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Chapter-28 Echocardiography in Dilated Cardiomyopathy

BOOK TITLE: Textbook of Echocardiography

Author
1. Ponde CK
2. Parekh Maulik
3. Ansari Mohsin
ISBN
9789352700929
DOI
10.5005/jp/books/14136_29
Edition
1/e
Publishing Year
2018
Pages
10
Author Affiliations
1. PD Hinduja National Hospital and MRC, Mumbai, Maharashtra, India, PD Hinduja National Hospital and MRC Hinduja Healthcare Surgical, Mumbai, Maharashtra, India, PD Hinduja National Hospital and Medical Research Centre, Mumbai, Maharashtra, India, PD Hinduja Hospital, Mumbai, Maharashtra, India, PD Hinduja National Hospital and MRC, Mahim Hinduja Healthcare Surgical Kar, Mumbai, Maharashtra, India, PD Hinduja National Hospital, Mumbai, Maharashtra, India, PD Hinduja Hospital, Mahim, Mumbai, Maharashtra, India
2. PD Hinduja National Hospital, Mumbai, Maharashtra, India, Parmanand Deepchand Hinduja National Hospital, Mumbai, Maharashtra, India, PD Hinduja Hospital, Mumbai, Maharashtra, India, Sir HN Reliance Foundation Hospital, Mumbai, Maharashtra, India
3. PD Hinduja Hospital, Mumbai, Maharashtra, India
Chapter keywords
Dilated cardiomyopathy, DCM, global longitudinal strain, GLS, ejection fraction, EF, LV systolic function, left ventricular, LV, myocardium

Abstract

Dilated cardiomyopathy (DCM) is defined as left ventricular (LV) cavity dilatation and systolic dysfunction of varying severity without significant atherosclerotic coronary artery disease or abnormal volume overload which can explain degree of LV impairment. It is the most frequent indication for cardiac transplantation in the western world. It is a final phenotype of a varied number of genetic and environmental insults to myocardium. This chapter covers the chamber dimensions, LV myocardial wall thickness, global LV and RV systolic function, Doppler echocardiography, and dyssynchrony. Global LV systolic function is invariably depressed and ejection fraction (EF) at the time of diagnosis is usually less the 35%. In the initial stages of disease, the EF can be borderline low (~ 50%) and in this group the impaired global longitudinal strain (GLS) is the earliest indicator of reduced LV systolic function. In this chapter, two cases are also described.

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