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Inhaled Glucocorticoids in Rhinosinusitis: A Few Pharmacological Aspects, We Must Know

JOURNAL TITLE: Clinical Rhinology

Author

1. JS Thakur
2. NK Mohindroo
3. DR Sharma
4. Anamika Thakur

ISSN

0974-4630

DOI

10.5005/jp-journals-10013-1046

Volume

Issue

Publishing Year

2010

Pages

Author Affiliations

Department of ENT and Head and Neck Surgery, IG Medical College, Shimla, Himachal Pradesh, India

Department of ENT and Head and Neck Surgery, IG Medical College, Shimla, Himachal Pradesh, India

Department of ENT and Head and Neck Surgery, IG Medical College, Shimla, Himachal Pradesh, India

Department of Pharmacology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

Article keywords

Atopy, Inflammation, Fluticasone, Beclomethasone, Ciclesonide, Flunisolide, Budesonide

Abstract

Abstract

Inhaled glucocorticoids are very effective for the management of seasonal and perennial allergic rhinitis. Various glucocorticoids are available for inhalation therapy with varying affinity for the receptors. Inhaled glucocorticoids have very low incidence of systemic side effects at the usual therapeutic doses. In this review we have discussed the pharmacokinetics, pharmacodynamics and adverse effects profile of the commonly available inhaled glucocorticoids.