Ankylosed spine is susceptible to spinal injury following trivial trauma due to alteration in its biomechanics. The two most common types of ankylosing spinal disorders (ASD) are ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH). These are two completely different diseases that happen to share involvement of the axial skeleton and the peripheral entheses. Patients with ASD are prone to suffer from unstable three-column spinal trauma following trivial injury. Delayed diagnosis of the injury is common due to the patient- and surgeon-related factors. The presence of ankylosed spine in a trauma patient should alert the treating physician for an unstable spinal fracture. Computed tomography scan is superior to radiographs in diagnosing fractures in ASD. Fractures in ASD are associated with the higher incidences of spinal cord injuries than fractures in normal spines. Clinical and neurological outcome of patients with fractures secondary to ASD is worse compared to the general spinal trauma population. Surgical stabilization and decompression is the pre—ferred method of treating these fractures as it might be associated with lesser morbidity and better neurological outcomes than conservative care. Long-segment posterior fixation techniques are the mainstay of stabilization. The treatment of ankylosing spinal disorders is fraught with increased risks and complications. The surgical procedures are often technically demanding and require an experienced surgical team. In adept hands, the risk-benefit ratio of surgery is favorable making it a viable option when symptoms are severe.