Management of Drug-induced Weight Gain in Persons Receiving Psychotropic Drugs

JOURNAL TITLE: Indian Journal of Private Psychiatry

Author
1. Samir K Praharaj
2. Vikas Menon
ISSN
2319-5363
DOI
10.5005/jp-journals-10067-0071
Volume
15
Issue
1
Publishing Year
2021
Pages
7
Author Affiliations
    1. Center for Sight, New Delhi, India
    2. Center for Sight Eye Hospital, New Delhi, India
    3. Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India
    1. Department of Psychiatry, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India
  • Article keywords
    Metabolic syndrome, Obesity, Psychotropic drugs, Severe mental illness, Weight gain

    Abstract

    Weight gain is common in patients with severe mental illness and contributes to cardiovascular risk. Medications, such as antipsychotics, antidepressants, and mood stabilizers, are commonly associated with weight gain. In addition, antidiabetic drugs (insulin, sulfonylureas, and thiazolidinediones), antihypertensives (beta-blockers), and corticosteroids, which are commonly used to treat comorbid medical conditions, contribute to weight gain. In clinical practice, simple measures, such as body weight, body mass index, and waist circumference, can be used to monitor the metabolic risk of psychotropic drugs. Lifestyle modifications, including dietary advice and exercise, help in preventing weight gain. The clinician can choose relatively weight-neutral drugs for the treatment of psychiatric disorders. For the patients having weight gain with psychotropic drugs, several nonpharmacological and pharmacological management strategies are available.

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