Pregnancy-associated New-onset Progressive Keratoconus with Horizontally Aligned Vogt's Striae in a 36-year-old Female

JOURNAL TITLE: International Journal of Keratoconus and Ectatic Corneal Diseases

1. James McKelvie
2. Daniel AR Scott
3. Graham Wilson
Publishing Year
Author Affiliations
    1. Department of Ophthalmology, Gisborne Hospital, Hauora Tairāwhiti, Gisborne, New Zealand
    1. Department of Ophthalmology, Gisborne Hospital, Hauora Tairāwhiti, Gisborne, New Zealand; Mātai Lab, Gisborne, New Zealand
    1. Department of Ophthalmology, The University of Auckland, Auckland, New Zealand
  • Article keywords
    Horizontal Vogt\'s striae, Keratoconus, Pregnancy-associated progression


    Aim: The aim of the study is to report a case of pregnancy-associated progressive keratoconus with atypical horizontally aligned Vogt\'s striae. Background: Hormonal changes during pregnancy have been proposed as a risk factor for progressive keratoconus. There have been only a few cases of progressive keratoconus diagnosed with progression after pregnancy, without either an existing disease or an attributable cause. Case description: A 36-year-old New Zealand European woman presented with progressive myopic astigmatism following her first pregnancy. Stigmata of keratoconus were present on clinical examination and included horizontally aligned Vogt\'s striae. Tomography measurements confirmed the diagnosis with characteristic inferior corneal steepening and ectasia bilaterally. The patient was advised to abstain from eye rubbing, commenced topical olopatadine, and underwent corneal collagen cross-linking following delivery to prevent further keratoconus progression. Conclusion: Pregnancy-associated progressive keratoconus in a 36-year-old woman was documented after the pregnancy. Clinical significance: Atypical presentation features that include horizontally aligned Vogt\'s striae, advanced age at diagnosis, and rapid pregnancy-associated progression in a previously stable patient.

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