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Chapter-15 Antiemetics

BOOK TITLE: Nursing Drug Dosages and their Calculations

Author
1. Chattri GL
ISBN
9789386261076
DOI
10.5005/jp/books/14225_16
Edition
1/e
Publishing Year
2018
Pages
6
Author Affiliations
1. Metro Multispeciality Hospital and Seth Mannulal Jagannath Hospital, Jabalpur, Madhya Pradesh, India, Mahakoshal Hospital, Seth Mannulal Jagannathdas Trust Hospital and Research Centre and Metro Hospital, Jabalpur, Madhya Pradesh, India
Chapter keywords
Antiemetic, 5-HT3 antagonist, phenothiazine, dolasetron, granisetron, ondansetron, chlorpromazine, prochlorperazine, metoclopramide

Abstract

Antiemetic drugs are prescribed to help with nausea and vomiting that are side effects of other drugs. This may include drugs for anesthesia used during surgeries or chemotherapy for cancer. Antiemetics include 5-HT3 antagonists, phenothiazines, and miscellaneous. 5-ht3 antagonists include dolasetron, granisetron, ondansetron, and palonosetron. These agents act by blocking the effects of serotonin at 5 HT3 receptor sites centrally as well as peripherally on vagal nerve terminals. Phenothiazines include chlorpromazine, prochlorperazine, and promethazine. Miscellaneous include dimenhydrinate, domperidone, meclizine, and metoclopramide. Uses, dosage, and side effects of all these drugs are also covered in this chapter.

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