Chapter-06 Schizophrenia

BOOK TITLE: Textbook of Postgraduate Psychiatry (2 Volumes)

1. Shah Nilesh
2. Souza Avinash De
3. Shrivastava Shivanshu
4. Souza Allen De
Publishing Year
Author Affiliations
1. Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India
2. Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India
3. Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India
4. Desousa Foundation, Mumbai, Maharashtra, India
Chapter keywords
Schizophrenia, mood disorder, psychotic disorder, somatic treatment, epidemiology, neurobiology, genetic, psychotherapy, psychosocial rehabilitation


The aim of this chapter is to focus on the schizophrenia, other psychotic disorders and mood disorder. This chapter is divided into 12 parts following as introduction and overview, epidemiology of schizophrenia, neurobiology of schizophrenia, genetics of schizophrenia, clinical features of schizophrenia, somatic treatment of schizophrenia, psychosocial treatments of schizophrenia, role of psychotherapy, treatment resistant schizophrenia, psychosocial rehabilitation of schizophrenia, and the Indian scenario of schizophrenia. Schizophrenia is a chronic, severe, and disabling brain disease. Approximately 1% of the population develops schizophrenia during their lifetime. Although schizophrenia affects men and women with equal frequency, the disorder often appears earlier in men, usually in the late teens or early twenties, than in women, who are generally affected in the twenties to early thirties. The epidemiology of schizophrenia has progressed from descriptive accounts to a surge in analytic epidemiologic findings over the last two decades. This chapter reviews the epidemiology of schizophrenia, concentrating on results which are most credible methodologically and consistent across studies, focusing particularly on the most recent developments.

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