Ventricular septal defects in certain anatomical locations are amenable for transcatheter closure. The most common variety of VSD is the perimembranous defects, which account for 75–80% of the defects. If the perimembranous VSD is anatomically restrictive, it may be amenable for transcatheter closure. Inlet defects need surgical closure and cannot be managed in catheterization lab. Defects in atrial septum are classified as secundum defects, when the defect is in the region of fossa ovalis, primum defects, when they are extension of partial atrioventricular canal defects, sinus venosus defects located in the region of drainage of superior or inferior vena cava into the right atrium, often associated with partial pulmonary venous drainage of right sided pulmonary veins, vestibular defects located in the region of triangle of Koch, and coronary sinus defects which represent unroofing of the coronary sinus.