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Chapter-129 Management of Takayasu's Arteritis

BOOK TITLE: CSI: Cardiology Update 2014

Author
1. Tyagi Sanjay
2. Mittal Amit
ISBN
9789351526186
DOI
10.5005/jp/books/12415_130
Edition
1/e
Publishing Year
2015
Pages
9
Author Affiliations
1. GB Pant Hospital, Maulana Azad Medical College, New Delhi, India, G.B. Pant Hospital, Maulana Azad Medical College, New Delhi, India, GB Pant Institute of Postgraduate Medical Education & Research; GB Pant Institute & MAMC New Delhi, India, GB Pant Hospital, New Delhi, India, Maulana Azad Medical College; GB Pant Institute of Postgraduate Medical Education and Research, New Delhi, India, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, Maulana Azad Medical College, New Delhi, India, GB Pant Institute of, Postgraduate Medical Education and Research, GB Pant Institute of Postgraduate Medical Education and Research, Maulana Azad Medical College, New Delhi, India, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, Apollo Hospital Groups - North; GB Pant PGI and Dean MAMC, New Delhi, India
2. GB Pant Hospital, Maulana, Azad Medical College, New Delhi, India, Indraprastha Apollo Hospitals, New Delhi, India, Paras Hospital, Gurugram, Haryana, India, MM Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India
Chapter keywords
Takayasu’s arteritis, C-reactive protein, biomarkers, PTX3, endovascular intervention, Aortoplasty and Stenting, PTBA, aortoaortic bypass, antiproliferative agents

Abstract

Takayasu’s arteritis is a chronic granulomatous panarteritis involving aorta causes various types of aortoarterial stenosis or dilation. Diagnosis and assessment of disease activity includes the use of matrix metalloproteinase-9 and pentraxin and confirmed by periodic imaging with magnetic resonance angiography. Treatment strategy of Takayasu’s arteritis includes various pharmacologic therapy, treatment of hypertension and endovascular intervention. Endovascular intervention includes various methods for the treatment such as: subclavian angioplasty and stenting, aortoplasty and stenting, renal angioplasty and stenting, mesenteric angioplasty and stenting and pulmonary artery angioplasty. Various surgical procedures also used for the relief of ischemic symptoms in TA include aortocervical bypass, cervico-subclavian, aortocoronary bypass, aortoaortic bypass, aortic root replacement, renal artery bypass and nephrectomy. This chapter also discussed new perspectives and special considerations related to disease activity on treatment outcomes.

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