brenner tumor (BT) identified. Case report: A 60-year-old lady presented with low back pain, growing abdominal mass, and loss of weight since 15 days. Magnetic resonance imaging (MRI) of abdomen showed a large ill-defined heterogeneous lesion with solid and cystic components. Beta human chorionic gonadotropin (β-hCG) and carcinoembryonic antigen (CEA) levels were raised. Surgery was performed and primary TCC of ovary was reported on histopathology. Conclusion: Recognition of such tumors is important because of their rarity, favorable response to chemotherapy, and improved patient survival.

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