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Chapter-74 Ovarian Transplant

BOOK TITLE: Principles and Practice of Assisted Reproductive Technology

Author
1. Mhatre Jyoti
2. Mhatre Pravin
ISBN
9789352705030
DOI
10.5005/jp/books/18020_75
Edition
2/e
Publishing Year
2019
Pages
11
Author Affiliations
1. Kedar Hospital, Mumbai, Maharashtra, India
2. Seth GS Medical College, Mumbai; N Wadia, Mumbai, Maharashtra, India; Mat. Hospital, Mumbai, Maharashtra, India, GS Medical College, KEM Hospital, N Wadia Hospital, Mumbai, Maharashtra, India, Seth GS Medical College, KEM and Wadia Hospital, Mumbai, Maharashtra, India
Chapter keywords
Ovarian transplant, animal experiment, human experiment, ovarian vasculature, orthotopic transplant, uterine fundus, government permission

Abstract

The ovary unlike kidney, liver, or heart is not a vital organ required for life sustenance and therefore not lifesaving in true sense of words, but definitely improves the quality of life and is life producing for the recipient. Sturgis and Castellanos in 1958 demonstrated the survival of human ovarian homograft in millipore chamber of six patients of Turner syndrome. Desaire transplanted the ovary in spleen in the patient having generalized cancer and were castrated. Holmer transplanted the ovarian tissue in gonadal agenetic patients. None of these attempts in human were successful. Theoretically, there are many indications for ovarian transplant; however, ethical considerations are more important in the decision-making. This chapter covers history of ovarian transplant, animal experiments, human experiments, indications for ovarian transplant, problems associated with ovarian transplant, ovarian vasculature, site of ovarian transplantation, etc.

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