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Chapter-59 Kyphoplasty of Symptomatic Vertebral Body Compression Fractures

BOOK TITLE: Spinal Infections and Trauma

Author
1. Agarwal Anand
2. Yeh John
3. Pflugmacher Robert
ISBN
9789350250754
DOI
10.5005/jp/books/11196_59
Edition
1/e
Publishing Year
2011
Pages
8
Author Affiliations
1. RP Centre for Ophthalmic Sciences, AIIMS, Ansari Nagar, New Delhi, India, University of Toledo, Ohio, USA, Director of Neuro Spine Research Queen Mary University of London UK, Consultant Orthopaedic and Spine Surgeon
2. St. Bartholomew’s and The Royal London Hospitals Queen Mary University of London, Department of Neurosurgery The Royal London Hospital Whitechapel London E1 1BB
3. University Medical School and Hospital of Bonn, Sigmund-Freud-Str. 25, Bonn Germany
Chapter keywords

Abstract

It is estimated that more than 100 million people worldwide are at risk for the development of fragility fractures secondary to osteoporosis according to the National Osteoporosis Foundation. Vertebral compression fracture occurs in 20% of people over the age of 70 years and in 16% of postmenopausal women. In the United States, VCFs account for more than $17 billion of annual direct cost. Osteoporotic VCFs can impair function, diminish physical and mental health and reduce quality of life to an extent underappreciated by many physicians and patients. Elderly patients with thoracic or lumbar fracture VCFs have a 4 to 5 years mortality rate that exceeds that of patients with hip fractures. The consequences of VCFs include pain with progressive vertebral body collapse resulting in spinal kyphosis. The pain associated with acute VCFs can be incapacitating and in certain number of cases become chronic. The chronic pain may be due to incomplete vertebral healing with progressive vertebral body collapse or the development of a pseudarthrosis at the involved vertebral body facture and/or altered spinal kinematics as a consequence of spinal deformity. This altered biomechanical environment due to the kyphotic deformity can lead to conditions accelerating additional vertebral body fractures. The kyphotic deformity shifts the patient’s center of gravity anteriorly, creating greater flexion bending moments, which increase the kyphotic angulations further and more loading to the anterior vertebral body leading ideal conditions for further additional fractures in the fragile vertebral body. The vertebral body adjacent to the previously fractured level is particularly at risk and the risk could be up to 25 times above baseline. Most untreated patients with VCFs fear falls. This is due to the kyphotic deformity leading to altered biomechanics where they hold their knee in flexion to balance themselves. This fear leads to prolonged inactivity leading to further bone loss and muscle deconditioning.7 Severe kyphosis can lead to the rib cage being positioned near or on the pelvic rim and can lead to severe pain and tenderness in the loin. The spinal deformity can also impair the pulmonary vital capacity and it has been reported that one thoracic VCF can result in 9% decrease in vital capacity. Kyphosis can also lead to pressure in the abdominal cavity resulting in poor appetite and nutritional deficiency.There is an increased mortality rate due to the above consequences of VCFs. To limit the consequences of spinal kyphotic deformity, it is prudent to take steps to prevent or correct the deformity.

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