Microbiome is used to refer to the collection of genomes of microbes in a particular ecosystem whereas; microbiota is used to refer to the collection of organisms. Hospital microbiota and the invisible world of microbes called hospital microbiome. Of course, not all microbes are bad and most are benign or even beneficial; in some cases, may help protect patients against infections. Each new patient brings their own microbiome, which they shed on the hospital bed, the television remote and anything else they touch. Each nurse, doctor and visitor that enters the room drops microbes too. The tiny organisms also circulate through ventilation systems and travel through the air. The elimination of these commensal microbes reduces competition, potentially making hospitals friendlier toward pathogenic species.