This chapter covers a detailed discussion on patient safety. According to the Institute of Medicine (IOM), patient safety can be considered to be indistinguishable from the delivery of quality healthcare. Some practices which can be included in the category of patient safety practices include appropriate use of prophylaxis to prevent venous thromboembolism (VTE) in patients at risk, appropriate use of antibiotic prophylaxis in surgical patients to prevent post-operative infections, etc. One method of ensuring patient safety is the ability to correctly prioritise the patients depending on their level of urgency. OSCE (objective structured clinical examination) stations pertaining to prioritisation may check the doctor’s ability to set priorities in their clinical work. This chapter discusses 7 OSCE stations related to patent safety with different scenarios.