Inadequate and inappropriate handling of health care waste may have serious public health consequences and a significant impact on the environment. The Ministry of Environment and Forests (MoEF) has notified the new Biomedical Waste Management rules (BMWM Rules, 2016) on March 28, 2016, under the Environment (protection) Act, 1986, to replace the earlier rules (1998) and the amendments thereof. These rules shall apply to all persons who generate, collect, receive, store, transport, treat, dispose, or handle biomedical waste in any form. Sufficient financial and trained human resources, proper monitoring and control of waste disposal are some challenges for the management of biomedical waste. Thus, appropriate management of health care waste is a crucial component of environmental health protection, and it should become an integral feature of health care services. If we want to protect our environment and health of the community, we must sensitize ourselves to this important issue not only in the interest of health managers but also in the interest of community. How to cite this article Singh H, Joshi HS, Singh A, Katyal R, Singh R. Biomedical Waste Management Rules, 2016: A Brief Review. Int J Adv Integ Med Sci 2017;2(4):201-204.