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Chapter-120 Pathogenesis of Tumours of the Nervous System

BOOK TITLE: Ramamurthi and Tandon’s Textbook of Neurosurgery (3 Volumes)

Author
1. VV Radhakrishnan
ISBN
9789350250723
DOI
10.5005/jp/books/10307_120
Edition
3/e
Publishing Year
2012
Pages
11
Author Affiliations
1. Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India
Chapter keywords

Abstract

This chapter provides detail description of Pathogenesis of tumours of the nervous system. Pathogenesis of tumors of the nervous system, molecular pathogenesis of gliomas, tumor oncogenes, the 12q amplicon including CDK4 and MDM2, tumors suppressor genes (TSG), retinoblastoma gene, genetic instability, hereditary syndromes, oncogenic viruses, effect of radiation, radio frequency radiation, chemical carcinogens, immunodeficiency status, hormonal factors and trauma are described in detail. 94 references are included at the end of the chapter to facilitate further reading.

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