The third Indian Guidelines on Hypertension (IGH)-III were published in 2013 under the aegis of API. Epidemiology of hypertension is discussed. Hypertension in adults is defined as systolic blood pressure (SBP) of 140 mm Hg or above and/or diastolic blood pressure (DBP) of 90 mm Hg or above or any level of blood pressure in patients taking antihypertensive medication. Diagnosis of hypertension should be based on multiple blood pressure measurements taken on several separate occasions. Home blood pressure measurement (HBPM) that helps in initial evaluation of patients with hypertension and for monitoring the response to treatment should be used for follow-up of therapy. Ambulatory blood pressure measurement (ABPM) helps to identify nondippers and white-coat hypertension, evaluate drug-resistant hypertension, episodic hypertension, evaluate antihypertensive drugs and in individuals with hypotensive episodes while on antihypertensive medication. Goals of therapy, initiation, targets, nonpharmacologic therapy, pharmacologic therapy are the factors for management of hypertension. Antihypertensive drugs, combination therapy and newer modalities are discussed.