Treatment Intensification in the ‘High-risk’ Individual

JOURNAL TITLE: International Journal of Head and Neck Surgery

Author
1. Prathamesh S Pai
ISSN
0975-7899
DOI
10.5005/jp-journals-10001-1016
Volume
1
Issue
2
Publishing Year
2010
Pages
4
Author Affiliations
    1. Department of Head and Neck Surgical Oncology, Tata Memorial Hospital, Mumbai Maharashtra, India
  • Article keywords

    Abstract

    The high-risk individual merits treatment intensification. However, there are concerns with CERT. More supportive care is necessary as toxicity is higher. Treatment related death is a reality. Hence before we set out to prescribe concurrent chemoradiation we would need to stratify them according to the risk factors, their performance status and bear in mind the costs involved in intensive support during treatment.

    Apart from chemoradiation we need to explore emerging treatment strategies such as fractionated radiation therapy, and targeted therapies such as epidermal growth factor receptor blockade which might offer better if not similar results but with lesser toxicity.

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