Lucio Phenomenon and APLA in Hansen's Disease: A Rare Phenomenon

JOURNAL TITLE: Bengal Physician Journal

Author
1. Jayanta Sharma
2. Parthajit Das
3. Sudipto Chakroborty
4. Kisholoy Karan
ISSN
DOI
10.5005/jp-journals-10070-7088
Volume
9
Issue
2
Publishing Year
2022
Pages
4
Author Affiliations
    1. Geriatric and Internal Medicine, Apollo Multispeciality Hospitals, Kolkata, West Bengal, India
    1. Department of Internal Medicine, Apollo Multispeciality Hospitals, Kolkata, West Bengal, India
    1. Department of Neurology, Apollo Multispeciality Hospitals, Kolkata, West Bengal, India
    1. Department of Rheumatology, Apollo Multispeciality Hospitals, Kolkata, West Bengal, India
    2. Apollo Gleneagles Hospital, Kolkata, West Bengal, India
  • Article keywords
    Lepromatous leprosy, Lucio phenomenon, Purpuric macules, Systemic lupus erythematosus

    Abstract

    Lucio phenomenon (LP) is a rare reactional state seen in cases of diffuse lepromatous leprosy. Lucio leprosy is a pure, primitive, and diffuse form of lepromatous leprosy. It is observed almost exclusively in Mexico and Central America and is considered a globally restricted phenomenon. However, isolated cases are being reported worldwide. Patients with Lucio leprosy often present with manifestations of LP, which includes purpuric macules with multiple and extensive areas of ulceration with bizarre-patterned, angulated borders mainly affecting the extremities. Lucio phenomenon is difficult to recognize, especially in nonendemic countries, which can lead to a delay in its diagnosis and management. We report a case of LP due to its occurrence in the classical form of lepromatous leprosy and rarity in Eastern India.

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