Bone has a unique capacity to regenerate itself completely. The major limiting factor is maintenance of space for bone formation. Bone graft materials have been used to facilitate bone formation within a space by occupying the space and allowing subsequent bone growth. Osseous grafting has been shown to be clinically successful in the management of human periodontal defects. Autogenous bone graft is considered as the gold standard for bone regeneration due to its unique properties of osteogenesis, osteoconduction, and osteoinduction. For more predictable regeneration of bone, autografts can be combined with platelet concentrates. This clinical case letter reports a case of Siebert's class I ridge defect which was treated with the staged guided bone regeneration (GBR) approach using autogenous block graft and platelet-rich fibrin (PRF).