Background: Thyroidectomy is a widely performed surgical procedure globally with respect to the benign and malignant disorder of thyroid gland. Total thyroidectomy, one of the most commonly performed procedures in India, carries inherent risks, predominantly hypocalcemia, voice disturbances, and other complications. Our study explores the role of steroids in potentially reducing these complications. Aim: To evaluate the effectiveness of prophylactic steroids in preventing hypocalcemia in patients undergoing total thyroidectomy. Additionally, the study examines other parameters, including pain and voice changes. Method: This randomized controlled double-blind trial included two arms: A placebo group and a steroid group, comparing outcomes between the two groups. Results and conclusion: Our study demonstrated a noticeable difference, with fewer patients in the steroid group developing hypocalcemia; however, the results were not statistically significant. Importantly, no complications due to steroid use were observed. We noted statistically significant benefits in the steroid group regarding reduced postoperative voice dysfunction and pain. A study with a larger sample size is needed to draw more definitive conclusions.