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Chapter-13 Multiple Sclerosis in India

BOOK TITLE: Practice Pearls in Neurology: Series 1

Author
1. Srinivasan AV
2. S Sujatha
3. M Kaushik Gowthaman
ISBN
9789352701988
DOI
10.5005/jp/books/14148_14
Edition
1/e
Publishing Year
2018
Pages
12
Author Affiliations
1. Institute of Neurology, Madras Medical College, Chennai, E-mail: avs19502000@yahoo.com, The Tamil Nadu Dr MGR Medical University; Institute of Neurology, Madras Medical College, Chennai, Tamil Nadu, India, Tamil Nadu Dr MGR Medical University, Chennai, Tamil Nadu, India, Institute of Neurology, Madras Medical College and Research Institute, Chennai, Tamil Nadu, India
2. Government Medical College, Thiruvananthapuram, Kerala, India, Vidya Sagar Special School, Koturrpuram Chennai, Tamil Nadu, India
3. Institute of Neurology, Madras Medical College, Chennai, Tamil Nadu, India
Chapter keywords
Multiple sclerosis, MS, central nervous system, CNS, relapsing remitting multiple sclerosis, RRMS, secondary progressive multiple sclerosis, SPMS, primary progressive multiple sclerosis, PPMS, progressive relapsing multiple sclerosis, PRMS

Abstract

Multiple sclerosis (MS) is an immune mediated disease mainly due to inflammation that results in disturbance and damage of myelinated axons in the brain (CNS). It is nothing but an ongoing disease with frequent episodes of neurologic deficits, which can be reversed. The clinical features vary because the location and extent of each attack varies. This chapter covers the incidence and prevalence of multiple sclerosis in India, phenotypic variability, environmental factors, genetic susceptibility, pathophysiology of multiple sclerosis, immune cells in multiple sclerosis, clinical features of multiple sclerosis, course of multiple sclerosis, and laboratory tests in multiple sclerosis.

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