Cirrhotic Cardiomyopathy in Bangladeshi Patients: A Pilot Study

JOURNAL TITLE: Euroasian journal of hepato-gastroenterology

Author
1. Ranjit Kumar Banik
2. Shasanka Kumar Saha
3. Madhusudan Saha
4. Khondoker Asaduzzaman
ISSN
2231-5047
DOI
10.5005/jp-journals-10018-1061
Volume
3
Issue
1
Publishing Year
0
Pages
4
Author Affiliations
    1. Department of Gastroenterology, North East Medical College, Sylhet, Bangladesh
    1. Department of Gastroenterology, Sir Salimullah Medical College, Dhaka, Bangladesh
    1. Department of Gastroenterology, Sir Salimullah Medical College, Mitford Hospital, Dhaka, Bangladesh
    1. Department of Gastroenterology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh
  • Article keywords

    Abstract

    Background: Cirrhotic cardiomyopathy is reported to be a major cause of mortality and morbidity in liver transplant recipient. It might be an emerging issue as liver transplantation has been started in Bangladesh. Materials and methods: Forty-four cirrhotic patients of varying etiology and 44 healthy volunteers were enrolled as cases and controls, respectively. Hepatic functional status was assessed by clinical examination and biochemical tests. Transthoracic echocardiography was done in both the groups. Results: Deceleration time of cirrhotic patients was significantly prolonged irrespective of etiology in comparison to controls indicating diastolic dysfunction. Left ventricular systolic diameter was also larger (significant statistically) in cirrhotic patients. Other echocardiographic parameters like E/A ratio, EF, left ventricle (LV) wall thickness, interventricular septal thickness and LV diastolic diameter showed no significant difference. Cardiac dysfunction does not depend on severity of hepatic dysfunction. Conclusion: Cirrhotic patients irrespective of cause show diastolic dysfunction. Cardiac dysfunction did not correlate the severity of hepatic dysfunction.

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