Skin and subcutaneous changes are an important component of facial aging. Facial aging was traditionally attributed to gravitational descent, but is now recognized as a result of loss of facial volume. Moreover, with aging and sun damage, the skin loses its elasticity and tone, allowing wrinkles to form easily in response to underlying facial muscles. Botulinum toxin and soft tissue fillers have revolutionized the rejuvenation of the aging face. Botulinum toxin has evolved greatly over the past 30 years since its introduction in the 1970s for the management of strabismus. Today, apart from its varied therapeutic indications in ophthalmic plastic surgery, it is widely used for erasing dynamic facial rhytids, such as lateral canthal wrinkles (crow’s feet), glabellar creases and horizontal forehead lines. Numerous soft tissue fillers ranging from bovine collagen to hyaluronic acid-derived products are currently available for static wrinkles and soft tissue augmentation. The two primary hallmarks of facial aging include wrinkles and loss of subcutaneous volume. An ophthalmologist can significantly contribute to the rejuvenation of the periorbital region and face. Lasers and injectables are the two main treatment modalities for the nonsurgical rejuvenation of the aging face.