Dental hypersensitivity is characterized by short, sharp pain arising from exposed dentin in response to stimuli such as thermal, evaporative, tactile, osmotic, or chemical and which cannot be ascribed to any other form of dental defect or pathology. Large number of population suffers from symptoms of dentin exposure at some time during their lifetime. Root sensitivity commonly occurs in the cervical area of the root, where cementum is extremely thin. The main symptoms of sensitivity of root include pain induced by cold or hot temperature, more frequently by cold, citrus fruits or sweet, or by contact with a toothbrush or dental instrument. Plaque control is primarily important for the reduction of hypersensitivity. The most frequently products used by the patients to relieve pain from hypersensitivity are desensitizing dentifrices, particularly toothpaste containing potassium salts like potassium nitrate, potassium citrate, and potassium chloride. Desensitizing agents used by dental professionals are cavity varnishes, anti-inflammatory agents, calcium compounds, fluoride compounds, iontophoresis, strontium chloride, restorative resins, and dentin bonding agents.