Pharmaceutical industry has multitrack approach for providing information to physicians. This is the commonest source of drug information for physicians and available through all channels of communication, i.e. verbal, written and computerized. These channels also include professional meeting, advertising in journals, direct mailing, medical representatives etc. Advertising is paid, one-way communication through a medium in which the sponsor is identified and the message is controlled. About 15–20% of budget of a pharmaceutical industry is for promotion of products. These advertisements highlight the advantages of the drug in question and the disadvantages or the limitations of the drug being suppressed. The general principles of advertising are also applied to drug advertising. Promotional activities of drugs by pharmaceutical companies are governed by Organization of Pharmaceutical Producers of India (OPPI) in India. OPPI is self-regulatory code of pharmaceutical marketing practices. Ethical criteria for drug promotion and source of drug information are also discussed in this chapter.