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Chapter-68 Maternal and Fetal Outcomes Following ART

BOOK TITLE: Principles and Practice of Assisted Reproductive Technology

Author
1. Rao Kamini A
2. V Navya
3. Upadhyay Amit J
ISBN
9789352705030
DOI
10.5005/jp/books/18020_69
Edition
2/e
Publishing Year
2019
Pages
9
Author Affiliations
1. Bangalore Assisted Conception Centre, Bangalore, Milann Fertility Centre, Bangaluru, Karnataka, India, Milann—The Fertility Center, Bengaluru, Karnataka, India, Milann (A Unit of BACC Health care Private Limited), Bengaluru, Karnataka, India, Milann (A Unit of BACC Healthcare Pvt Ltd), Bengaluru, Karnataka, India, Milann (A Unit of BACC, Healthcare Pvt Ltd), Bengaluru, Karnataka, India, Milann Group of Fertility Centers, Bengaluru, Karnataka, India, Bengaluru, Karnataka, India, Bengaluru, Milann—The Fertility Center (A Unit of BACC Healthcare Pvt Ltd), Bengaluru, Karnataka, India, Milann—The Fertility Center (A Unit of BACC Health Care Pvt Ltd), Bengaluru, Karnataka, India, Bangalore Assisted Conception Centre, Bangalore, Karnataka, India, BACC Health Care Private Limited, Bengaluru, Karnataka, India, Bangalore Assisted Conception Center (BACC), Bengaluru, Karnataka, India, FOGSI-2001; Bangalore Assisted Conception Center (An ISO 9002 Organization), Karnataka, India, Bangalore Assisted, Conception Centr
2. Tirupati, Andhra Pradesh, India, Medicine Tirupati, Andhra Pradesh, India
3. Srijan—The Fertility Center and Women Care Hospital, Mumbai, Maharashtra, India, Chaturthi Hospitals LLP, Mumbai, Maharashtra, India
Chapter keywords
Assisted reproductive technique, multiple pregnancy, preterm delivery, low birth weight, perinatal mortality, chromosomal disorder, imprinting disorder, preimplantation genetic screening, blastocyst culture, assisted hatching, in vitro maturation

Abstract

This chapter deals with the discussion on maternal and fetal outcomes following assisted reproductive technique (ART). The ART technology involves any procedure which includes handling of human gametes outside body like in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), cryopreservation, donor gamete usage, assisted zona hatching (AZH), preimplantation genetic screening (PGS), and intrauterine insemination (IUI). Multiple pregnancy is most debatable issue associated with assisted reproductive technology. Multifetal gestations are considered as high-risk pregnancies with higher perinatal morbidity and mortality rate. Various meta-analysis in literature showed that singleton pregnancies born through assisted reproductive technologies after single embryo transfer or multiple embryo transfer are 1.8–2.1 times more prone to risk of preterm delivery when compared to pregnancies which are conceived spontaneously. Low birth weight, perinatal mortality, other obstetrical outcomes, congenital anomalies, chromosomal disorders, imprinting disorders, preimplantation genetic screening, blastocyst culture, assisted hatching, in vitro maturation, long-term consequelae in art born children, and other maternal factors which influence the outcome are discussed throughout this chapter.

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