Neurosurgical procedures for pain can be nonspecific or specific. The former are not specifically designed to address pain, although the improvement of pain is one of the surgical goals. Nonspecific procedures include nerve root decompressions by laminectomy, hemilaminectomy, or foraminotomy, releasing peripheral nerve entrapments, stabilization of an unstable spine, and correcting major spine deformities with instrumentation. Specific procedures are exclusively designed to address intractable pain and include destructive procedures and central electrical stimulations. Indications for specific procedures are two-fold following as cancer pain and chronic nonmalignant pain.