A prescription is a written order by a physician to a pharmacist to dispense a therapeutic agent to a patient. This therapeutic transaction is the sum of the physician’s evaluation of the problem. Prescriptions are typically handwritten on preprinted prescription forms that are assembled into pads, or alternatively printed onto similar forms using a computer printer. Preprinted on the form is text that identifies the document as a prescription, the name and address of the prescribing provider and any other legal requirement such as a registration number. The word “prescription” can be decomposed into “pre” and “script” and literally means, “to write before” a drug can be prepared. A prescription has various parts. Predating modern legal definitions of a prescription, a prescription traditionally is composed of four parts: a “superscription”, “inscription”, “subscription” and “signature”. Examples of prescriptions for common diseases: New format applicable from 2015 are also presented in this chapter, which are very helpful for the students.